Double knockout pigs deficient in N ‐glycolylneuraminic acid and G alactose α‐1,3‐ G alactose reduce the humoral barrier to xenotransplantation
Lutz, Andrew J., Li, Ping, Estrada, Jose L., Sidner, Richard A., Chihara, Ray K., Downey, Susan M., Burlak, Christopher, Wang, Zheng‐Yu +6 more·2013·Xenotransplantation
Cited by (294)
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- Bortezomib, C1-Inhibitor and Plasma Exchange Do Not Prolong the Survival of Multi-Transgenic GalT-KO Pig Kidney Xenografts in BaboonsStéphanie Le Bas‐Bernardet, Xavier Tillou, Julien Branchereau, Nahzli Dilek, Nicolas Poirier, Mathias Chatelais, Béatrice L. Charreau, David Minault, Jérémy Hervouet, Karine Renaudin et al. · 2015 · American Journal of Transplantation
- Pig heart and lung xenotransplantation: Present statusRyan Chaban, David K. C. Cooper, Richard N. Pierson · 2022 · The Journal of Heart and Lung Transplantation
- Genetically modified animals: Options and issues for traceability and enforcementAntoon Lievens, Mauro Petrillo, Maddalena Querci, Alex Patak · 2015 · Trends in Food Science & Technology
- Cardiac Xenotransplantation: Progress in Preclinical Models and Prospects for Clinical TranslationAvneesh Kumar Singh, Corbin E. Goerlich, Aakash M. Shah, Tianshu Zhang, Ivan Tatarov, David Ayares, Keith A. Horvath, Muhammad M. Mohiuddin · 2022 · Transplant International
- Both Natural and Induced Anti-Sda Antibodies Play Important Roles in GTKO Pig-to-Rhesus Monkey XenotransplantationFeng, Hao, Li, Tao, Du, Jiaxiang, Xia, Qiangbing, Wang, Lu, Chen, Song, Zhu, Lan, Pan, Dengke, Wang, Yi, Chen, Gang · 2022 · Frontiers in Immunology
- First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes—Chapter 2b: genetically modified source pigsPeter J. Cowan, David Ayares, Eckhard Wolf, David K. C. Cooper · 2016 · Xenotransplantation
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- Cardiac xenotransplantation: a promising way to treat advanced heart failureSongren Shu, Jie Ren, Jiangping Song · 2020 · Heart Failure Reviews
- Human immune reactivity of GGTA1/CMAH/A3GALT2 triple knockout Yucatan miniature pigsJoohyun Shim, Nayoung Ko, Hyoung-Joo Kim, Yongjin Lee, Jeong-Woong Lee, Dong Il Jin, Hyunil Kim, Kimyung Choi · 2021 · Transgenic Research
- Characterization of Mono- and Bi-Transgenic Pig-Derived Epidermal Keratinocytes Expressing Human FUT2 and GLA Genes—In Vitro StudiesJerzy Wiater, Marcin Samiec, Kamil Wartalski, Z. Smorąg, Jacek Jura, Ryszard Słomski, Maria Skrzyszowska, Marek Romek · 2021 · International Journal of Molecular Sciences
- Advances in Innate Immunity to Overcome Immune Rejection during XenotransplantationTianyu Lu, Xue-Ling Xu, Xuguang Du, Jinhua Wei, Jianan Yu, Shoulong Deng, Chuan Qin · 2022 · Cells
- N-Glycolylneuraminic Acid (Neu5Gc) Null Large Animals by Targeting the CMP-Neu5Gc Hydroxylase (CMAH)Andrea Perota, Cesare Galli · 2019 · Frontiers in Immunology
- Silencing the porcine iGb3s gene does not affect Galα3Gal levels or measures of anticipated pig‐to‐human and pig‐to‐primate acute rejectionJames R. Butler, Nicholas James Skill, David Priestman, Frances M. Platt, Ping Li, Jose L. Estrada, Gregory R. Martens, Joseph M. Ladowski, Matthew F. Tector, Alfred Joseph Tector · 2016 · Xenotransplantation
- Development of a consensus protocol to quantify primate anti‐non‐ G al xenoreactive antibodies using pig aortic endothelial cellsAgnes M. Azimzadeh, Guerard W. Byrne, Mohamed B. Ezzelarab, Emily E. Welty, Gheorghe Braileanu, Xiangfei Cheng, Simon Christopher Robson, Christopher G.A. McGregor, David K. C. Cooper, Richard N. Pierson · 2014 · Xenotransplantation
- Generation of CMAHKO/GTKO/shTNFRI-Fc/HO-1 quadruple gene modified pigsGeon A Kim, Eun Mi Lee, Jun‐Xue Jin, Sanghoon Lee, Anukul Taweechaipaisankul, Jong‐Ik Hwang, Zahid Alam, Curie Ahn, Byeong Chun Lee · 2017 · Transgenic Research
- Level of acceptance of solid organ xenotransplantation among personnel in S panish, M exican, and C uban hospitalsAntonio Ríos, Laura Martínez-Alarcón, Ana Isabel López‐Navas, Marco Antonio Ayala‐García, Ma José Sebastián, Anselmo Abdo Cuza, Ector Jaime Ramírez, Gerardo Muñoz, Gerardo Palacios, Juliette Suárez‐López et al. · 2013 · Xenotransplantation
- Use of genetically-engineered pig donors in islet transplantation.R. Bottino, M. Trucco · 2015 · World journal of transplantation
- Immunological Challenges and Therapies in XenotransplantationMarta Vadori, Emanuele Cozzi · 2014 · Cold Spring Harbor Perspectives in Medicine
- Lung xenotransplantationChris T. Laird, Lars Burdorf, Richard N. Pierson · 2016 · Current Opinion in Organ Transplantation
- The role of sialic acids in the immune recognition of xenograftsBeth M. French, Selin Sendil, Richard N. Pierson, Agnes M. Azimzadeh · 2017 · Xenotransplantation
- Antibody reactivity with new antigens revealed in multi‐transgenic triple knockout pigs may cause early loss of pig kidneys in baboonsYuichi Ariyoshi, Kazuhiro Takeuchi, Thomas Pomposelli, Dilrukshi K. Ekanayake‐Alper, Akira Shimizu, Lennan Boyd, Ermance Estime, Mayu Ohta, Arsenoi Asfour, John Scott Arn et al. · 2020 · Xenotransplantation
- Nematic Fibrin Fibers Enabling Vascularized Thrombus Implants Facilitate Scarless Cutaneous Wound HealingSu Hyun Jung, Bong Hwan Jang, Seyong Kwon, Sung Jin Park, Tae‐Eun Park, Joo Hee Kang · 2023 · Advanced Materials
- Immunogenicity of Renal Microvascular Endothelial Cells From Genetically Modified PigsZheng‐Yu Wang, Ping Li, James R. Butler, Ross L. Blankenship, Susan M. Downey, Jessica B. Montgomery, Shunji Nagai, Jose L. Estrada, Matthew F. Tector, Alfred Joseph Tector · 2016 · Transplantation
- The case for xenotransplantationDavid K.C. Cooper · 2015 · Clinical Transplantation
- HLA-G1+ Expression in GGTA1KO Pigs Suppresses Human and Monkey Anti-Pig T, B and NK Cell ResponsesJoseph Sushil Rao, Nora Hosny, Ramesh Kumbha, Raza Ali Naqvi, Amar Ranjan Singh, Zachary A. Swanson, Heather Levy, Anders W. Matson, Magie Steinhoff, Nicole Forneris et al. · 2021 · Frontiers in Immunology
- Pretransplant Screening for Prevention of Hyperacute Graft Loss in Pig-to-primate Kidney XenotransplantationYu Hisadome, Daniel L. Eisenson, Michelle R. Santillan, Hayato Iwase, Kazuhiko Yamada · 2024 · Transplantation
- Modified glycan models of pig-to-human xenotransplantation do not enhance the human-anti-pig T cell responseJames R. Butler, Zheng‐Yu Wang, Gregory R. Martens, Joseph M. Ladowski, Ping Li, Matthew F. Tector, Alfred Joseph Tector · 2016 · Transplant Immunology
- Pig islet xenotransplantationM. Dhanasekaran, Johnathan J George, G. Loganathan, S. Narayanan, M. Hughes, S. Williams, A. Balamurugan · 2017 · Current Opinion in Organ Transplantation
- In vitro characterization of neonatal, juvenile, and adult porcine islet oxygen demand, β‐cell function, and transcriptomesKate E. Smith, William G. Purvis, Melissa Ann Davis, Catherine G. Min, Amanda M. Cooksey, Craig S. Weber, Jana Jandová, Nicholas D. Price, Diana S. Molano, James Brett Stanton et al. · 2018 · Xenotransplantation
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- CRISPR editing in biological and biomedical investigationJiaojiao Huang, Yanfang Wang, Jianguo Zhao · 2017 · Journal of Cellular Physiology
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- A desirable transgenic strategy using GGTA1 endogenous promoter-mediated knock-in for xenotransplantation modelNayoung Ko, Joohyun Shim, Hyoung-Joo Kim, Yongjin Lee, Jae‐kyung Park, Kyungmin Kwak, Jeong-Woong Lee, Dong Il Jin, Hyunil Kim, Kimyung Choi · 2022 · Scientific Reports
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- Genetic strategies to bring islet xenotransplantation to the clinicW. Hawthorne, A. Lew, H. Thomas · 2016 · Current Opinion in Organ Transplantation
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- Immune Modulation in XenotransplantationMagdalena Hryhorowicz, Joanna Zeyland, Ryszard Słomski, Daniel Lipiński · 2014 · Archivum Immunologiae et Therapiae Experimentalis
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- Assembling multiple xenoprotective transgenes in pigsKonrad Fischer, Alexander Kind, Angelika Schnieke · 2018 · Xenotransplantation
- Complement-targeted therapies in kidney transplantation—insights from preclinical studiesImran John Anwar, Isabel F. DeLaura, Joseph M. Ladowski, Qimeng Gao, Stuart J. Knechtle, Jean Kwun · 2022 · Frontiers in Immunology
- Characterization of the cellular infiltrate in bioprosthetic heart valves explanted from patients with structural valve deteriorationRizwan A. Manji, Hidetaka Hara, David K. C. Cooper · 2015 · Xenotransplantation
- Islet xenotransplantation from genetically engineered pigsSantosh Nagaraju, Rita Bottino, Martin N. Wijkstrom, Hidetaka Hara, Massimo Trucco, David K. C. Cooper · 2013 · Current Opinion in Organ Transplantation
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- American Society of Transplant Surgeons-American Society of Transplantation report of FDA meeting on regulatory expectations for xenotransplantation productsAndrew B. Adams, Linda C. Cendales, David K.C. Cooper, Emanuele Cozzi, John S. Gill, Eric K. Judd, Eliezer Katz, Allan D. Kirk, Jay Alan Fishman, Peter Philip Reese et al. · 2023 · American Journal of Transplantation
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- Lung xenotransplantation: recent progress and current statusDonald G. Harris, Kevin J. Quinn, Siamak Dahi, Lars Burdorf, Agnes M. Azimzadeh, Richard N. Pierson · 2014 · Xenotransplantation
- Current Techniques of Gene Editing in Pigs for XenotransplantationCesare Galli · 2025 · Transplant International
- Introduction: The Present Status of Xenotransplantation ResearchDavid K.C. Cooper · 2020 · Methods in molecular biology
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- Gene-editing technology, from macromolecule therapeutics to organ transplantation: Applications, limitations, and prospective usesGamaleldin I. Harisa, Tarek M. Faris, Abdelrahman Y. Sherif, Riyad F. Alzhrani, Saleh A. Alanazi, Neveen A. Kohaf, Fars Kaed Alanazi · 2023 · International Journal of Biological Macromolecules
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