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MRI‐guided noninvasive ultrasound surgery
Abstract
In this study, the feasibility of using magnetic resonance imaging (MRI) to detect tissue necrosis induced by focussed ultrasound beams was investigated. It was shown that lesions produced in dog's thigh muscle in vivo were clearly visible in T2‐weighted images and that the lesion dimensions measured from the images correlated with the postmortem measurements of the visible tissue damage. It was also shown that the sonications can be done in the magnet and that the lesions are visible immediately after the sonications with increasing image contrast as a function of time. These results showed that MRI can be used to direct and monitor on‐line noninvasive ultrasound surgery. This may have a major impact in future patient treatments.
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Citations
Cited by
Therapeutic applications of ultrasound
ter Haar, G. (2007) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2006.07.005 · Cited by 721
Molecular diffusion, tissue microdynamics and microstructure
Bihan, D. L. (1995) · NMR in Biomedicine · doi:10.1002/nbm.1940080711 · Cited by 497
Izadifar, Z., Izadifar, Z., Chapman, D., & Babyn, P. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9020460 · Cited by 457
Noninvasive estimation of tissue temperature response to heating fields using diagnostic ultrasound
Seip, R., & Ebbini, E. S. (1995) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.398644 · Cited by 384
MRI-Guided Focused Ultrasound Surgery
Jolesz, F. A. (2009) · Annual Review of Medicine · doi:10.1146/annurev.med.60.041707.170303 · Cited by 377
Metadata
- Authors
- Hynynen, K., Darkazanli, A., Unger, E., & Schenck, J. F.
- Venue
- Medical Physics
- Publisher
- Wiley
- Published
- 1993-01
- Volume
- 20
- Issue
- 1
- Pages
- 107-115
- ISSN
- 0094-2405 (ISSN-L)
- 2473-4209
- OpenAlex
- W2023981146
- Cited by
- 327
- References
- 0
- FWCI
- 12.95
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hynynen, K., Darkazanli, A., Unger, E., & Schenck, J. F. (1993). MRI‐guided noninvasive ultrasound surgery. Medical Physics. https://doi.org/10.1118/1.597093
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.