Mechanics of Motor Proteins and the Cytoskeleton
Abstract
Preface - Introduction - PART I: PHYSICAL PRINCIPLES - Mechanical Forces - Mass, Stiffness, and Damping of Proteins - Thermal Forces and Diffusion - Chemical Forces - Polymer Mechanics - PART II: CYTOSKELETON - Structures of Cytoskeletal Filaments - Mechanics of the Cytoskeleton - Polymerization of Cytoskeletal Filaments - Force Generation by Cytoskeletal Filaments - Active Polymerization - PART III: MOTOR PROTEINS - Structures of Motor Proteins - Speeds of Motors - ATP Hydrolysis - Steps and Forces - Motility Models: From Crossbridges to Motion - Afterword - Appendix - Bibliography - Index
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The calculation of low duty ratio relies only on the difference in time to wait for ATP binding between the process of ATP hydrolysis and that of mechanical force generation.
“The calculation relies only on the difference in time to wait for ATP binding between the process of ATP hydrolysis and that of mechanical force generation (37).”
From Diffusion and Directed Movement (2008) · cites this paper as [37]
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Cited by 2,909
- Authors
- Howard, & Clark
- Affiliations
- University of Washington (US)
- Duke University (US)
- ORCID
- Howard,, J
- Venue
- Applied Mechanics Reviews
- Publisher
- ASME International
- Published
- 2002-03-01
- Volume
- 55
- Issue
- 2
- Pages
- B39-B39
- ISSN
- 0003-6900 (ISSN-L)
- 2379-0407
- OpenAlex
- W2151274733
- Cited by
- 2,909
- References
- 0
- Citations by year
- 2026: 10 · 2025: 30 · 2024: 54 · 2023: 62 · 2022: 76 · 2021: 81 · 2020: 105 · 2019: 116 · 2018: 88 · 2017: 138 · 2016: 117 · 2015: 126 · 2014: 146 · 2013: 125 · 2012: 170
- FWCI
- 50.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Applied Mechanics Reviews (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Microtubule and mitosis dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
- Keywords
- motor proteins, cytoskeleton, mechanical forces, protein mechanics, thermal force, diffusion, polymer mechanics, cytoskeletal filaments, filament polymerization, ATP hydrolysis, cross-bridges
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