Exposure to fine particulate matter associated with senile lentigo in Chinese women: a cross‐sectional study
Open accessAbstract
Background: Skin ageing especially senile lentigo directly affects self‐esteem. For decades, senile lentigo has been associated with chronic exposure to solar radiation. However, a study conducted recently in Caucasian subjects suggested that exposure to air pollution was significantly correlated with extrinsic skin ageing, in particular senile lentigines. Objective: To investigate the association between fine particulate matter ( PM 2.5 ) and skin ageing, particularly senile lentigo and seborrheic keratosis. Methods: The study enrolled 400 Chinese women aged 40–90 years including 210 from the Yanqing county in Beijing (low PM 2.5 exposure group) and 190 from the Xuanwumen in Beijing (high PM 2.5 exposure group). Skin ageing symptoms, particularly senile lentigines and seborrheic keratoses, were clinically assessed using scores of intrinsic and extrinsic skin ageing. An ordinal logistic regression model was used to analyse the effect of PM 2.5 on skin ageing adjusted for factors underlying skin ageing. Results: In the study population of Xuanwumen, we found that senile lentigo on cheeks and back of hands was 1.48 times and 2.8 times higher, respectively, compared with those from Yanqing county. However, no association was found between PM 2.5 and seborrheic keratosis. We found that other variables such as smoking, second‐hand smoking, contact with fossil fuels and skin types were significantly associated with skin ageing. Conclusion: These results indicate that PM 2.5 was another extrinsic factor promoting skin ageing.
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Women exposed to higher levels of PM2.5 showed more age-associated pigmentation, senile lentigines, on the face and hands.
“Similarly, a study from China found that women exposed to higher levels of PM2.5 showed more age-associated pigmentation (senile lentigines) on the face and hands85.”
From Air Pollution and Skin Diseases (2025) · cites this paper as [85]
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References 19 · Cited by 71
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- Authors
- Peng, F., Xue, C. ‐., Hwang, S. K., Li, W. ‐., Chen, Z., & Zhang, J. ‐.
- Affiliations
- Peking University People's Hospital (CN)
- Corresponding author
- Chen, Z.
- Venue
- Journal of the European Academy of Dermatology and Venereology
- Publisher
- Wiley
- Published
- 2016-09-05
- Volume
- 31
- Issue
- 2
- Pages
- 355-360
- ISSN
- 0926-9959 (ISSN-L)
- 1468-3083
- PMC
- PMC6084310
- OpenAlex
- W2515993405
- Cited by
- 71
- References
- 19
- Citations by year
- 2026: 2 · 2025: 12 · 2024: 4 · 2023: 6 · 2022: 10 · 2021: 12 · 2020: 5 · 2019: 13 · 2018: 4 · 2017: 3
- FWCI
- 8.01
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of the European Academy of Dermatology and Venereology (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- Chinese Medical Association (2119000206)
- National Natural Science Foundation of China (81472902)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Keywords
- PM2.5, air pollution, senile lentigo, seborrheic keratosis, skin aging, Chinese women, smoking, passive smoking, skin type
- MeSH terms
- Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Humans, Lentigo, Middle Aged, Skin Aging, Particulate Matter
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