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Methods and theory in bone modeling drift: comparing spatial analyses of primary bone distributions in the human humerus
Open accessAbstract
This study compares two novel methods quantifying bone shaft tissue distributions, and relates observations on human humeral growth patterns for applications in anthropological and anatomical research. Microstructural variation in compact bone occurs due to developmental and mechanically adaptive circumstances that are ‘recorded’ by forming bone and are important for interpretations of growth, health, physical activity, adaptation, and identity in the past and present. Those interpretations hinge on a detailed understanding of the modeling process by which bones achieve their diametric shape, diaphyseal curvature, and general position relative to other elements. Bone modeling is a complex aspect of growth, potentially causing the shaft to drift transversely through formation and resorption on opposing cortices. Unfortunately, the specifics of modeling drift are largely unknown for most skeletal elements. Moreover, bone modeling has seen little quantitative methodological development compared with secondary bone processes, such as intracortical remodeling. The techniques proposed here, starburst point‐count and 45° cross‐polarization hand‐drawn histomorphometry, permit the statistical and populational analysis of human primary tissue distributions and provide similar results despite being suitable for different applications. This analysis of a pooled archaeological and modern skeletal sample confirms the importance of extreme asymmetry in bone modeling as a major determinant of microstructural variation in diaphyses. Specifically, humeral drift is posteromedial in the human humerus, accompanied by a significant rotational trend. In general, results encourage the usage of endocortical primary bone distributions as an indicator and summary of bone modeling drift, enabling quantitative analysis by direction and proportion in other elements and populations.
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“This implies the existence of a modeling drift, which moves a bone structural unit over time in the direction defined by growth patterns, and adjusts the bone mass distribution to the stresses and strains induced by locomotion and physical activity.3”
From Bone remodeling: an operational process ensuring survival and bone mechanical competence (2022) · cites this paper as [3]
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Cited by
Sorted by citations
Bone remodeling: an operational process ensuring survival and bone mechanical competence
Bolamperti, S., Villa, I., & Rubinacci, A. (2022) · Bone Research · doi:10.1038/s41413-022-00219-8 · Cited by 482
Metadata
- Authors
- Maggiano, C. M., Maggiano, I. S., Tiesler, V. G., Chi‐Keb, J. R., & Stout, S. D.
- Affiliations
- Western University (CA)
- University of Saskatchewan (CA)
- Autonomous University of Yucatán (MX)
- Department for Anthropological Sciences Universidad Autónoma de Yucatán Mérida Yucatán Mexico
- The Ohio State University (US)
- Corresponding author
- Maggiano, Corey M.
- Venue
- Journal of Anatomy
- Publisher
- Wiley
- Published
- 2015-10-15
- Volume
- 228
- Issue
- 1
- Pages
- 190-202
- ISSN
- 0021-8782 (ISSN-L)
- 1469-7580
- PMC
- PMC4694161
- OpenAlex
- W2177331110
- Cited by
- 28
- References
- 51
- Citations by year
- 2025: 5 · 2024: 3 · 2022: 4 · 2021: 4 · 2020: 1 · 2019: 3 · 2018: 1 · 2017: 2 · 2016: 4 · 2015: 1
- FWCI
- 17.24
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Anatomy (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation (DDIG #1061169)
- Deutsche Forschungsgemeinschaft (MA 4702/1‐1)
- Topics
- Social Sciences › Arts and Humanities › Archeology (arts and humanities) › Forensic Anthropology and Bioarchaeology Studies
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bone Metabolism and Diseases
- Keywords
- humerus, bone microarchitecture, bone growth, bone resorption, skeletal asymmetry, archaeological skeletal remains
- MeSH terms
- Adaptation, Physiological, Adolescent, Adult, Aged, Biomechanical Phenomena, Bone Development, Cadaver, Child, Child, Preschool, Female, Humans, Humerus, Male, Middle Aged, Bone Remodeling, Diaphyses, Young Adult
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