Sazetidine-A Is a Potent and Selective Agonist at Native and Recombinant α4β2 Nicotinic Acetylcholine Receptors

Cited by (120)

Items 101–120 of 120

1. [18F]5-(6-Fluorohexyn-1-yl)-3-[2(S)-2-azetidinylmethoxy]pyridine
   Kam Leung · 2010 · Europe PMC (PubMed Central)
2. Experimental Studies of Subdiaphragmatic Vagotomy and Nicotine for Reducing Body Weight
   Ghazaul Dezfuli · 2014 · DigitalGeorgetown (Georgetown University Library)
3. Development of Antidepressant Drugs Through Targeting α4β2-Nicotinic Acetylcholine Receptors
   Hankun Zhang, Hendra Gunosewoyo, Yan Fan, Jie Tang, Li-Fang Yu · 2016 · Neuromethods
4. TOWARDS AN UNDERSTANDING OF PHARMACOLOGICALLY INDUCED INTRACELLULAR CHANGES IN NICOTINIC ACETYLCHOLINE RECEPTORS
   Ashley M. Fox-Loe · 2016 · UKnowledge (University of Kentucky)
5. Nicotinic Signalling and Neurosteroid Modulation in Principal Neurons of the Hippocampal Formation and Prefrontal Cortex
   Beryl Y.T. Chung · 2018 · The Atrium (University of Guelph)
6. Neuronal Nicotinic Acetylcholine Receptors
   John A. Dani, Robin A. J. Lester, Roger L. Papke · 2021 · Wiley eBooks
7. Allosteric Control of Super-Agonism in a Ligand-Gated Ion Channel
   Franco Viscarra, Teresa Minguez, Isabel Bermúdez, Philip Charles Biggin · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
8. Pyridine- and quinoline-based piperazine nitriles: Potent and selective 5-HT3 receptor agonists and efficacious desensitizers
   Anders A. Jensen · 2026 · Biomedicine & Pharmacotherapy
9. The CAGE Framework (Calcium-Gated Excitability): From Single Neurotransmitters to Calcium States in the Tumor Microenvironment
   Lena M. Rudy, Michał M. Godlewski · 2026 · International Journal of Molecular Sciences
10. BindingDB Entry 50041858: Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) asa4ß2-nicotinic acetylcholine receptor-selective partial agonists.
    BindingDB · 2013 · UC San Diego
11. BindingDB Entry 50033996: Discovery of isoxazole analogues of sazetidine-A as selectivea4ß2-nicotinic acetylcholine receptor partial agonists for the treatment of depression.
    BindingDB · 2012 · UC San Diego
12. BindingDB Entry 50042577: Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selectivea4ß2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats.
    BindingDB · 2013 · UC San Diego
13. BindingDB Entry 50043799: Scaffold ranking and positional scanning utilized in the discovery of nAChR-selective compounds suitable for optimization studies.
    BindingDB · 2014 · UC San Diego
14. BindingDB Entry 50045100: Recent developments in novel antidepressants targetinga4ß2-nicotinic acetylcholine receptors.
    BindingDB · 2016 · UC San Diego
15. BindingDB Entry 50046454: Chemistry and Pharmacology of a Series of Unichiral Analogues of 2-(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3-Pyridyl Ether Designed asa4ß2-Nicotinic Acetylcholine Receptor Agonists.
    BindingDB · 2016 · UC San Diego
16. BindingDB Entry 50047074: New quinoline derivatives as nicotinic receptor modulators.
    BindingDB · 2017 · UC San Diego
17. BindingDB Entry 50039698: Chemistry and behavioral studies identify chiral cyclopropanes as selectivea4ß2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile.
    BindingDB · 2013 · UC San Diego
18. BindingDB Entry 50015555: Novel methyllycaconitine analogues selective for the α4β2 over α7 nicotinic acetylcholine receptors.
    BindingDB · 2023 · UC San Diego
19. BindingDB Entry 50023329: The Heterogeneous Kinetic Origins of the Binding Properties of Orthosteric Ligands at Heteromeric Nicotinic Acetylcholine Receptors.
    BindingDB · 2026 · UC San Diego
20. Regulation of Neuronal Nicotinic Receptor Expression by Novel Ligands and Mechanisms
    G. Patrick Hussmann · 2012 · DigitalGeorgetown (Georgetown University Library)