Impact of chronic variable stress on neuroendocrine hypothalamus and pituitary in male and female C57BL/6J mice

Nair, Betina B.; Khant Aung, Zin; Porteous, Robert; Prescott, Melanie; Glendining, Kelly A.; Jenkins, Danielle E.; Augustine, Rachael A.; Silva, Mauro S.B.; Yip, Siew H.; Bouwer, Gregory T.; Brown, Colin H.; Jasoni, Christine L.; Campbell, Rebecca E.; Bunn, Stephen J.; Anderson, Greg M.; Grattan, David R.; Herbison, Allan E.; Iremonger, Karl J.

doi:10.1111/jne.12972

Impact of chronic variable stress on neuroendocrine hypothalamus and pituitary in male and female C57BL/6J mice

Chronic stress exerts multiple negative effects on the physiology and health of an individual. In the present study, we examined hypothalamic, pituitary and endocrine responses to 14 days of chronic variable stress (CVS) in male and female C57BL/6J mice. In both sexes, CVS induced a significant d…