Epigenetic mechanisms of major depression: Targeting neuronal plasticity

Uchida, Shusaku, Yamagata, Hirotaka, Seki, Tomoe, Watanabe, Yoshifumi·2018·Psychiatry and Clinical Neurosciences
DOI 10.1111/pcn.12621

Cited by (181)

Items 101–181 of 181

  1. Genes associated with cellular senescence as diagnostic markers of major depressive disorder and their correlations with immune infiltration
    Juan Chen, Xin Xie, Min Lin, Hong Ryul Han, Tingting Wang, Qirong Lei, Rongfang He · 2024 · Frontiers in Psychiatry
  2. Exploring the shared genetic basis of major depressive disorder and frailty
    Wei Fu, Rong Xu, Peiyu Bian, Xu Li, Kaikai Yang, Xiaoming Wang · 2024 · Journal of Affective Disorders
  3. The role of senescence-related genes in major depressive disorder: insights from machine learning and single cell analysis
    Kun Lian, Wei Yang, Jing Ye, Yilan Chen, Lei Zhang, Xiufeng Xu · 2025 · BMC Psychiatry
  4. Different Frequency of Heschl’s Gyrus Duplication Patterns in Neuropsychiatric Disorders: An MRI Study in Bipolar and Major Depressive Disorders
    Tsutomu Takahashi, Daiki Sasabayashi, Murat Yücel, Sarah Whittle, Valentina Lorenzetti, Mark Walterfang, Michio Suzuki, Christos Pantelis, Gin Singh Malhi, Nicholas Brian Allen · 2022 · Frontiers in Human Neuroscience
  5. Intracellular Signaling Pathways Implicated in the Pathophysiology of Depression
    Gislaine Z. Réus, Jaqueline S. Generoso, Ana Lúcia S. Rodrigues, João Quevedo · 2019 · Elsevier eBooks
  6. Sex-Related Differences Linked to Depression Disorders and Chronic Inflammation Diseases in Nursing Shift Workers: An Expsloratory Multidimensional Literature Review
    A Calabrò, Elsa Vitale, Lorenzo Bardone · 2022 · Endocrine Metabolic & Immune Disorders - Drug Targets
  7. Depression: epigenetics and epitranscriptomic modifications
    Saradindu Banerjee, M S Shrilaxmi, Subhrojyoti Banerjee, B. G. Prajwal, Craig Smith, Santosh R. D’Mello, Somasish Ghosh Dastidar · 2025 · The World Journal of Biological Psychiatry
  8. Small non-coding RNA profiles in sperms from depressive-like mice induced by chronic unpredictable mild stimulations
    Jiaojiao Huang, Jinmei Zhang, Tianyi Wang, Xue Li, Hao Zhang, Junjie Wang, Yunliang Guo, Zhenhua Song, Qiu‐Yue Zhai · 2025 · Journal of Affective Disorders
  9. Genetic causal assessment between major depression and hypertension: A two-sample bidirectional Mendelian randomization study
    Yani Su, Ming Zhang, Peng Xu, Pengfei Wen, Ke Xu, Jiale Xie, Xianjie Wan, Lin Liu, Zhi Yang, Mingyi Yang · 2025 · Clinical and Experimental Hypertension
  10. Role of Dietary Polyphenols in NAD+-Dependent Deacetylase SIRT 1 in Stress-Induced Depression
    Nicole Less, Fúlvio Rieli Mendes, Giulio Maria Pasinetti · 2025 · Molecular Neurobiology
  11. Epigenome-Wide Association Study of Depressive Symptoms in Black Women in the InterGEN Study
    Brittany Taylor, Yihong Zhao, Nicole Beaulieu Perez, Stephanie Potts‐Thompson, Cindy A. Crusto, Ruth Masterson Creber, Jacquelyn Y. Taylor · 2024 · International Journal of Molecular Sciences
  12. The Potential of Biophilic Design and Nature to Improve Health, Creativity and Well-Being
    Isabelle A. K. Sjövall, Hugo J. Spiers · 2024 · Springer eBooks
  13. Peripheral blood miR-16-5p as a potential biomarker for distinguishing unmedicated bipolar disorder type II from major depressive disorder
    Ni, Longyan, Zhu, Yuanyuan, Lv, Lanlan, Zhang, Rongrong, Xie, Shiping, Zhang, Xiangrong · 2025 · Journal of Affective Disorders
  14. Neuroimaging and epigenetic analysis reveal novel epigenetic loci in major depressive disorder
    Hyun-Ho Yang, Kyu‐Man Han, Aram Kim, Youbin Kang, Woo‐Suk Tae, Mi-Ryung Han, Byung‐Joo Ham · 2024 · Psychological Medicine
  15. Aberrant MicroRNA-124 expression and methylation in the dorsolateral prefrontal cortex of depressed subjects
    Yu Funahashi, Shinichiro Ochi, Bhaskar Roy, Yogesh Dwivedi · 2025 · Journal of Psychiatric Research
  16. Midnight darkness and evening melatonin pre-treatment reverse night-light-induced neurobehavioural disruptions in a diurnal corvid
    Amaan Buniyaadi, Abhilash Prabhat, Sanjay Kumar Bhardwaj, Vinod Kumar · 2025 · Scientific Reports
  17. Different dosage regimens of zuranolone in the treatment of major depressive disorder: A meta-analysis of randomized controlled trials
    Jinrong Lian, Zhimin Lin, Xiang Li, Gang Chen, Depei Wu · 2024 · Journal of Affective Disorders
  18. Decoding Alzheimer's Disease With Depression: Molecular Insights and Therapeutic Target
    Zekun Li, Hongmin Guo, Yihao Ge, Xiaohan Li, Fang Dong, Feng Zhang · 2025 · Journal of Cellular and Molecular Medicine
  19. The potential of epigenetic methods to provide evidence of torture
    Paula Suárez-López · 2020 · Torture Journal
  20. 5hmC modification regulates R-loop accumulation in response to stress
    Xingyun Xu, Junjie Wang, Wenjuan Wang, Yutong Zhang, Bo Wan, Zhigang Miao, Xingshun Xu · 2023 · Frontiers in Psychiatry
  21. The Effects of Vitamin D on Movement and Cognitive Function in Senile Mice After Sevoflurane Anaesthesia
    Jialei Zhang, Xiaoling Zhang, Jun Li Zhao, Jie Wu · 2023 · Experimental Aging Research
  22. Gross anatomical features of the insular cortex in affective disorders
    Tsutomu Takahashi, Daiki Sasabayashi, Murat Yücel, Sarah Whittle, Michio Suzuki, Christos Pantelis, Gin Singh Malhi, Nicholas B. Allen · 2024 · Frontiers in Psychiatry
  23. The epidemiological burden of major depressive disorder in women of childbearing age and its relationship with the sociodemographic index: A systematic analysis based on the global burden of disease study from 1990 to 2021
    Bin Xu, Kaiyuan Li, Xiaowen Wang, Lei Wang, Yilong Man, Peng Liu · 2025 · Journal of Affective Disorders
  24. Cytosine Modifications and Distinct Functions of TET1 on Tumorigenesis
    Cuili Ma, Pengfei Ji, Nina Xie, Yujing Li · 2019 · IntechOpen eBooks
  25. Editorial: The role of epigenetics in neuropsychiatric disorders
    Margret Shirinian, Chong Chen, Shusaku Uchida, Nafisa M. Jadavji · 2022 · Frontiers in Molecular Neuroscience
  26. Association of Biomarkers with the Severity of Depression
    S.P. Agnihotri, Suresh Daripelly, Shirley Keerthana Cherla, Ajay Kumar Jopaka, Umashankar Molanguri · 2024 · Indian Journal of Psychological Medicine
  27. Hormonal Contraceptives and Depression: A Proteomic Analysis Using Neuronal Models
    Sam Thilmany, Andreas Thomas, Yvonne Reinders, Farhad Shakeri, Matthias Vogel, Albert Sickmann, Catharina Scholl, Mario Thevis · 2025 · PROTEOMICS - CLINICAL APPLICATIONS
  28. Unraveling the molecular pathways linking polystyrene exposure and depression
    Meesala Krishna Murthy · 2025 · Environmental Science and Pollution Research
  29. Cell Type‐Specific Loss of SIRT1 in Central Amygdala Leads to Depression‐Like Behaviors by Altering Neuronal Excitability in Mice
    Hui Huang, Xiao‐Bao Ding, Yuwen Lin, Wen‐Li Hu, Chen-Rui Zhou, Tian‐Qi Chen, Yue Zhou, Wei Dong, Chenghua Zhou, Yuqing Wu · 2026 · Acta Physiologica
  30. Addictive drug abuse and depression-a focus on epigenetics
    Wangwei Zhang, Mingyue Xu, Chong Wang, Hongyue Liang, Xu Zhu, Ying Pan, Feng Guo · 2026 · Communications Biology
  31. Sargassum pallidum reduces inflammation to exert antidepressant effect by regulating intestinal microbiome and ERK1/2/P38 signaling pathway
    Dan Su, Qianmin Li, Xin Lai, Yonggui Song, Huizhen Li, Zhifu Ai, Qi Zhang, Wenxiang Shao, Ming Hui Yang, Genhua Zhu · 2024 · Frontiers in Pharmacology
  32. Study on Mechanism of Xiaoyao Powder and Chaihu Shugan Powder for Treating Depression in “the Same Disease with Different Treatments” Based on Network Pharmacology and Bioinformatics
    文雯 刘 · 2021 · Traditional Chinese Medicine
  33. The influence of restless legs symptoms on musculoskeletal pain in depression
    Piritta Auvinen, Hannu Koponen, Hannu Kautiainen, Katariina Korniloff, Tiina Ahonen, Mauno J. Vanhala, Pekka T Mäntyselkä · 2020 · Scandinavian Journal of Pain
  34. Epigenetic regulations in neurological disorders
    Papiya Mondal, Subhajit Sarkar, Abhijit Das · 2023 · Elsevier eBooks
  35. Methylomic Alteration in Peripheral Blood Lymphocytes of Prodromal Stage and First-Episode Chinese Han Schizophrenia Patients
    Yi Liu, Bing Lang, Robert C. Smith, Guodong Wang, Jijun Wang, Liu Y, Hua Jin, Hailong Lyu, John M. Davis, Alessandro R. Guidotti et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  36. Association of major depressive disorder (MDD) with zinc levels and handgrip muscle strength in a sample of Colombian adults.
    Mª Natalia GARCÍA RESTREPO, Laura Victoria SÁNCHEZ DÍAZ, Cristian Giraldo Guzmán, Andrés TARRA ROMERO, Clara Helena González-Correa, Mª Eugenia AMEZQUITA MEDINA, Óscar Mauricio CASTAÑO RAMÍREZ · 2024 · Nutrición clínica y dietética hospitalaria/Nutrición clínica, dietética hospitalaria
  37. The interplay of prenatal stress and prenatal depression in Chinese couples: based on the actor-partner interdependence model
    Xiaoqing Liu, Yuting Dong, Jungu Zhou, Shiying Lin, Minghuan Liu, Hang Zeng, Xiaowan Zhou, Yang Song, Xiaoxu Xie, Qiuping Liao et al. · 2025 · Frontiers in Psychiatry
  38. Neurobiological mechanisms and recent advances in drug-based therapeutics in depression
    Hananeh Ahmadnia, Reza Abdollahzadeh, Hooman Hatami, Sara Masoumi, Seyed Mohammad Iman Moezzi, Kasra Shahsavari, Mahnaz Khanavi, Omid Yazarlu, Mohammad Tohidy Majd, Maede Hasanpour · 2025 · Neuroscience
  39. An observational feasibility study on the impact of green exposure on major depressive episode symptomatology and inflammatory biomarkers
    Gianna Pavarino, Claudio Brasso, Marina Boido, Anna Carluccio, Francesca Cirulli, Giulio Mengozzi, Roberta Schellino, Alessandro Vercelli, Paola Rocca · 2025 · Frontiers in Psychiatry
  40. Sirtuin 3, a mitochondrial metabolic enzyme, links the mitochondrial function to neurophysiology in depression
    Cong-Ya Chen, Yating Wang, Lingjie Liu, Yi Zhang · 2025 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  41. Relationship of immune-inflammatory pathway and stress-induced depression with neural regeneration
    Qingying Yu, Zhaoyu Chen, Jing Zhang, Yu Cao, Mengjia Sun, Shuyi Ye, Yike Huang, Junchi He, Liping Wang, Kejian Li et al. · 2025 · Neural Regeneration Research
  42. Mammalian torpor and depressive disorders: a review of evidence for a connection
    Douglas V. D’Agati, Donald C. D’Agati · 2026 · International Review of Psychiatry
  43. Epigenetics in depression
    Piotr Lech Czarny, Katarzyna I. Białek, Sylwia Ziółkowska, Monika Ewa Talarowska, Tomasz Śliwiński · 2021 · Elsevier eBooks
  44. Depression and Cancer: The Inflammatory Bridge
    Fernanda Leite, Ângela Maria Teixeira Leite · 2023 · Interdisciplinary cancer research
  45. Majör Depresif Bozuklukta Gen-Çevre Etkileşimi
    Beyza Şanal Güngör, Ali Güngör · 2024 · Humanistic Perspective
  46. Microbiome-Based Therapies for Mental Health Disorders
    Quratulain Maqsood, Mariam Aman, Nazim Hussain, Muhammad Saleem, Muhammada Mahnoor · 2024 · Springer eBooks
  47. Association of gene methylation status RLEP, LEP, FTO, BDNF and COMT with risk factors for eating disorders in Mexican university students
    R.G. Garfias-Guzmán, Margarita de Lorena Ramos‐García, Clementina Castro Hernández, Leonora Casas-Ávila, Ollin Celeste Martínez‐Ramírez · 2025 · Clinical Nutrition Open Science
  48. Neurobiologic correlates of depression: illustration of challenges in bench-to-bedside translation
    Bruce Edward Jones · 2020 · Elsevier eBooks
  49. Editorial: Brain Basis of Resilience and its Effect on Mood Disorders in the Aging
    Patricia Sampedro‐Piquero, Román D. Moreno‐Fernández · 2018 · Current Neuropharmacology
  50. Participação da metilação de DNA no desenvolvimento de alterações comportamentais e moleculares induzidas pelo estresse
    Amanda J. Sales · 2019
  51. The Functional Domain of Self-Other Regulation
    Nicolas Lorenzini, P. Fonagy, P. Luyten · 2021 · Depression and Personality Dysfunction
  52. Dysbiosis of Gut Microbiota and Activity of KYN Pathway as Potential Biomarkers in Patients With Major Depressive Disorder
    Ping Lin, Qingtian Li, Yun Shi, Dan Li, Xiaokui Guo, Ke Dong, Qing Chen, Xiaoyan Lou, Zhenhua Li, Ping Li et al. · 2021 · SSRN Electronic Journal
  53. Sintomas de depressão e/ou ansiedade em idosos: estudo de associação conjunta de genes candidatos
    Isabela Ferreira de Moraes · 2022
  54. VILAZODONE ENHANCES THE ENDURANCE CAPACITY AND IMPROVES THE BIOLOGICAL CHANGES IN TREADMILL TEST IN RATS
    Paula Alina Fotache · 2023 · The Medical-Surgical Journal
  55. DIDŽIOSIOS DEPRESIJOS SUKELIAMOS SUDĖTINGOS BŪKLĖS
    Kamilė Žalkauskaitė, Simona Varžaitė, Algirdas Musneckis · 2023 · Health Sciences
  56. Probiotic Bactolac Provides Antidepressant Effect by Increasing BDNF level and Reducing NLRP3 and MC4R Expression Levels, Neuron Damage, Glial Activity and Depression-Like Behaviors in Rats
    Musab Işık, Fadime Köse, Özcan Budak, Cansu Özbayer, Rümeysa KELEŞ, Sevda Aydın, Aleyna Ceren Küçük, Mehmet Arif Demirci, Songül Doğanay, Cahit Bağcı · 2024 · Research Square
  57. Unraveling the Genetic Interplay and Therapeutic Potentials between Major Depressive Disorder and Metabolic Syndrome: Multi-Ancestry and Multi-Trait Genome-Wide Association Analyses
    Yu Feng, Ningning Jia, Xiaochu Gu, Chenxu Xiao, Jing Shen · 2024 · Research Square
  58. La depresión como relacionalidad científico-cultural
    Laura Huerta Muñoz · 2023
  59. Epigenetic mechanisms of the maternal hyperhomocysteinemia influence on the placenta functional state and the offspring nervous system plasticity
    Alexander V. Arutjunyan, Yu. P. Milyutina, Anastasiia D. Shcherbitskaia, Gleb Olegovich Kerkeshko, Irina V. Zalozniaia · 2023 · Biochemistry (Moscow)
  60. ANALYSIS OF MODERN CONCEPTS OF NEURODEGENERATIVE PROPERTIES OF DEPRESSION
    Anna L. Yasenyavskaya, A. Tsibizova, М. А. Самотруева · 2023 · Molekulyarnaya Meditsina (Molecular medicine)
  61. Prevalência de ansiedade, depressão e estresse em profissionais da área da saúde e a relação com a experiência afetiva
    Ana Merzel Kernkraut · 2022
  62. Trauma exposure as a risk factor of major depressive disorder: A matched case-control study
    Wenjian Lai, Huimin Zhang, Yingchen Jiang, Xinyu Huang, Yuhua Liao, Jiejing Hao, Yifen Liu, Yan Chen, Wanxin Wang, Lan Guo et al. · 2025 · Journal of Psychiatric Research
  63. Chemoproteomics Sheds Light on Epigenetic Targets of [11C]Martinostat in the Human Brain
    Mary C. Catanese, Yvonne Eileen Klingl, Tonya M. Gilbert, Martin G. Strebl, Christina R. Hartigan, Monica Schenone, Jacob M. Hooker · 2025 · ACS Chemical Neuroscience
  64. Characterizing the Genetic Landscape of Major Depression through Multiple-trait and Cross-ancestry GWAS Meta-Analysis of 1,396,021 Individuals
    Yu Feng, Xiaolong Ji, Peng Huang, Sheng Yang · 2025 · Research Square
  65. PPARα deletion induces depressive-like behaviors by impairing neuronal synaptic plasticity and transmission
    Rengong Zhuo, Xiao-Ling Cheng, Luying Yang, Canmao Wang, Lichao Yang, Yanan Zhang, Ying Zeng, Ying Li · 2025 · Neuroscience
  66. Phthalate reduction as a mediator linking probiotic or yogurt consumption to reduced depressive Symptoms: Evidence from NHANES 2005–2018
    Ran Yao, Ximan Wang, Xiaoxia Dai, Jinbiao Zhang · 2025 · Food and Chemical Toxicology
  67. Bedeutung von Magnesium bei schweren Depressionen und deren Behandlung
    M Nechifor, Jürgen Vormann · 2025 · Springer eBooks
  68. Exploring Blood Glutamate as a Diagnostic Biomarker for Major Depressive Episodes in a Context of Major Depressive Disorder
    Khalil El Asmar, Tala El Ghoul, Romain Colle, Hugo Bottemanne, Rida Assaf, Séverine Martin, Séverine Trabado, Bruno Fève, Céline Verstuyft, Laurent Becquemont et al. · 2025 · Neuropsychobiology
  69. Inflamed and unrewarded: a narrative review exploring neuroinflammation and its impact on the brain’s reward mechanisms
    S.D. Sharma, Harsimar Kaur, Akshaya J. Kumar, Dhruv Nihal Gandhi, Vani Malhotra, Sahana Srinivasan, Puneeth Reddy · 2025 · International Journal of Research in Medical Sciences
  70. Nanotechnology-Enhanced MicroRNAs for Improved Diagnosis and Treatment of Major Depressive Disorder: A Comprehensive Review
    Abdulkareem Shareef, Hayder Naji Sameer, Ahmed Yaseen, Zainab H. Athab, Mohaned Adil, Omer Qutaiba B Allela · 2025 · Molecular Neurobiology
  71. Nomilin Regulates Depressive‐Like Behaviors in Mice via the Ventral Part of the Lateral Septum to Bed Nucleus of the Stria Terminalis Circuit
    Liang Chen, Boli Fu, Jiaxin Liu, Cun Wang, Weijun Huang, Danhua Yuan, Chen Qing, Yao Zhang, Hao Hong · 2025 · CNS Neuroscience & Therapeutics
  72. Additional file 1 of Association of circulating let-7b-5p with major depressive disorder: a nested case-control study
    Sanne Roumans, Kristina Sundquist, Ashfaque Ahmed Memon, Anna Hedelius, Jan Sundquist, Wang, Xiao · 2021 · Figshare
  73. Unraveling the genetic interplay and therapeutic potentials between major depressive disorder and metabolic syndrome: multi-ancestry and multi-trait genome-wide association analyses
    Yiheng Feng, Yihao Li, Hong Zhang, Huilin Xia, Yuan F. Lu, Hang Zhou, Peng Huang · 2026 · BMC Psychiatry
  74. Distinct prefrontal neuronal circuits determine repeated stress-induced behavioral styles in mice
    Shusaku Uchida · 2026 · Folia Pharmacologica Japonica
  75. Implication du métabolisme de la sérotonine dans les cancers du sein triple négatifs et perspectives cliniques
    Alice Marques Pinheiro · 2019 · theses.fr (ABES)
  76. Multi-omic molecular signatures from peripheral blood samples of patients with mood disorders
    Amazigh Mokhtari · 2022 · theses.fr (ABES)
  77. PACSIN2-mediated synaptic injury contributes to behavioral disorders caused by chronic stress
    Wang Chang-min, Ye Li, Yuhang Yi, Xiao Chen, Tian Lan, Hai-yan Lou, Wencheng Jian, Mei-jian Wang, Shu-yan Yu · 2026 · Acta Pharmacologica Sinica
  78. Genetic heterogeneity affects the risk of incident depression, comorbidity, and response to environment: A prospective trajectory study
    Chuyu Pan, Shiqiang Cheng, Xin Qi, Bolun Cheng, Jin Feng, Meijuan Kang, L L Liu, Xuena Yang, Yan Wen, Yumeng Jia et al. · 2026 · Psychological Medicine
  79. Neighborhood social vulnerability and depression prevalence in the United States
    Cong Gong, Weifang Liu, Peng Jiang, Yuting Wu, Meixin Zheng, Li Zhang, Ting Li, Anwen Wang, Yong Wu · 2026 · American Journal of Community Psychology
  80. Identification of AICD-associated transcriptomic markers in major depressive disorder
    Shengjie Xiong, Li Liao, Meng Chen, Rengde Peng, Quan Luo, Qing Gan, Weiping Yang · 2026 · Frontiers in Psychiatry
  81. Systematic review and meta-analysis of the antidepressant-like effects of ginsenosides in animal models: comparative behavioral profiles and exploratory dose-stratified analysis
    Yuhua Wu, Yao Jin, Lijiang Wang, Mengfei Dai, Zhujin Song · 2026 · Frontiers in Pharmacology