Endo‐lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?

Cited by (150)

Items 101–150 of 150

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5. Transcriptional targets of senataxin and E2 promoter binding factors are associated with neuro-degenerative pathways during increased autophagic flux
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6. Herpes Simplex Virus Type 1 Induces AD-like Neurodegeneration Markers in Human Progenitor and Differentiated ReNcell VM Cells
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7. Decoding senescent drivers in Alzheimer's disease: From bench to bedside
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9. Linking endo-lysosomal pH, sterol, and trafficking to neurodegenerative disease
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10. Drosophila melanogaster models of MPS IIIC ( Hgsnat ‐deficiency) highlight the role of glia in disease presentation
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11. Bromelain prevents Alzheimer's disease progression by suppressing oxidative stress and upregulating apolipoprotein A1 in 5x familial Alzheimer's disease transgenic mice
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12. Recent Treatment Strategies in Alzheimer's Disease and Chronic Traumatic Encephalopathy
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13. A systems biology-based identification and in vivo functional screening of Alzheimer’s disease risk genes reveal modulators of memory function
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14. Structure-performance relationships of four lysosomal markers used for the imaging of HT-29 cancer cells and a cellular model of lysosomal storage disease (Niemann-Pick C)
    Diego Navarro‐Barreda, Begoña Bedrina, César A. Angulo‐Pachón, Juan F. Miravet, Dolores Pérez‐Sala, Francisco Galindo · 2022 · Dyes and Pigments
15. Multimodal Blood-Based Biomarker Panel Reveals Altered Lysosomal Ionic Content in Alzheimer’s Disease
    Senthilkumar Deivasigamani, Shareefa Thekkan, Hernando Martínez Vergara, Owen M. Connolly, Mali L. Cosden, Thienlong Phan, Sean Smith, Jacob Marcus, Jason M. Uslaner, Dhivya Venkat et al. · 2024 · ACS Chemical Biology
16. Down syndrome fibroblasts exhibit diminished autophagic clearance and endosomal dysfunction after serum starvation
    Stefanos Aivazidis, Abhilasha Jain, Colin C. Anderson, David J. Orlicky, Abhishek K. Rauniyar, Kristofer S. Fritz, Peter S. Harris, David M. Siegel, Kenneth N. Maclean, James R. Roede · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
17. Pharmacological mechanisms and therapeutic prospects of plant metabolites from traditional Chinese medicine in regulating programmed cell death in Alzheimer’s disease
    Pengyu Pan, Tengyu Zhao, Jian Zhang, Yuhan Zhou, Xinyue Zhang, Quan Li, Yanyan Zhou · 2025 · Frontiers in Pharmacology
18. Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse
    Seungmin Lee, In Gyoung Ju, Hyeyoon Eo, Jin Hee Kim, Yujin Choi, Myung Sook Oh · 2024 · Chinese Medicine
19. Analysis of the causal relationship between five chosen factors and early-onset Alzheimer's disease: A Mendelian randomization study
    Chunxin Lu, Jiechao Zhou · 2025 · Journal of Alzheimer s Disease
20. Heat Shock Protein70 in Neurological Disease
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21. Therapeutic approaches in proteinopathies
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22. Toxic effects of endoplasmic reticulum stress transducer BBF2H7-derived small peptide fragments on neuronal cells
    Koji Matsuhisa, Longjie Cai, Atsushi Saito, Fumika Sakaue, Yasunao F. Kamikawa, Sachiko Fujiwara, Rie Asada, Yukitsuka Kudo, Kazunori Imaizumi · 2020 · Brain Research
23. Autophagy Monitoring in Cerebral Pericytes from Alzheimer’s disease Mouse Model in an Inflammatory Environment
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24. Soluble 4R0N Tau Abrogates Endocytic Vesicular Dynamics
    Tharun Selvam Mahendran, Shwetha Suresh, Lakshmi Garimella, Ravi R. Manjithaya · 2020 · Frontiers in Aging Neuroscience
25. Evaluation of the Endo-Lysosomal System and the Ubiquitin-Proteasome System in Neurodegenerative Diseases
    Simon Sjödin · 2018 · Gothenburg University Publications Electronic Archive (Gothenburg University)
26. Commentary on interactions between neurotropic pathogens, neuroinflammatory pathways, and autophagic neural cell death
    Michaela Iva Cellina, Marcello Orsi · 2018 · Neuroimmunology and Neuroinflammation
27. Ανάλυση γενετικών και βιολογικών δεικτών σε ασθενείς με νόσο Alzheimer
    Πολυξένη Σταμάτη · 2020
28. Human brain mitochondrial-nuclear cross-talk is cell-type specific and is perturbed by neurodegeneration
    Aine Fairbrother-Browne, Aminah Tasnim Ali, Regina Hertfelder Reynolds, Sonia García-Ruiz, David Zhang, Zhongbo Chen, Mina Ryten, Alan Hodgkinson · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
29. Perspective Chapter: Alzheimer - A Complex Genetic Background
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30. Macro- and nanoscale self-assembled amino acid derivatives as reduction-sensitive and photoactive materials
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31. Sex differences in response to obesity and caloric restriction on cognition and hippocampal markers of autophagic-lysosomal pathway function
    Sadie B. Baer, Adrianah D. Dorn, Danielle Maria Osborne · 2023 · Research Square
32. Cross Talk Between Al and Genetic Susceptibility in AD
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33. Identification of lysosome-related genes in gastric cancer and development of a prognostic model
    Zihao Wei, Zhengrui Wang, Zi Chen, Dongmei Luo · 2024 · Research Square
34. Targeting lysosomal damage is a new therapeutic perspective for Duchenne Muscular Dystrophy
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35. APP ubiquitination by VHL protein is essential for MVB sorting and lysosomal degradation
    Chunyan Shan, Rixu Cong, Xiangyu Xu, Yuanjun Li, Yonglu Tian, Wenyuan Cao, Wei Zhao, Linqing Miao, Junlin Teng, Ning Huang et al. · 2025 · Journal of Molecular Cell Biology
36. Additional file 1 of Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse
    Seungmin Lee, Ju, In Gyoung, Hyeyoon Eo, Kim, Jin Hee, Yujin Choi, Myung Sook Oh · 2024 · Figshare
37. Additional file 1 of Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer’s disease brains
    Sharoar, Md Golam, Sarah Ilona Palko, Ge, Yingying, Saido, Takaomi C., Yan, Riqiang · 2021 · Figshare
38. Additional file 2 of Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer’s disease brains
    Sharoar, Md Golam, Sarah Ilona Palko, Ge, Yingying, Saido, Takaomi C., Yan, Riqiang · 2021 · Figshare
39. Alzheimer’s disease PSEN-2 N141I variant alters trafficking of amyloid beta oligomers in iPSC-derived brain endothelial-like cells
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40. Introduction of neurobiology and type 2 diabetes
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41. Aerobic exercise intervention in Alzheimer's disease: Proteomic insights into peripheral T cell–mediated immune pathways
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42. Altérations des synapses et des corps cellulaires neuronaux chez les souris APPxPS1-KI et dans la Maladie d'Alzheimer
    Alexandre Androuin · 2018 · theses.fr (ABES)
43. Implication de nouvelles cibles microgliales, Cst7 et Clec7a/Dectin-1, dans le développement et la progression de la maladie d'Alzheimer
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44. Studying the role of human Amyloid Precursor Protein (APP) during human cortical neurogenesis
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45. Lysosomal defects in Duchenne muscular dystrophy : advancing combined therapeutic approaches
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46. An Engineered Multifunctional Fusion Protein Targeting Aβ Oligomers, Microglia and Autophagy Ameliorates Cognitive Deficits and Amyloid Pathology in Alzheimer’s Disease Mice
    J ZHU, Yaru Huang, Fengqian Chen, Meiqi Wang, Xiao-lin Yu, Guifeng Zhang, Rui‐tian Liu · 2026 · Cellular and Molecular Neurobiology
47. Endolysosomal pathway and autophagy dysregulation in Alzheimer’s disease
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48. Estrogen deprivation exacerbates Alzheimer’s disease pathology through neuronal CTSS signaling
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49. Genetic and molecular evidence linking CTSH to Alzheimer's disease pathophysiology
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50. BindingDB Entry 50021669: Small molecules targeting molecular chaperones for tau regulation: Achievements and challenges.
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