Cited by 28Veterinary Medicine and SurgeryAnimal Nutrition and PhysiologyFood and Agricultural Sciences

Evaluation of phosphorus, calcium, and magnesium content in commercially available foods formulated for healthy cats

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Summers, Stacie C., Stockman, Jonathan, Larsen, Jennifer A., Zhang, Lei, Rodriguez, Anais Sanchez·2020·Journal of Veterinary Internal Medicine

Abstract

Background: High dietary phosphorus (P) and low calcium-to-phosphorus ratio (Ca:P) are associated with kidney damage in cats. There are no established guidelines for dietary P maximum for cats. Objectives: To quantify crude protein, P, Ca, and magnesium (Mg) concentrations in cat foods and compare among food formats (dry, canned, raw), primary protein ingredients, protein concentrations (low, moderate, high), grain-free versus grain-containing foods, foods intended for adult maintenance versus all life stages, and cost. Samples: Eighty-two commercial nonprescription cat foods. Methods: Descriptive study. Mineral concentrations were measured using inductively coupled argon plasma-optical emission spectroscopy. Crude protein was measured using the Dumas nitrogen combustion method. Mineral and crude protein concentrations were compared among food categories. Results: Twenty-seven foods contained ≥3.6 g P/1000 kcal metabolizable energy (ME), of which 7 exceeded 4.8 g/1000 kcal ME. Thirteen foods had low Ca:P ratio (≤1.0). The low-protein diet group had no products ≥3.6 g P/1000 kcal ME, which was significantly different compared to the high-protein diet group (52% of products had ≥3.6 g P/1000 kcal ME; P = .01). No significant differences in P content and Ca:P ratio were found among other diet categories. Canned foods had significantly lower Mg compared to dry (P < .001) and raw (P = .007) foods. Declared minimum P and Ca were significantly lower than analyzed concentrations (P = .0005 and P = .003, respectively). Conclusions and Clinical Importance: The high number of foods with high P and low Ca suggest that pet food regulatory reform should be considered.

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  • Significant variability has been documented among pet foods marketed for senior dogs.

    “Significant variability has been documented among pet foods marketed for senior dogs.103,106”

    From 2021 AAHA Nutrition and Weight Management Guidelines for Dogs and Cats (2021) · cites this paper as [103]

    The Discussion reports highly variable phosphorus and calcium concentrations among commercial cat foods. The Materials and Methods specify foods labeled for adult maintenance or all life stages; the paper does not document variability among foods marketed for senior dogs. No page numbers are available in our copy. (LLM, conf=0.87)

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  • There is no consensus among different pet food manufacturers about what should constitute a "senior" pet food.

    “there is no consensus among different pet food manufacturers about what should constitute a “senior” pet food.”

    From 2021 AAHA Nutrition and Weight Management Guidelines for Dogs and Cats (2021) · cites this paper as [103]

    The Materials and Methods section describes foods labeled for adult maintenance or all life stages, and the Results describe their nutritional adequacy statements. Neither section addresses how manufacturers define “senior” pet food or whether they agree on a definition (searched: senior pet food, manufacturer consensus, older-cat life stages). (LLM, conf=0.76)

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  • Dogs and cats can shed Salmonella without exhibiting any clinical signs of disease.

    “dogs and cats can shed Salmonella without exhibiting any clinical signs of disease.97,102,103”

    From 2021 AAHA Nutrition and Weight Management Guidelines for Dogs and Cats (2021) · cites this paper as [103]

    The Introduction and Discussion address dietary phosphorus and kidney disease in cats, not Salmonella shedding. Searches of our copy for asymptomatic Salmonella shedding and for shedding without clinical signs found no passage addressing the claim. (LLM, conf=0.76)

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Research works printed but not linked: 35

  1. [1]Marino CL, Lascelles BDX, Vaden SL, Gruen ME, Marks SL. Prevalence and classification of chronic kidney disease in cats randomly selected from four age groups and in cats recruited for degenerative joint disease studies. J Feline Med Surg. 2014; 16(6): 465‐ 472. 24217707 PMC4414065
  2. [2]Elliott J, Barber PJ. Feline chronic renal failure: clinical findings in 80 cases diagnosed between 1992 and 1995. J Small Anim Pract. 1998; 39(2): 78‐ 85. 9513888
  3. [3]Markovich JE, Freeman LM, Labato MA, Heinze CR. Survey of dietary and medication practices of owners of cats with chronic kidney disease. J Feline Med Surg. 2015; 17(12): 979‐ 983. 25535212 PMC10816345
  4. [4]Dobenecker B, Webel A, Reese S, Kienzle E. Effect of a high phosphorus diet on indicators of renal health in cats. J Feline Med Surg. 2018; 20(4): 339‐ 343. 28569079 PMC11129231
  5. [5]Alexander J, Stockman J, Atwal J, et al. Effects of the long‐term feeding of diets enriched with inorganic phosphorus on the adult feline kidney and phosphorus metabolism. Br J Nutr. 2018; 121: 1‐ 21. 10.1017/S0007114518002751. 30572965 PMC6390406 · DOI
  6. [6]Paunier L. Effect of magnesium on phosphorus and calcium metabolism. Monatsschr Kinderheilkd. 1992; 140(9 Suppl 1): S17‐ S20. 1331782
  7. [7]Pastoor FJ, Van 't Klooster AT, Mathot JN, et al. Increasing calcium intakes lower urinary concentrations of phosphorus and magnesium in adult ovariectomized cats. J Nutr. 1994; 124(2): 299‐ 304. 8308580
  8. [8]National Research Council. Nutrient Requirements of Dogs and Cats. Washington, DC: The National Academy Press; 2006.
  9. [9]Association of American Feed Control Officials. Model Regulations for Pet Food and Specialty Pet Food under the Model Bill: 2019 Official Publication. Oxford, IN: Association of American Feed Control Officials; 2019: 139‐ 204.
  10. [11]Gagne JW, Wakshlag JJ, Center SA, et al. Evaluation of calcium, phosphorus, and selected trace mineral status in commercially available dry foods formulated for dogs. J Am Vet Med Assoc. 2013; 243(5): 658‐ 666. 23971845
  11. [13]Case LPLD, Hayek MG, et al. Canine and Feline Nutrition: a Resource for Companion Animal Professionals. 3rd ed. Maryland Heights, MO: Elsevier Inc; 2011.
  12. [14]Loganathan A, Tan K‐S, Moore J, et al. A case of acute phosphate nephropathy. Med J Aust. 2016; 204(5): 183e1. 26985842
  13. [15]Pálmadóttir VK, Gudmundsson H, Hardarson S, Árnadóttir M, Magnússon T, Andrésdóttir MB. Incidence and outcome of acute phosphate nephropathy in Iceland. PLoS One. 2010; 5(10): e13484. 20976065 PMC2957439
  14. [16]Mackay EM, Oliver J. Renal damage following the ingestion of a diet containing an excess of inorganic phosphate. J Exp Med. 1935; 61(3): 319‐ 334. 19870361 PMC2133223
  15. [17]Schneider P, Muller‐Peddinghaus R, Pappritz G, et al. Potassium hydrogen phosphate induced nephropathy in the dog: glomerular alterations. Vet Pathol. 1980; 17(6): 720‐ 737. 7423831
  16. [18]Pastoor FJ, Van 't Klooster AT, Mathot JN, et al. Increasing phosphorus intake reduces urinary concentrations of magnesium and calcium in adult ovariectomized cats fed purified diets. J Nutr. 1995; 125(5): 1334‐ 1341. 7738692
  17. [19]Markowitz GS. Acute phosphate nephropathy following oral sodium phosphate bowel purgative: an underrecognized cause of chronic renal failure. J Am Soc Nephrol. 2005; 16(11): 3389‐ 3396. 16192415
  18. [20]Fernández‐Juárez G, Parejo L, Villacorta J, et al. Kidney injury after sodium phosphate solution beyond the acute renal failure. Nefrologia. 2016; 36(3): 243‐ 248. 27087365
  19. [21]Fogo AB, Lusco MA, Najafian B, Alpers CE. AJKD atlas of renal pathology: nephrocalcinosis and acute phosphate nephropathy. Am J Kidney Dis. 2017; 69(3): e17‐ e18. 28236887
  20. [22]Brown CA, Elliott J, Schmiedt CW, Brown SA. Chronic kidney disease in aged cats: clinical features, morphology, and proposed pathogeneses. Vet Pathol. 2016; 53(2): 309‐ 326. 26869151
  21. [23]Böswald LF, Kienzle E, Dobenecker B. Observation about phosphorus and protein supply in cats and dogs prior to the diagnosis of chronic kidney disease. J Anim Physiol Anim Nutr. 2018; 102(Suppl 1): 31‐ 36. 29623690
  22. [24]Masuyama R, Nakaya Y, Katsumata S, et al. Dietary calcium and phosphorus ratio regulates bone mineralization and turnover in vitamin D receptor knockout mice by affecting intestinal calcium and phosphorus absorption. J Bone Miner Res. 2003; 18(7): 1217‐ 1226. 12854831
  23. [25]Calvo MS. Dietary phosphorus, calcium metabolism and bone. J Nutr. 1993; 123(9): 1627‐ 1633. 8360792
  24. [26]Kemi VE, Karkkainen MU, Rita HJ, et al. Low calcium:phosphorus ratio in habitual diets affects serum parathyroid hormone concentration and calcium metabolism in healthy women with adequate calcium intake. Br J Nutr. 2010; 103(4): 561‐ 568. 19781123
  25. [27]Finch NC, Geddes RF, Syme HM, Elliott J. Fibroblast growth factor 23 (FGF‐23) concentrations in cats with early nonazotemic chronic kidney disease (CKD) and in healthy geriatric cats. J Vet Intern Med. 2013; 27(2): 227‐ 233. 23363336
  26. [28]Howard KA, Rogers QR, Morris JG. Magnesium requirement of kittens is increased by high dietary calcium. J Nutr. 1998; 128(12 Suppl): 2601s‐ 2602s. 9868215
  27. [29]Pastoor FJ, Opitz R, Van 't Klooster AT, et al. Dietary calcium chloride vs. calcium carbonate reduces urinary pH and phosphorus concentration, improves bone mineralization and depresses kidney calcium level in cats. J Nutr. 1994; 124(11): 2212‐ 2222. 7965206
  28. [30]Gutierrez OM. Sodium‐ and phosphorus‐based food additives: persistent but surmountable hurdles in the management of nutrition in chronic kidney disease. Adv Chronic Kidney Dis. 2013; 20(2): 150‐ 156. 23439374 PMC3582990
  29. [31]Lineva A, Kirchner R, Kienzle E, Kamphues J, Dobenecker B. A pilot study on in vitro solubility of phosphorus from mineral sources, feed ingredients and compound feed for pigs, poultry, dogs and cats. J Anim Physiol Anim Nutr (Berl). 2019; 103: 317‐ 323. 30353593
  30. [32]Heaney RP, Nordin BE. Calcium effects on phosphorus absorption: implications for the prevention and co‐therapy of osteoporosis. J Am Coll Nutr. 2002; 21(3): 239‐ 244. 12074251
  31. [33]Chang AR, Anderson C. Dietary phosphorus intake and the kidney. Annu Rev Nutr. 2017; 37: 321‐ 346. 28613982 PMC5686387
  32. [34]Karp HJ, Vaihia KP, Kärkkäinen MU, et al. Acute effects of different phosphorus sources on calcium and bone metabolism in young women: a whole‐foods approach. Calcif Tissue Int. 2007; 80(4): 251‐ 258. 17401693
  33. [35]Noori N, Sims JJ, Kopple JD, et al. Organic and inorganic dietary phosphorus and its management in chronic kidney disease. Iran J Kidney Dis. 2010; 49(2): 89‐ 100. 20404416
  34. [36]Matsuzaki H, Kikuchi T, Kajita Y, et al. Comparison of various phosphate salts as the dietary phosphorus source on nephrocalcinosis and kidney function in rats. J Nutr Sci Vitaminol (Tokyo). 1999; 45(5): 595‐ 608. 10683811
  35. [37]Coltherd JC, Staunton R, Colyer A, et al. Not all forms of dietary phosphorus are equal: an evaluation of postprandial phosphorus concentrations in the plasma of the cat. Br J Nutr. 2019; 121(3): 270‐ 284. 30420000 PMC6390407

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Authors
Summers, S. C., Stockman, J., Larsen, J. A., Zhang, L., & Rodriguez, A. S.
Affiliations
  • Colorado State University (US)
  • University of California, Davis (US)
Corresponding author
Stockman, Jonathan
Venue
Journal of Veterinary Internal Medicine
Published
2020-01-01
Volume
34
Issue
1
Pages
266-273
ISSN
  • 0891-6640 (ISSN-L)
  • 1939-1676
OpenAlex
W2997678985
Cited by
28
References
0
Citations by year
2026: 4 · 2025: 3 · 2024: 7 · 2023: 2 · 2022: 3 · 2021: 7 · 2020: 2
FWCI
3.95
Type
journal article
Language
en
Open access
Locations
  • Journal of Veterinary Internal Medicine (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • eScholarship (California Digital Library) (submittedVersion)
  • eScholarship (California Digital Library) (submittedVersion, cc-by-nc)
Funders
Winn Feline Foundation
Topics
  • Health Sciences › Veterinary › Small Animals › Veterinary Medicine and Surgery
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Food and Agricultural Sciences
Keywords
cat food, phosphorus, calcium, magnesium, Ca/P ratio, feline kidney disease, feline nutrition, commercial pet food, crude protein, grain-free diet, raw diet, canned food, dry food, pet food regulation
MeSH terms
Animals, Animal Feed, Calcium, Calcium, Dietary, Cats, Diet, Magnesium, Nutritive Value, Phosphorus, Phosphorus, Dietary

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