CoChat
Sign Up
Cited by 49Fungal Infections and StudiesAntifungal resistance and susceptibilityNail Diseases and Treatments

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Cryptococcal disease and the burden of other fungal diseases in Uganda; Where are the knowledge gaps and how can we fill them?

Open access
Parkes‐Ratanshi, R., Achan, B., Kwizera, R., Kambugu, A., Meya, D., Denning, D. W.·2015·Mycoses
DOI 10.1111/myc.12387
Open this paper in CoChat — free accountOpen PDF

Abstract

Summary: The HIV epidemic in Uganda has highlighted Cryptococcus and Candida infections as important opportunistic fungal infections. However, the burden of other fungal diseases is not well described. We aimed to estimate the burden of fungal infections in Uganda. All epidemiological papers of fungal diseases in Uganda were reviewed. Where there is no Ugandan data, global or East African data were used. Recurrent vaginal candidiasis is estimated to occur in 375 540 Uganda women per year; Candida in pregnant women affects up to 651 600 women per year. There are around 45 000 HIV‐related oral and oesophageal candidosis cases per year. There are up to 3000 cases per year of post‐TB chronic pulmonary aspergillosis. There are an estimated 40 392 people with asthma‐related fungal conditions. An estimated 1 300 000 cases of tinea capitis occur in school children yearly in Uganda. There are approximately 800 HIV‐positive adults with Pneumocystis jirovecii pneumonia (PJP) annually and up to 42 000 children with PJP per year. There are an estimated 4000 cryptococcal cases annually. There are an estimated 2.5 million fungal infections per year in Uganda. Cryptococcus and PJP cause around 28 000 deaths in adults and children per year. We propose replicating the model of research around cryptococcal disease to investigate and development management strategies for other fungal diseases in Uganda.

Overview

Integrity signals

Registry

Crossref · 10.1111/myc.12387

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The highest estimated tinea capitis case numbers were in Nigeria (15,581,400), followed by Kenya (1,712,676), Senegal (1,523,700), Uganda (1,300,000), and Tanzania (420,000).

    “The highest estimated cases were from Nigeria (15,581,400 cases) [62] followed by Kenya with 1,712,676 cases [75], with Senegal, Uganda and Tanzania reporting 1,523,700, 1,300,000 and 420,000 cases respectively [78,122,133].”

    From Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision (2017) · cites this paper as [122]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 74

  1. 10.1186/1471-2334-10-47 · DOI
  2. 10.1371/journal.pntd.0003225 · DOI
  3. 10.1371/journal.pone.0056446 · DOI
  4. 10.2174/1570162X11311020007 · DOI
  5. 10.1099/jmm.0.000020 · DOI
  6. Oladele RO, 2014, Burden of serious fungal infection in Nigeria, West Afr J Med, 33, 107
  7. 10.1097/00004397-200201000-00010 · DOI
  8. 10.1016/S0140-6736(07)60917-9 · DOI · Paper page
  9. 10.1136/sti.2005.014845 · DOI
  10. 10.4104/pcrj.2011.00027 · DOI
  11. 10.1186/s12887-014-0285-4 · DOI
  12. 10.3322/canjclin.55.2.74 · DOI
  13. 10.3109/13693786.2010.509138 · DOI
  14. 10.4314/eamj.v86i2.46934 · DOI
  15. 10.1097/QAD.0b013e328322ffac · DOI
  16. 10.1016/S1473-3099(11)70245-6 · DOI
  17. 10.1186/1471-2393-11-18 · DOI
  18. 10.1097/LGT.0b013e318287aced · DOI
  19. 10.3324/haematol.2011.044636 · DOI
  20. 10.1016/S0954-6111(12)70016-1 · DOI · Paper page
  21. 10.1086/318483 · DOI
  22. 10.1093/clinids/23.3.608 · DOI
  23. 10.1126/scitranslmed.3004404 · DOI · Paper page
  24. Worodria W, 2003, Causes of lower respiratory infection in HIV‐infected Ugandan adults who are sputum AFB smear‐negative, Int J Tuberc Lung Dis, 7, 117
  25. 10.1097/QAI.0b013e3181eb611a · DOI
  26. 10.1016/j.diagmicrobio.2011.10.009 · DOI
  27. 10.1371/journal.pone.0082257 · DOI
  28. 10.1371/journal.pone.0068445 · DOI
  29. Rudan I, 2013, Epidemiology and etiology of childhood pneumonia in 2010: estimates of incidence, severe morbidity, mortality, underlying risk factors and causative pathogens for 192 countries, J Glob Health, 3, 010401
  30. 10.1097/00002030-200201040-00013 · DOI
  31. 10.1111/j.1651-2227.2001.tb00270.x · DOI
  32. 10.1179/146532808X375404 · DOI
  33. Morrow BM, 2010, Pneumocystis pneumonia in South African children with and without human immunodeficiency virus infection in the era of highly active antiretroviral therapy, Pediatr Infect Dis J, 29, 535, 10.1097/INF.0b013e3181ce871e · DOI
  34. 10.1097/INF.0b013e3181fcabe4 · DOI
  35. Cox JA, 2010, Autopsy causes of death in HIV‐positive individuals in sub‐Saharan Africa and correlation with clinical diagnoses, AIDS Rev, 12, 183
  36. 10.1051/parasite/2011183219 · DOI
  37. 10.1086/507095 · DOI
  38. 10.1111/j.1365-3156.2007.01874.x · DOI
  39. 10.1086/587667 · DOI
  40. Wilson AM, 1965, The aetiology of mycetoma in uganda compared with other african countries, East Afr Med J, 42, 182
  41. 10.1007/BF00437587 · DOI
  42. 10.1001/archderm.1996.03890310107018 · DOI
  43. 10.1080/00362176485190541 · DOI
  44. Raselli C, 2013, Histoplasmosis ‐ an unusual African souvenir, Dtsch Med Wochenschr, 138, 313
  45. Mutesasira L, 1968, Disseminated histoplasmosis duboisii in Uganda, East Afr Med J, 45, 687
  46. Mugerwa JW, 1977, Histoplasma infection in Uganda, East Afr Med J, 54, 227
  47. Bezjak V, 1971, Histoplasmin tests in Ugandan sawmill workers, Trop Geogr Med, 23, 71
  48. Bezjak V, 1970, Prevalence of skin sensitivity to histoplasmin and coccidioidin in varous Ugandan populations, Am J Trop Med Hyg, 19, 664, 10.4269/ajtmh.1970.19.664 · DOI
  49. 10.1111/jtm.12012 · DOI
  50. 10.3109/09286586.2011.595041 · DOI
  51. 10.1038/eye.1998.45 · DOI
  52. 10.1093/ije/27.4.698 · DOI
  53. 10.1097/00002030-200205030-00009 · DOI
  54. 10.1053/jinf.2000.0697 · DOI
  55. 10.1086/516372 · DOI
  56. 10.1258/0049475053001967 · DOI
  57. 10.1086/593194 · DOI
  58. 10.1093/ofid/ofu070 · DOI
  59. 10.1086/597262 · DOI
  60. 10.1086/655143 · DOI
  61. 10.1097/QAI.0b013e31824c837e · DOI
  62. 10.1371/journal.pone.0101459 · DOI
  63. 10.1371/journal.pone.0103156 · DOI
  64. 10.3201/eid2001.130906 · DOI
  65. 10.1093/cid/cit641 · DOI
  66. 10.1371/journal.pmed.1000384 · DOI
  67. 10.1086/655785 · DOI
  68. 10.1093/infdis/jiu664 · DOI
  69. 10.1016/j.mmcr.2014.05.001 · DOI
  70. 10.1056/NEJMoa1312884 · DOI
  71. 10.1093/infdis/jiv067 · DOI
  72. 10.1093/infdis/jit435 · DOI
  73. Wiesner DL, 2015, Cryptococcal genotype influences immunologic response and human clinical outcome after meningitis, PLoS Negl Trop Dis, 9, e0003847
  74. 10.1093/jac/dkp451 · DOI

Cited by

Sorted by citations

Metadata

Authors
Parkes‐Ratanshi, R., Achan, B., Kwizera, R., Kambugu, A., Meya, D., & Denning, D. W.
Affiliations
  • Infectious Diseases Institute Kampala Uganda
  • Makerere University (UG)
  • Infectious Diseases Institute (UG)
  • Manchester Academic Health Science Centre (GB)
ORCID
Venue
Mycoses
Publisher
Wiley
Published
2015-10
Volume
58
Issue
S5
Pages
85-93
ISSN
  • 0027-5557 (ISSN-L)
  • 0933-7407
  • 1439-0507
DOI
10.1111/myc.12387
OpenAlex
W1950009220
Cited by
49
References
3
Citations by year
2026: 1 · 2025: 3 · 2024: 8 · 2023: 1 · 2022: 6 · 2021: 8 · 2020: 6 · 2019: 6 · 2018: 1 · 2017: 6 · 2016: 3
FWCI
0.43
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 8 d)
Locations
  • Mycoses (publishedVersion)
  • PubMed (publishedVersion)
  • Research Explorer (The University of Manchester) (submittedVersion)
Funders
  • National Institute of Allergy and Infectious Diseases
  • Medical Research Council
Topics
  • Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Health Sciences › Medicine › Dermatology › Nail Diseases and Treatments
Keywords
fungal infection, cryptococcosis, HIV-associated opportunistic infections, candidiasis, recurrent vaginal candidiasis, oral candidiasis, esophageal candidiasis, tinea capitis, Pneumocystis carinii pneumonia, disease burden estimation, Uganda, knowledge gaps
MeSH terms
Aspergillosis, Candidiasis, Cryptococcosis, Female, Humans, Male, Mycoses, Pregnancy, Pregnancy Complications, Infectious, Uganda, Vulvovaginitis, AIDS-Related Opportunistic Infections, Cost of Illness

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review