Cited by 2,909Microtubule and mitosis dynamicsCellular Mechanics and InteractionsProtein Structure and Dynamics

Mechanics of Motor Proteins and the Cytoskeleton

Howard,, J, Clark,, RL·2002·Applied Mechanics Reviews

Abstract

Preface - Introduction - PART I: PHYSICAL PRINCIPLES - Mechanical Forces - Mass, Stiffness, and Damping of Proteins - Thermal Forces and Diffusion - Chemical Forces - Polymer Mechanics - PART II: CYTOSKELETON - Structures of Cytoskeletal Filaments - Mechanics of the Cytoskeleton - Polymerization of Cytoskeletal Filaments - Force Generation by Cytoskeletal Filaments - Active Polymerization - PART III: MOTOR PROTEINS - Structures of Motor Proteins - Speeds of Motors - ATP Hydrolysis - Steps and Forces - Motility Models: From Crossbridges to Motion - Afterword - Appendix - Bibliography - Index

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Crossref · 10.1115/1.1451234

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  • The calculation of low duty ratio relies only on the difference in time to wait for ATP binding between the process of ATP hydrolysis and that of mechanical force generation.

    “The calculation relies only on the difference in time to wait for ATP binding between the process of ATP hydrolysis and that of mechanical force generation (37).”

    From Diffusion and Directed Movement (2008) · cites this paper as [37]

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Cited by 2,909

Authors
Howard, & Clark
Affiliations
  • University of Washington (US)
  • Duke University (US)
Venue
Applied Mechanics Reviews
Published
2002-03-01
Volume
55
Issue
2
Pages
B39-B39
ISSN
  • 0003-6900 (ISSN-L)
  • 2379-0407
OpenAlex
W2151274733
Cited by
2,909
References
0
Citations by year
2026: 10 · 2025: 30 · 2024: 54 · 2023: 62 · 2022: 76 · 2021: 81 · 2020: 105 · 2019: 116 · 2018: 88 · 2017: 138 · 2016: 117 · 2015: 126 · 2014: 146 · 2013: 125 · 2012: 170
FWCI
50.22
Type
journal article
Language
en
Open access
closed
Locations
Applied Mechanics Reviews (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Microtubule and mitosis dynamics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
Keywords
motor proteins, cytoskeleton, mechanical forces, protein mechanics, thermal force, diffusion, polymer mechanics, cytoskeletal filaments, filament polymerization, ATP hydrolysis, cross-bridges

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