The pga gene cluster in A ggregatibacter actinomycetemcomitans is necessary for the development of natural competence in Ca 2+‐promoted biofilms

Summary Natural competence is the ability of bacteria to incorporate extracellular DNA into their genomes. This competence is affected by a number of factors, including Ca 2+ utilization and biofilm formation. As bacteria can form thick biofilms in the presence of extracellular Ca 2+ , the additi…