Neural basis of major depressive disorder: Beyond monoamine hypothesis

Boku, Shuken, Nakagawa, Shin, Toda, Hiroyuki, Hishimoto, Akitoyo·2018·Psychiatry and Clinical Neurosciences

Cited by (403)

Items 101–200 of 403

  1. Association of bone mineral density and depression in different bone sites and ages: A meta‐analysis
    Shiyi Yuan, Jianjun Chen, Li Zeng, Chanjuan Zhou, Shenrun Yu, Liang Fang · 2021 · Food Science & Nutrition
  2. Memory and processing speed impairments in first-episode drug-naïve patients with major depressive disorder
    Yongbo Hu, Jin Li, Youjin Zhao, Zaiquan Dong, Peiyuan Qiu, Shujuan Yang, Haizhen Xu, Weihong Kuang, Qiyong Gong · 2022 · Journal of Affective Disorders
  3. TCA and SSRI Antidepressants Exert Selection Pressure for Efflux-Dependent Antibiotic Resistance Mechanisms in Escherichia coli
    Jin Ou, Paul Elizalde, Hao‐Bo Guo, Hong Qin, Brian T. D. Tobe, John S. Choy · 2022 · mBio
  4. The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users
    Megan J. Shram, Jack E. Henningfield, Glen Apseloff, Charles W. Gorodetzky, Sara De Martin, Frank L. Vocci, Frank L. Sapienza, Thomas R. Kosten, Jeff Huston, August R. Buchhalter et al. · 2023 · Translational Psychiatry
  5. Biological Effects and Biomedical Applications of Areca Nut and Its Extract
    Ting Tong, Aiqing Xu, Shuhua Tan, Hengzhi Jiang, Lixin Liu, Senwen Deng, Haihua Wang · 2024 · Pharmaceuticals
  6. Astrocytic plasticity at the dorsal dentate gyrus on an animal model of recurrent depression
    Ana Rita Machado-Santos, Nuno Dinis Alves, Bruna Araújo, Joana Sofia Correia, Patrícia Patrício, António Mateus‐Pinheiro, Eduardo Loureiro‐Campos, João Miguel Bessa, Nuno Sousa, Luísa Pinto · 2019 · Neuroscience
  7. The Diagnostic Value of the Combination of Serum Brain-Derived Neurotrophic Factor and Insulin-Like Growth Factor-1 for Major Depressive Disorder Diagnosis and Treatment Efficacy
    Alexandra S. Troyan, Oleg A. Levada · 2020 · Frontiers in Psychiatry
  8. Phosphodiesterase-5 inhibitors: Shedding new light on the darkness of depression?
    Eduardo Pereira Duarte-Silva, Adriano José Maia Chaves Filho, Tatiana Barichello, João Quevedo, Danielle S. Macêdo, Christina Alves Peixoto · 2019 · Journal of Affective Disorders
  9. Anti-depressive-like effect of monoterpene trans-anethole via monoaminergic pathways
    Salah-Aldin Hassanzadeh, Saeid Abbasi-Maleki, Zahra Mousavi · 2022 · Saudi Journal of Biological Sciences
  10. Different depression: motivational anhedonia governs antidepressant efficacy in Huntington’s disease
    Duncan James McLauchlan, Thomas Matthew Lancaster, David Craufurd, David E.J. Linden, Anne Rosser · 2022 · Brain Communications
  11. Liraglutide and Naringenin relieve depressive symptoms in mice by enhancing Neurogenesis and reducing inflammation
    Yara S. Abdelkawy, Mona Elharoun, Eman Sheta, Ihab Talat Abdel-Raheem, Hisham A. Nematalla · 2024 · European Journal of Pharmacology
  12. Creatine and taurine mixtures alleviate depressive-like behaviour in Drosophila melanogaster and mice via regulating Akt and ERK/BDNF pathways
    Suhyeon Kim, Ki‐Bae Hong, Singeun Kim, Hyung Joo Suh, Kyungae Jo · 2020 · Scientific Reports
  13. Discovery of Novel and Potent N-Methyl- d -aspartate Receptor Positive Allosteric Modulators with Antidepressant-like Activity in Rodent Models
    Zhongtang Li, Guanxing Cai, Fang Fan, Wenchao Li, Minghua Fan, Jingjing Lian, Yinli Qiu, Xiangqing Xu, Xuehui Lv, Yiyan Li et al. · 2021 · Journal of Medicinal Chemistry
  14. The Association Between Antidepressant Effect of SSRIs and Astrocytes: Conceptual Overview and Meta‐analysis of the Literature
    Beina Chen, Manman Zhang, Ming Ji, Wenliang Gong, Binjie Chen, Robert Zorec, Matjaž Stenovec, Alexei Verkhratsky, Baoman Li · 2021 · Neurochemical Research
  15. Continuous Ingestion of Lacticaseibacillus rhamnosus JB-1 during Chronic Stress Ensures Neurometabolic and Behavioural Stability in Rats
    Agata Chudzik, Tymoteusz Słowik, Katarzyna Kochalska, Anna Pankowska, Artur Łazorczyk, Marta Andres‐Mach, Radosław Rola, Greg J. Stanisz, Anna Orzyłowska · 2022 · International Journal of Molecular Sciences
  16. Altered coordination between frontal delta and parietal alpha networks underlies anhedonia and depressive rumination in major depressive disorder
    Zenas C. Chao, Daniel G. Dillon, Yi-Hung Liu, Elyssa M Barrick, Chien‐Te Wu · 2022 · Journal of Psychiatry and Neuroscience
  17. Running from stress: a perspective on the potential benefits of exercise-induced small extracellular vesicles for individuals with major depressive disorder
    R. Khoury, C. Nagy · 2023 · Frontiers in Molecular Biosciences
  18. Radix Scutellariae Ameliorates Stress-Induced Depressive-Like Behaviors via Protecting Neurons through the TGFβ3-Smad2/3-Nedd9 Signaling Pathway
    Fan Zhao, Chenyiyu Zhang, Xiao Ying Dong, Weihua Zhang, Liping Zhou, Simeng Gu, Rong Qu · 2020 · Neural Plasticity
  19. Efficacy, Tolerability, and Safety of Toludesvenlafaxine for the Treatment of Major Depressive Disorder—A Narrative Review
    Octavian Vasiliu · 2023 · Pharmaceuticals
  20. Antidepressant effects of creatine on amyloid β1–40-treated mice: The role of GSK-3β/Nrf2 pathway
    Julia Macedo Rosa, Francis L. Pazini, Mauricio Peña Cunha, André Roberto Da Silva Colla, Luana Meller Manosso, Gianni Mancini, Ana Cristina Guerra Souza, Andreza Fabro De Bem, Rui Daniel Prediger, Ana Lúcia S. Rodrigues · 2018 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  21. Involvement of the Dorsal Hippocampus 5-HT1A Receptors in the Regulation of Depressive-Like Behaviors in Hemiparkinsonian Rats
    Yi-Fan Jiang, Jian Liu, Jie Yang, Yuan Guo, Wei Ming Hu, Jin Zhang, Xue-Mei La, Wen Xie, Huisheng Wang, Li Zhang · 2020 · Neuropsychobiology
  22. Olfactory loss is a predisposing factor for depression, while olfactory enrichment is an effective treatment for depression
    Michael Leon, Cynthia C. Woo · 2022 · Frontiers in Neuroscience
  23. Reviewing the role of gut microbiota in the pathogenesis of depression and exploring new therapeutic options
    Wenjie Han, Na Wang, Mengzhen Han, Meng Ban, Tao Sun, Junnan Xu · 2022 · Frontiers in Neuroscience
  24. Differentiated HT22 cells as a novel model for in vitro screening of serotonin reuptake inhibitors
    Juhee Lim, Yeojin Bang, Kyeong‐Man Kim, Hyun Jin Choi · 2023 · Frontiers in Pharmacology
  25. Association between blood manganese levels and depressive symptoms among US adults: A nationally representative cross-sectional study
    Shunli Jiang, Mingjia Sun, Xinyong Zhou, Yaru Xu, Habib Ullah, Xinpeng Niu, Chen Feng, Qin Feng Gao · 2023 · Journal of Affective Disorders
  26. Mode of Action of Shan‐Zhu‐Yu (Cornus officinalis Sieb. et Zucc.) in the Treatment of Depression Based on Network Pharmacology
    Ping Liu, Ping Yang, Lan Zhang · 2020 · Evidence-based Complementary and Alternative Medicine
  27. Brain Functional Network and Amino Acid Metabolism Association in Females with Subclinical Depression
    Shanguang Zhao, Selina Khoo, Siew‐Cheok Ng, Aiping Chi · 2022 · International Journal of Environmental Research and Public Health
  28. Prevention and treatment of natural products from Traditional Chinese Medicine in depression: Potential targets and mechanisms of action
    Ming‐Chao He, Rui Feng, Jing Wang, Shihui Xia, Yongjun Wang, Yan Zhang · 2022 · Frontiers in Aging Neuroscience
  29. The antidepressant effect of nucleus accumbens deep brain stimulation is mediated by parvalbumin-positive interneurons in the dorsal dentate gyrus
    Hong Zhou, Jiayu Zhu, Jie Jia, Wei Xiang, Hualing Peng, Yuejin Zhang, Bo Liu, Yangling Mu, Yisheng Lu · 2022 · Neurobiology of Stress
  30. Efficacy and Safety of Esmethadone (REL-1017) in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants
    Maurizio Fava M. D, Stephen M. Stahl, Luca Pani, Sara De Martin, Andrew J. Cutler, Vladimir Maletic, Charles W. Gorodetzky, Frank J. Vocci, Frank L. Sapienza, Thomas R. Kosten et al. · 2024 · The Journal of Clinical Psychiatry
  31. Role of SIRT1-mediated synaptic plasticity and neurogenesis: Sex-differences in antidepressant-like efficacy of catalpol
    Xiaohui Wu, Yueyue Zhang, Junming Wang, Lingyu Qin, Yamin Li, Qingwen He, Tianzhu Zhang, Yanmei Wang, Lingling Song, Lijie Ji et al. · 2024 · Phytomedicine
  32. Is occipital bending a structural biomarker of risk for depression and sensitivity to treatment?
    Karen Fullard, Jerome Joseph Maller, Thomas Welton, Matthew Lyon, Evian Gordon, Stephen H. Koslow, Stuart M. Grieve · 2019 · Journal of Clinical Neuroscience
  33. LIMK1/2 in the mPFC Plays a Role in Chronic Stress-Induced Depressive-Like Effects in Mice
    Tingting Gao, Yuan Wang, Ling Liu, Jinliang Wang, Yingjie Wang, Wei Guan, Tingting Chen, Jie Zhao, Bo Jiang · 2020 · The International Journal of Neuropsychopharmacology
  34. The relationship between plasma cytokine levels and antidepressant response in patients with first-episode major depressive disorder
    Xiaofeng Lan, Yanling Zhou, Fengchun Wu, Kai Wu, Yanni Zhan, Chengyu Wang, Wei Zheng, Min Yu, Xiurong Deng, Yuping Ning · 2021 · Journal of Affective Disorders
  35. The sour side of vitamin C might mediate neuroprotective, anticonvulsive and antidepressant-like effects
    Udo Bonnet · 2019 · Medical Hypotheses
  36. Brain matrix metalloproteinase-9 activity is altered in the corticosterone mouse model of depression
    Silvia Breviario, Júlia Senserrich, Eva Florensa-Zanuy, Emilio Garro-Martínez, Álvaro Díaz, Elena Castro, Ángel Pazos, Fuencisla Pilar-Cuéllar · 2022 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  37. Testosterone Replacement Therapy in the Treatment of Depression
    Danyon J. Anderson, Parsia Vazirnia, Catherine A. Loehr, Whitney Sternfels, Jamal J. Hasoon, Omar Viswanath, Alan D. Kaye, Ivan Urits · 2022 · Health Psychology Research
  38. FBXL20 promotes synaptic impairment in depression disorder via degrading vesicle-associated proteins
    Wenjing Wang, Ye Li, Liyan Wang, Xiao Chen, Tian Lan, Changmin Wang, Shihong Chen, Shuyan Yu · 2024 · Journal of Affective Disorders
  39. The darkness and the light: diurnal rodent models for seasonal affective disorder
    Anusha Shankar, Cory T. Williams · 2021 · Disease Models & Mechanisms
  40. Possible antidepressant mechanism of acupuncture: targeting neuroplasticity
    Ning Xu, Yue He, Yong-Nan Wei, Lu Bai, Long Wang · 2025 · Frontiers in Neuroscience
  41. Design, Synthesis, and Activity Evaluation of Fluorine-Containing Scopolamine Analogues as Potential Antidepressants
    Le Wang, Xushuo Zhu, Bo Wang, Yijing Wang, Mengqi Wang, Shuping Yang, Chenhe Su, Junbiao Chang, Bo Zhu · 2024 · Journal of Medicinal Chemistry
  42. Cyclooxygenase-2 inhibitors alleviated depressive and anxious-like behaviors in mice exposed to lipopolysaccharide: Involvement of oxidative stress and neuroinflammation
    Daniel Moreira Alves da Silva, Iardja Stéfane Lopes, João Victor Souza Oliveira, Manuel Alves Santos Júnior, Manoela de Oliveira Rebouças, José Tiago Valentim, Larice de Carvalho Vale, Victor Celso Cavalcanti Capibaribe, Michele Albuquerque Jales de Carvalho, Pedro Éverson Alexandre de Aquino et al. · 2024 · Pharmacology Biochemistry and Behavior
  43. Chirality in Modern Antidepressants: A Comprehensive Review of Stereochemical Impacts on Pharmacology and Therapeutics
    Gabriel Hancu, Alexandra Uilăcan, Nicoleta Mirela Blebea · 2024 · Drugs and Drug Candidates
  44. The Antidepressant Effect of Resveratrol Is Related to Neuroplasticity Mediated by the ELAVL4-Bdnf mRNA Pathway
    Hailong Ge, Lujia Si, Chen Li, Junjie Huang, Limin Sun, Lan Wu, Yinping Xie, Ling Xiao, Gaohua Wang · 2025 · International Journal of Molecular Sciences
  45. A single administration of Neurotropin reduced the elongated immobility time in the forced swimming test of rats exposed to repeated cold stress
    Teruaki Nasu, Asako Kubo, Luis F. Queme, Kazue Mizumura · 2019 · Behavioural Pharmacology
  46. Short-term memory impairment following recovery from systemic inflammation induced by lipopolysaccharide in mice
    Kohei Morimoto, Shu Watanuki, Ryota Eguchi, Taisuke Kitano, Ken‐ichi Otsuguro · 2023 · Frontiers in Neuroscience
  47. The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment
    Susu Qu, Xiangyu Zhou, Zhicheng Wang, Wei Yi, Han Zhou, Xinshuang Zhang, Qingjie Zhu, Yanmin Wang, Quanjun Yang, Likun Jiang et al. · 2023 · Molecular Psychiatry
  48. Interplay of G-proteins and Serotonin in the Neuroimmunoinflammatory Model of Chronic Stress and Depression: A Narrative Review
    Evgeni Gusev, Alexey Sarapultsev · 2023 · Current Pharmaceutical Design
  49. Depressive symptoms as predictors of visual memory deficits in middle-age
    Marjo Taivalantti, Jennifer H. Barnett, Anu‐Helmi Halt, Jari Koskela, JUHA P. AUVINEN, Markku Timonen, Marjo‐Riitta Järvelin, Juha M. Veijola · 2019 · Journal of Affective Disorders
  50. Cognitive dysfunction in mice lacking proper glucocorticoid receptor dimerization
    Kelly Van Looveren, Michiel Van Boxelaere, Zsuzsanna Callaerts‐Vegh, Claude Libert · 2019 · PLoS ONE
  51. Gut Hormones as Potential Therapeutic Targets or Biomarkers of Response in Depression: The Case of Motilin
    Ravi Philip Rajkumar · 2021 · Life
  52. From Monoamines to Systems Psychiatry: Rewiring Depression Science and Care (1960s–2025)
    Masaru Tanaka · 2025 · Biomedicines
  53. The olfactory bulbectomy disease model: A Re-evaluation.
    David M. Coppola, R. Parrish Waters · 2021 · Physiology & Behavior
  54. MiR-184-3p in the paraventricular nucleus participates in the neurobiology of depression via regulation of the hypothalamus-pituitary-adrenal axis
    Dawei Xu, Wei-Yu Li, Tian-Shun Shi, Chengniu Wang, Si-Yi Zhou, Wei Liu, Weijia Chen, Bao-Lun Zhu, Hao Fei, Dong-dong Cheng et al. · 2024 · Neuropharmacology
  55. Co-administration of midazolam and psilocybin: differential effects on subjective quality versus memory of the psychedelic experience
    Christopher R. N. Nicholas, Matthew I. Banks, Richard C. Lennertz, Cody J. Wenthur, Bryan M. Krause, Brady A. Riedner, Richard Smith, Paul R. Hutson, Christina J. Sauder, John D. Dunne et al. · 2024 · Translational Psychiatry
  56. SUMOylation and Major Depressive Disorder
    Seok-Won Jeoung, Hyun-Sun Park, Zae Young Ryoo, Dong‐Hyung Cho, Hyun‐Shik Lee, Hong‐Yeoul Ryu · 2022 · International Journal of Molecular Sciences
  57. Investigating the potential anti-depressive mechanisms of statins: a transcriptomic and Mendelian randomization analysis
    Jiayue-Clara Jiang, Chenwen Hu, Andrew Mark McIntosh, Sonia H Shah · 2023 · Translational Psychiatry
  58. New Insights Into the Pivotal Role of CREB-Regulated Transcription Coactivator 1 in Depression and Comorbid Obesity
    Clara Rossetti, Antoine Cherix, Laetitia Guiraud, Jean‐René Cardinaux · 2022 · Frontiers in Molecular Neuroscience
  59. The role of GABA, glutamate, and Glx levels in treatment of major depressive disorder: A systematic review and meta-analysis
    Kate Godfrey, Hannah M. Douglass, David Erritzøe, Suresh D Muthukumaraswamy, David Nutt, Rachael L. Sumner · 2025 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  60. Task-Related Neural Activation Abnormalities in Patients with Remitted Major Depressive Disorder: A Coordinate-Based Meta-Analysis
    Zuxing Wang, Zhili Zou, Jun Feng Xiao, Peijia Wang, Yuanyuan Luo, Wenjiao Min, Ying He, Cui Yuan, Yihan Su, Chenghui Yang et al. · 2022 · Neuroscience & Biobehavioral Reviews
  61. The potential role of gray matter volume differences in the association between smoking and depression: A narrative review
    Margot P. van de Weijer, Jentien M. Vermeulen, Anouk Schrantee, Marcus Robert Munafo, Karin J. H. Verweij, Jorien L. Treur · 2023 · Neuroscience & Biobehavioral Reviews
  62. Neuroprotective effects of Gypenosides: A review on preclinical studies in neuropsychiatric disorders
    Gengfan Liang, Yu Zhao Lee, Audrey Siew Foong Kow, Qi Long Lee, Luis Wei Cheng Lim, Rohana Yusof, Chau Ling Tham, Yu‐Cheng Ho, Ming Tatt Lee · 2024 · European Journal of Pharmacology
  63. Hippocampal subregion volume in high-risk offspring is associated with increases in depressive symptoms across the transition to adolescence
    Samantha Q Hubachek, Morgan Botdorf, Tracy Riggins, Hoi-Chung Leong, Daniel N. Klein, Lea Rose Dougherty · 2020 · Journal of Affective Disorders
  64. Development of Reward Circuitry During Adolescence: Depression, Social Context, and Considerations for Future Research on Disparities in Sexual and Gender Minority Youth
    Kristen Eckstrand, Carly J. Lenniger, Erika E. Forbes · 2022 · Annual Review of Developmental Psychology
  65. GABAB receptor intracellular signaling: novel pathways for depressive disorder treatment?
    Maciej Korczak, Przemysław Norbert Kurowski, Anna Leśniak, Alfhild Grönbladh, Anna Filipowska, Magdalena Bujalska‐Zadrożny · 2020 · European Journal of Pharmacology
  66. Corticosterone as a potential confounding factor in delineating mechanisms underlying Ketamine’s rapid antidepressant actions
    Wegman-Points, Lauren, Pope, Brock, Zobel-Mask, Allison, Winter, Lori, Wauson, Eric, Duric, Vanja, Yuan, Li-Lian · 2020 · Frontiers in Pharmacology
  67. Effects of Current Psychotropic Drugs on Inflammation and Immune System
    Shvetank Bhatt, Arghya Kusum Dhar, Malay K. Samanta, Ashish Suttee · 2023 · Advances in experimental medicine and biology
  68. Sodium-Glucose Cotransporter-2 Inhibitors in Depression
    David T. Liebers, Wataru Ebina, Dan Vlad Iosifescu · 2023 · Harvard Review of Psychiatry
  69. Association between NTRK2 Polymorphisms, Hippocampal Volumes and Treatment Resistance in Major Depressive Disorder
    Marco Paolini, Lidia Fortaner-Uyà, Cristina Lorenzi, Sara Spadini, Melania Maccario, Raffaella Zanardi, Cristina Colombo, Sara Poletti, Francesco Benedetti · 2023 · Genes
  70. A statistical method for image-mediated association studies discovers genes and pathways associated with four brain disorders
    Jingni He, Lilit Antonyan, Harold Zhu, Karen Ardila, Qing Li, David Enoma, William Zhang, Andy Liu, Thierry Chekouo, Bo Cao et al. · 2023 · The American Journal of Human Genetics
  71. The association between gray matter volume in the hippocampal subfield and antidepressant efficacy mediated by abnormal dynamic functional connectivity
    Changxiao Kuai, Jiayong Pu, Donglin Wang, Zhonglin Tan, Yan Wang, Shao‐Wei Xue · 2024 · Scientific Reports
  72. The Role of HSP90 Molecular Chaperones in Depression: Potential Mechanisms
    Xuyuan Fan, Lei Sun, Ye Qin, Yuan Liu, Shusheng Wu, Longfei Du · 2024 · Molecular Neurobiology
  73. A review of diffusion MRI in mood disorders: mechanisms and predictors of treatment response
    Noor Al‐Sharif, Artemis Zavaliangos‐Petropulu, Katherine L. Narr · 2024 · Neuropsychopharmacology
  74. N-methyl-D-aspartate Receptors and Depression: Linking Psychopharmacology, Pathology and Physiology in a Unifying Hypothesis for the Epigenetic Code of Neural Plasticity
    Stefano Comai, Sara De Martin, Andrea Mattarei, Clotilde Guidetti, Marco Pappagallo, Franco B. Folli, Andrea Alimonti, Paolo L. Manfredi · 2024 · Pharmaceuticals
  75. AMPA receptor diffusional trapping machinery as an early therapeutic target in neurodegenerative and neuropsychiatric disorders
    Daniel Choquet, Patricio Opazo, Hongyu Zhang · 2025 · Translational Neurodegeneration
  76. Reserpine-Induced Depression and Other Neurotoxicity: A Monoaminergic Hypothesis
    Manoj Govindarajulu, Tharanath Shankar, Shriya Patel, Mary Fabbrini, Amulya Manohar, Sindhu Ramesh, Prashanth Boralingaiah, Sreelakshmi Sharma, Randall C. Clark, Jack DeRuiter et al. · 2021 · Springer eBooks
  77. An overview of the behavioral, neurobiological and morphological effects of topiramate in rats exposed to chronic unpredictable mild stress
    Sule Aydın, Zeynep Gul Yazici, Cansu KILIÇ, Birce Ercelen Ozozturk, Fatma Sultan Kılıç · 2021 · European Journal of Pharmacology
  78. Abnormal Dynamic Functional Connectivity of the Left Rostral Hippocampus in Predicting Antidepressant Efficacy in Major Depressive Disorder
    Shao‐Wei Xue, Changxiao Kuai, Yang Xiao, Lei Zhao, Zhihui Lan · 2022 · Psychiatry Investigation
  79. Hypoxia-inducible Factor Regulates Ten-eleven Translocated Methylcytosine Dioxygenase 1-c-Myc Binding Involved in Depression-like Behavior in Prenatal Hypoxia Offspring
    Hongtao Zeng, Bin Wei, Jingliu Liu, Likui Lu, Ling‐Jun Li, Bin Wang, Miao Sun · 2022 · Neuroscience
  80. Clozapine increases macrophage migration inhibitory factor (MIF) expression via increasing histone acetylation of MIF promoter in astrocytes
    Satoshi Okazaki, Shuken Boku, Ikuo Otsuka, Tadasu Horai, Atsushi Kimura, Naofumi Shimmyo, Naruhisa Yamaki, Akitoyo Hishimoto · 2021 · Journal of Psychiatric Research
  81. Exercise as a Potential Therapeutic Strategy to Target the Clinical Link Between Depression and Alzheimer’s Disease: A Narrative Review
    Elissa Freberg, Giulio Taglialatela · 2022 · Journal of Alzheimer s Disease
  82. Binding Affinity and Mechanisms of Potential Antidepressants Targeting Human NMDA Receptors
    Simin Ye, Yanqiang Han, Zhiyun Wei, Jinjin Li · 2023 · Molecules
  83. Potential Neuroprotective Effects of Alpinia officinarum Hance (Galangal): A Review
    Izzat Zulhilmi Abd Rahman, Siti Hajar Adam, Adila A. Hamid, Mohd Helmy Mokhtar, Ruslinda Mustafar, Mohd Izhar Ariff Mohd Kashim, Ami Febriza, Nur Izzati Mansor · 2024 · Nutrients
  84. Design of anti-depressant phosphodiester amino acidic Keap1-Nrf2 protein-protein interaction inhibitors
    Yi Sun, Jue Wang, Wenxin Ding, Qingqing Qin, Rui Wang, Ruizhi Yu, Jianyu Yan, Ruilin Hou, Guodong Liu, Xiangming Cai et al. · 2025 · Redox Biology
  85. Modulating depression through the gut–brain axis: the role of gut microbiota in therapeutic interventions
    Muhammad Muzammil Nazir, Warisha Ghaffar, Ghanva Mustafa, Saira Saeed, Muhammad Umar Ijaz, Asma Ashraf · 2025 · Naunyn-Schmiedeberg s Archives of Pharmacology
  86. Ketamine for Treatment-Resistant Depression: a New Advocate
    Rodrigo Pérez‐Esparza · 2018 · Revista de investigaci�n Cl�nica
  87. ATP and repetitive electric stimulation increases leukemia inhibitory factor expression in astrocytes: A potential role for astrocytes in the action mechanism of electroconvulsive therapy
    Soichiro Maruyama, Shuken Boku, Satoshi Okazaki, Hiroki Kikuyama, Yoshito Mizoguchi, Akira Monji, Ikuo Otsuka, Ichiro Sora, Tetsufumi Kanazawa, Akitoyo Hishimoto et al. · 2020 · Psychiatry and Clinical Neurosciences
  88. Cerebrospinal fluid proteomics reveal potential protein targets of JiaWeiSiNiSan in preventing chronic psychological stress damage
    Hanzhang Wang, Wu-Long Luo, Ning-Xi Zeng, Huizhen Li, Ling Li, Can Yan, Lili Wu · 2021 · Pharmaceutical Biology
  89. Developmental and behavioral toxicity assessment of opicapone in zebrafish embryos
    Zhengkang Su, Kaiyu Guan, Yunbin Liu, Hai Zhang, Zhengwei Huang, Miaomiao Zheng, Ya Zhu, He Zhang, Weihong Song, Xi Li · 2022 · Ecotoxicology and Environmental Safety
  90. Search for factors contributing to resistance to the electroconvulsive seizure treatment model using adrenocorticotrophic hormone-treated mice
    Yurika Kobayashi, Eri Segi‐Nishida · 2019 · Pharmacology Biochemistry and Behavior
  91. Probiotic Bactolac alleviates depression-like behaviors by modulating BDNF, NLRP3 and MC4R levels, reducing neuroinflammation and promoting neural repair in rat model
    Musab Işık, Fadime Köse, Özcan Budak, Cansu Özbayer, Rümeysa KELEŞ, Sevda Aydın, Aleyna Ceren Küçük, Mehmet Arif Demirci, Songül Doğanay, Cahit Bağcı · 2025 · Pflügers Archiv - European Journal of Physiology
  92. Novel mechanisms underlying rapid-acting antidepressants: ketamine-like compounds, neurosteroid GABAkines, and psychedelics
    Sara Castanheira, Catarina Vale Gomes, Joana Bicker, Ana C. Fortuna · 2025 · Drug Discovery Today
  93. Neurometabolic effects of sweetened solution intake during adolescence related to depressive-like phenotype in rats
    Danusa Mar Arcego, Laura Ben Olivo, Rafael Oliveira de Moraes, Emily dos Santos Garcia, Ana Caroline Silva Silveira, Rachel Krolow, Natividade de Sá Couto Pereira, Carine Lampert, Ana Paula Toniazzo, F. Nicola et al. · 2020 · Nutrition
  94. The Immune System and Depression: From Epidemiological to Clinical Evidence
    Nina Vindegaard Sørensen, Michael E. Benros · 2022 · Current topics in behavioral neurosciences
  95. Sex difference in the non-linear relationship between ethylene oxide exposure and depressive symptoms: A cross-sectional study
    Shunli Jiang, Yongxin Wang, Mei Wang, Yaru Xu, Weitao Zhang, Xinyong Zhou, Xinpeng Niu, Mingjia Sun, Chen Feng, Liqun Wang et al. · 2023 · Journal of Affective Disorders
  96. Intranasal delivery of paroxetine: A preclinical study on pharmacokinetics, depressive-like behaviour, and neurochemical sex differences
    Soraia Silva, Joana Bicker, S. Fialho, Susana Cunha, Amílcar C. Falcão, Ana C. Fortuna · 2024 · Biochemical Pharmacology
  97. Hippocampal LASP1 ameliorates chronic stress-mediated behavioral responses in a mouse model of unpredictable chronic mild stress
    Yanhui Cui, Ao Fu, Xueqin Wang, Bo-Xuan Tu, Kangzhi Chen, Yi-Kai Wang, Qiong-Gui Hu, Lai-Fa Wang, Zhaolan Hu, Pinhua Pan et al. · 2020 · Neuropharmacology
  98. Lactation is not required for maintaining maternal care and active coping responses in chronically stressed postpartum rats: Interactions between nursing demand and chronic variable stress
    Joanna Medina, Rose M. De Guzman, Joanna L. Workman · 2021 · Hormones and Behavior
  99. Construction and Analysis of a Diagnostic Model Based on Differential Expression Genes in Patients With Major Depressive Disorder
    Qing Long, Rui Wang, Maoyang Feng, Xinling Zhao, Yilin Liu, Xiao Ma, Lei Yu, Shujun Li, Zeyi Guo, Yun Kai Zhu et al. · 2021 · Frontiers in Psychiatry
  100. Association Between Gut Microbiota and Depressive Symptoms: A Cross-Sectional Population-Based Study in South Korea
    Sun-Young Kim, Eunkyo Park, W. Lim, Soo In Kim, S. Jeon, Yoosoo Chang, S. Ryu, Hyung-Lae Kim, Han-Na Kim · 2022 · Psychosomatic Medicine