Endocrine‐disrupting chemicals and obesity risk: A review of recommendations for obesity prevention policies
Abstract
Summary: Emerging evidence indicates that industrially produced endocrine‐disrupting chemicals (EDCs) may be as obesogenic as poor dietary patterns and should be considered in obesity prevention policies. The authors conducted two reviews: (a) a systematic search of four electronic databases for papers published since January 2010 to identify the policy recommendations contained in scientific reviews of EDC exposure and obesity risk and (b) a narrative review of obesity policy documents published since January 2012 to identify the recommendations of national and international agencies. A search of four electronic databases found 63 scientific reviews with policy recommendations, of which 26 suggested individual responsibility to avoid exposure, 11 suggested medical interventions to counter the effects of exposure, and 42 suggested regulatory control of hazardous chemicals. Of sixty policy documents examined, six mentioned pollutants as a possible risk factor for obesity, and only one made explicit reference to strategies for reducing exposure to EDCs. The UN Sustainable Development Goals include targets to prevent ill health from hazardous chemicals (Targets 3.9 and 12.4) and to remove unsafe industrial chemicals from the environment (Targets 6.3, 11.6, 12.4, and 14.1). The authors suggest these should be explicitly linked to World Health Assembly targets to halt the rise in obesity.
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Environmental pollutants might also contribute to obesity, although those mechanisms are largely undefined.
“Environmental pollutants might also contribute to obesity, although those mechanisms are largely undefined.82,83”
From Definition and diagnostic criteria of clinical obesity (2025) · cites this paper as [82]
Cites
Joint international consensus statement for ending stigma of obesity
Rubino, F., Puhl, R. M., Cummings, D. E., Eckel, R. H., Ryan, D. H., Mechanick, J. I., Nadglowski, J., Ramos Salas, X., Schauer, P. R., Twenefour, D., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0803-x · Cited by 1,152 · see citing works
Qin, P., Li, Q., Zhao, Y., Chen, Q., Sun, X., Liu, Y., Li, H., Wang, T., Chen, X., Zhou, Q., et al. (2020) · European Journal of Epidemiology · doi:10.1007/s10654-020-00655-y · Cited by 323 · see citing works
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Definition and diagnostic criteria of clinical obesity
Rubino, F., Cummings, D. E., Eckel, R. H., Cohen, R. V., Wilding, J. P. H., Brown, W. A., Stanford, F. C., Batterham, R. L., Farooqi, I. S., Farpour-Lambert, N. J., et al. (2025) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(24)00316-4 · Cited by 1,811 · see citing works
- Authors
- Lobstein, T., & Brownell, K. D.
- Affiliations
- The University of Sydney (AU)
- Duke University (US)
- Corresponding author
- Lobstein, Tim
- ORCID
- Lobstein, Tim
- Venue
- Obesity Reviews
- Publisher
- Wiley
- Published
- 2021-08-18
- Volume
- 22
- Issue
- 11
- Pages
- e13332-e13332
- ISSN
- 1467-7881 (ISSN-L)
- 1467-789X
- OpenAlex
- W3193453578
- Cited by
- 49
- References
- 2
- Citations by year
- 2026: 6 · 2025: 15 · 2024: 11 · 2023: 8 · 2022: 7 · 2021: 2
- FWCI
- 0.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Obesity Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- endocrine disruptors, obesity, obesity prevention policy, chemical regulation, exposure reduction, industrial chemicals, Sustainable Development Goals, health policy recommendations
- MeSH terms
- Environmental Pollutants, Humans, Obesity, Endocrine Disruptors, Policy
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