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Impact of Curcumin-Induced Changes in P-Glycoprotein and CYP3A Expression on the Pharmacokinetics of Peroral Celiprolol and Midazolam in Rats
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“Most recently, in vivo studies of curcuminoids given to rats showed elevated plasma levels of co-administered midazolam, a marker substrate for CYP3A metabolism (Zhang et al., 2007).”
From Curcuminoids Inhibit Multiple Human Cytochromes P450, UDP-Glucuronosyltransferase, and Sulfotransferase Enzymes, whereas Piperine Is a Relatively Selective CYP3A4 Inhibitor (2008) · cites this paper as Zhang et al., 2007
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Cites
The effect of garlic supplements on the pharmacokinetics of saquinavir
Piscitelli, S. C., Burstein, A. H., Welden, N., Gallicano, K. D., & Falloon, J. (2002) · Clinical Infectious Diseases · doi:10.1086/324351 · Cited by 431
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Cited by
Volak, L. P., Ghirmai, S., Cashman, J. R., & Court, M. H. (2008) · Drug Metabolism and Disposition · doi:10.1124/dmd.108.020552 · Cited by 214
Metadata
- Authors
- Zhang, W., Tan, T. M. C., & Lim, L.-Y.
- Venue
- Drug Metabolism and Disposition
- Publisher
- Elsevier BV
- Published
- 2007-01
- Volume
- 35
- Issue
- 1
- Pages
- 110-115
- ISSN
- 0090-9556
- Cited by
- 121
- References
- 1
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
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- Zhang, W., Tan, T. M. C., & Lim, L.-Y. (2007). Impact of Curcumin-Induced Changes in P-Glycoprotein and CYP3A Expression on the Pharmacokinetics of Peroral Celiprolol and Midazolam in Rats. Drug Metabolism and Disposition. https://doi.org/10.1124/dmd.106.011072
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.