Alpha‐ketoglutarate dehydrogenase complex‐dependent succinylation of proteins in neurons and neuronal cell lines

Gibson, Gary E., Xu, Hui, Chen, Huan‐Lian, Chen, Wei, Denton, Travis T., Zhang, Sheng·2015·Journal of Neurochemistry

Cited by (136)

Items 101–136 of 136

  1. Lysine succinylation as a metabolic switch in cardiovascular diseases: Mechanistic insights and therapeutic perspectives
    Fei Mu, Haiyue Zhang, Rui Gong, Rui Jun Lin, Meina Zhao, Xingru Tao, Lei Shang, Miaomiao Xi, Jinyi Zhao, Jingwen Wang · 2025 · Redox Biology
  2. Protocol for a seamless phase 2A-phase 2B randomized double-blind placebo-controlled trial to evaluate the safety and efficacy of benfotiamine in patients with early Alzheimer’s disease (BenfoTeam)
    Howard Feldman, Jose Alejandro Luchsinger, Gabriel C. Léger, Curtis S. Taylor, Diane M. Jacobs, David P. Salmon, Steven D. Edland, Karen S. Messer, Carolyn Revta, Sarah A. Flowers et al. · 2024 · PLoS ONE
  3. The delayed effect of rotenone on the relative content of brain isatin-binding proteins of rats with experimental parkinsonism
    О.А. Бунеева, Инга Геннадиевна Капица, L.Sh. Kazieva, Nikita E. Vavilov, Victor Gavrilovich Zgoda, A. E. Medvedev · 2024 · Biomeditsinskaya Khimiya
  4. Unveiling the importance of SIRT5 for cardiac health and disease in an era of increasing longevity
    Arkadiusz Grzeczka, Szymon Graczyk, Paweł Kordowitzki · 2025 · GeroScience
  5. Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML
    Ang Jia, Xiaowen Zhang, Jihao Zhou, Yongcan Ma, Jing Wang, Yongbo Gong, Wenjie Song, Hangcheng Hu, Yufei Yu, Haixia Yang et al. · 2026 · Cell Metabolism
  6. Acylation of the Rat Brain Proteins is Affected by the Inhibition of Pyruvate Dehydrogenase in vivo
    Vasily A. Aleshin, Daria A. Sibiryakina, Alexey V. Kazantsev, Anastasia V. Graf, Victoria I. Bunik · 2023 · Biochemistry (Moscow)
  7. NMR Metabolomic Profiling of Differentiated SH-SY5Y Neuronal Cells: Amyloid-β Toxicity and Protective Effects of Galantamine and Lycorine
    Arian Kola, Filippo Costanti, Jordan Kahfi, Abdul-Hamid M. Emwas, Mariusz Jaremko, Daniela Valensin · 2025 · Cells
  8. An Update on Developments in the Field of Thiamin Diphosphate-Dependent Enzymes
    Frank Jordan, Natalia S. Nemeria, Anand Balakrishnan, Joydeep Chakraborty, Elena L. Guevara, Pradeep Reddy Nareddy, Hetal D. Patel, Da Jeong Shim, Junjie Wang, Luying Yang et al. · 2020 · Elsevier eBooks
  9. Quantitative proteome and lysine succinylome characterization of zinc chloride smoke-induced lung injury in mice
    Rui Zhou, Zhiwei Tu, Daishi Chen, Wanmei Wang, Shuzi Liu, Linjun She, Zhan Li, Jihong Liu, Yabin Li, Yu Cui et al. · 2024 · Heliyon
  10. Identification of Mitochondrial and Succinylation Modification-Related Gene Signature in Ischemic Stroke
    Lixia Wang, Jishuai Zhao, Hui Cai, Xiaoling Ying, Yonglei Liu, Zeming Luo, Heyan Chen, Lin Yang · 2025 · Molecular Neurobiology
  11. y-mtPTM: Yeast mitochondrial posttranslational modification database
    Broňa Brejová, Veronika Vozáriková, Ivan Agarský, Hana Derková, Matej Fedor, Dominika Harmanová, Lukáš Kiss, Andrej Korman, Martin Pašen, Filip Brázdovič et al. · 2023 · Genetics
  12. The role of succinylation-mediated metabolic reprogramming in tumor progression
    Siyi He, Chunduo Wang, Ranran Li, Kexin Xu, Wenjia Zhang, Binbin Feng, Sheng‐Tao Cheng, Ji‐Hua Ren, Juan Chen · 2025 · Molecular Biology Reports
  13. EXPANDING THE FRONTIERS OF SUCCINATE-CONTAINING DIALYSATE’S EFFECTS
    Р В Голубев, Alexey V. Smirnov · 2017 · Nephrology (Saint-Petersburg)
  14. Energy Metabolism | 2-Oxoglutarate Dehydrogenase Complex
    Victoria I. Bunik, Tristan Wagner, Marco Bellinzoni · 2021 · Elsevier eBooks
  15. STA regulates succinylated AflM triggered by SCS to contribute to aflatoxin biosynthesis through the Ach1
    Rui Xie, Zhenhong Zhuang, Qionghui Chen, Chunlan Xie, John Adejor, Xinyi Nie, Shihua Wang · 2025 · Virulence
  16. ATP5A1 succinylation as a key driver for the transition of myocardial ischemia to development of heart failure
    Lujing Jiang, Shanshan Chen, Senlin Li, Cui Liu, Changmin Xie, Yu He, Yani Shi, Fang Liu, Chengyang Lai, Qingfeng Xie et al. · 2026 · Basic Research in Cardiology
  17. The neuroprotective effect of isatin in the rotenone-induced model of parkinonism in rats: the study of delayed effects
    О.А. Бунеева, Инга Геннадиевна Капица, L.Sh. Kazieva, Nikita E. Vavilov, Victor Gavrilovich Zgoda, Alexey E. Medvedev · 2024 · Biomeditsinskaya Khimiya
  18. α-Ketoglutarate Is a Circulatory Exercise Factor That Promotes Learning and Memory Recall and Has Antidepressant Properties
    Fady Eid, Perla El Ahmad, Reine El Khoury, Diala El Masri, Yara El Zoghby, Yasmin Sahlloul, Joanna Fadel, Zena L. Haddad, Amar Mezher, Litsa Maria Ghayad et al. · 2025 · Biological Psychiatry Global Open Science
  19. Protein succinylation in tumors-from biology to clinical therapy
    Huiling Li, Huijuan Zhang, Jing Zhu, Yu Tang, Jing An · 2025 · International Journal of Biological Macromolecules
  20. Protein succinylation in disease: Mechanistic insights and therapeutic targeting
    Wenbo Li, Junying Li · 2026 · Genes & Diseases
  21. Effect of low doses of bezafibrate and fenofibrate on liver 2-oxo-glutarate dehydrogenase complex in low-protein diet fed rats
    Malgorzata Elzbieta Knapik-Czajka · 2015 · Bangladesh Journal of Pharmacology
  22. Understanding of the 2-oxoglutarate dehydrogenase and 2-oxoadipate dehydrogenase assembly with the E2o core relevant to a hybrid complex formation
    Xu Zhang, Natalia S. Nemeria, Frank Jordan · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  23. Regulation | Post Translational Modifications by Succinylation and Acetylation
    Diana M. Acosta, David Eliezer, Gary E. Gibson · 2021 · Elsevier eBooks
  24. Elucidating Syntrophic Metabolism through Noncanonical Protein Modifications and Protein Sequences
    Hanh T.H. Nguyen · 2015 · eScholarship (California Digital Library)
  25. Small change, big impact: functional characterization of human SIRT5 variants
    Taolin Yuan · 2021
  26. Ischemic Succinate Accumulation Inhibits Neural Stem Cell Proliferation after Cerebral Ischemia/Reperfusion via Inducing Cdc42 Succinylation
    Linyan Huang, Juyun Ma, Jinxiu Song, Jingjing Xu, Haidi Fan, Heng Cai, Wan Wang, Yanling Wang, Zhaoli Hu, Jiangang Shen et al. · 2021 · Research Square
  27. Acylation of the rat brain proteins is affected by the inhibition of pyruvate dehydrogenase in vivo
    Vasily A. Aleshin, Daria A. Sibiryakina, A. V Kazantsev, Anastasia V. Graf, Victoria I. Bunik · 2023 · Biochemistry (Moscow)
  28. Novel protein acylations in Alzheimer’s disease: Molecular, mechanisms, biological significance, and diagnostic and therapeutic potentials
    Yue Yang, Zhihua Yu, Rui Gao, Yuehua Zhang, Ziyi Zhang, Xin Zhong, Linchi Jiao, Ke Du, Yuqiang Wu, Minjie Wei et al. · 2025 · Journal of Advanced Research
  29. Additional file 1 of Unstructured regions of large enzymatic complexes control the availability of metabolites with signaling functions
    Ioannis Skalidis, Christian Tüting, Panagiotis L. Kastritis · 2020 · Figshare
  30. Alpha-2-Macroglobulin Mitigates Mitochondrial Dysfunction and Neuronal Apoptotic Responses in Pesticide-induced Neurotoxicity
    Swati Dixit · 2025 · American Journal of Biomedical and Life Sciences
  31. Processes and therapeutic perspectives of acylation modifications of lysine and cysteine in tumors
    Jialin Jiang, Jiabin Chen, Shuhang Huang, Yue Tian, Lanyu Liu, Jiahui Yao, Yuzhu Zhang, Can Jiang, Xingting Zhang, Na Han et al. · 2026 · Cell Communication and Signaling
  32. The role and therapeutic potential of succinate and succinylation in cardiovascular diseases
    Wenyan Liu, Yu Han, Fengquan Zhang, Shuai Leng, Wenqian Yu · 2026 · Clinical Epigenetics
  33. Caractérisation de cibles thérapeutiques innovantes pour lutter contre la bactérie Acinetobacter baumannii
    Brandon Robin · 2021
  34. Interplay between Neuronal Metabolism and Signaling in Model Systems with Impaired α-Ketoglutarate Dehydrogenase Complex Activity
    Márton Kokas, Attila Ambrus, László Tretter, Tímea Komlódi · 2026 · Biochemistry (Moscow)
  35. Alpha-ketoglutarate dehydrogenase and citric acid cycle flexibility in heart disease and failure
    Nadia Martínez Naya, Abigail R. Heath, Gustavo Adolfo Gámez de Armas, Keith A. Webster, Lina A. Shehadeh · 2026 · American Journal of Physiology-Heart and Circulatory Physiology
  36. Post-Translational Protein Acylation in Atrial Fibrillation
    Yi Zhang, Guo‐Wei He · 2026 · Journal of Cardiovascular Translational Research