NMDA receptor‐dependent long‐term potentiation in mouse hippocampal interneurons shows a unique dependence on Ca 2+ /calmodulin‐dependent kinases

Lamsa, Karri; Irvine, Elaine E.; Giese, K. Peter; Kullmann, Dimitri M.

doi:10.1113/jphysiol.2007.137380

NMDA receptor‐dependent long‐term potentiation in mouse hippocampal interneurons shows a unique dependence on Ca 2+ /calmodulin‐dependent kinases

Long‐term potentiation (LTP) of excitatory synaptic transmission plays a major role in memory encoding in the cerebral cortex. It can be elicited at many synapses on principal cells, where it depends on Ca 2+ influx through postsynaptic N ‐methyl‐ d ‐aspartic acid (NMDA) receptors. Ca 2+ influx t…