Characterization of Risk Quantification Differences Using Female Athlete Triad Cumulative Risk Assessment and Relative Energy Deficiency in Sport Clinical Assessment Tool
Abstract
This study's objective was to identify differences in risk for low energy availability and athletic clearance level by comparing scores on Female Athlete Triad Cumulative Risk Assessment (Triad CRA) and Relative Energy Deficiency in Sport Clinical Assessment Tool (RED-S CAT). A total of 1,000 female athletes aged 15-30 years participating in ≥4 hr of physical activity/week for the previous ≥6 months completed an extensive survey assessing health, athletic history, family disease history, and specific Triad/RED-S risk factors. Retrospective chart review ascertained laboratory and bone mineral density measures. Triad CRA and RED-S CAT were used to assign each athlete's risk level (low, moderate, and high), and case-by-case comparison measured the level of agreement between the tools. We hypothesized that the tools would generally agree on low-risk athletes and that the tools would be less aligned in the specific elevated risk level (moderate or high). Most of the sample was assigned moderate or high risk for Triad CRA and RED-S CAT (Triad: 54.7% moderate and 7.9% high; RED-S: 63.2% moderate and 33.0% high). The tools agreed on risk for 55.5% of athletes. Agreement increased to 64.3% when only athletes with bone mineral density measurements were considered. In conclusion, Triad CRA and RED-S CAT provide consensus on the majority of athletes at elevated (moderate or high) risk for low energy availability, but have less agreement on the specific risk level assigned.
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Current findings show a strong correlation between the Female Athlete Triad and negative bone health outcomes, such as increased bone stress injuries and decreased bone mineral density.
“current findings show a strong correlation between Triad and negative bone health outcomes, such as increased bone stress injuries and decreased BMD [6,7,9,11,14,15,16,17,18].”
From Considerations of Low Carbohydrate Availability (LCA) to Relative Energy Deficiency in Sport (RED-S) in Female Endurance Athletes: A Narrative Review (2023) · cites this paper as [17]
Estrogen impairs gluconeogenesis.
“Estrogen, a sex hormone that regulates the female reproductive system, impairs gluconeogenesis [17].”
From Considerations of Low Carbohydrate Availability (LCA) to Relative Energy Deficiency in Sport (RED-S) in Female Endurance Athletes: A Narrative Review (2023) · cites this paper as [17]
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References 20 · Cited by 26
- Authors
- Holtzman, B., Tenforde, A. S., Parziale, A. L., & Ackerman, K. E.
- Affiliations
- Boston Children's Hospital (US)
- Harvard University (US)
- Venue
- International Journal of Sport Nutrition and Exercise Metabolism
- Publisher
- Human Kinetics
- Published
- 2019-11-01
- Volume
- 29
- Issue
- 6
- Pages
- 569-575
- ISSN
- 1526-484X (ISSN-L)
- 1543-2742
- OpenAlex
- W2943322244
- Cited by
- 26
- References
- 20
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 1 · 2023: 5 · 2021: 7 · 2020: 7 · 2019: 1
- FWCI
- 4.38
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Sport Nutrition and Exercise Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Physical Sciences › Engineering › Biomedical Engineering › Lower Extremity Biomechanics and Pathologies
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Keywords
- female athlete triad, relative energy deficiency in sport, low energy availability, risk assessment tools, bone mineral density, female athletes
- MeSH terms
- Relative Energy Deficiency in Sport, Adolescent, Adult, Female, Humans, Surveys and Questionnaires, Retrospective Studies, Risk Assessment, Young Adult
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