Glutamate Receptor Ion Channels: Structure, Regulation, and Function

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Items 201–300 of 1,014

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    Straub, Christoph, Hunt, David L, Yamasaki, Miwako, Kim, Kwang S, Watanabe, Masahiko, Castillo, Pablo E, Tomita, Susumu · 2011 · Nature Neuroscience
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  8. Comprehensive RNA-Seq Expression Analysis of Sensory Ganglia with a Focus on Ion Channels and GPCRs in Trigeminal Ganglia
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  9. GLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonists
    Joseph R. Moskal, Ronald M. Burch, Jeffrey S. Burgdorf, Roger A. Kroes, Patric K. Stanton, John F. Disterhoft, J. David Leander · 2013 · Expert Opinion on Investigational Drugs
  10. Molecular Pathways: Dysregulated Glutamatergic Signaling Pathways in Cancer
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  11. AMPA receptor inhibition by synaptically released zinc
    Bopanna I. Kalappa, Charles T. Anderson, Jacob M. Goldberg, Stephen J. Lippard, Thanos Tzounopoulos · 2015 · Proceedings of the National Academy of Sciences
  12. Modulation of extrasynaptic NMDA receptors by synaptic and tonic zinc
    Charles T. Anderson, Robert J. Radford, Melissa L. Zastrow, Daniel Yang Zhang, Ulf‐Peter Apfel, Stephen J. Lippard, Thanos Tzounopoulos · 2015 · Proceedings of the National Academy of Sciences
  13. De novo mutations and rare variants occurring in NMDA receptors
    Wenshu XiangWei, Yuwu Jiang, Hongjie Yuan · 2017 · Current Opinion in Physiology
  14. Expression of Cocaine-Evoked Synaptic Plasticity by GluN3A-Containing NMDA Receptors
    Tifei Yuan, Manuel Mameli, Eoin C. O’Connor, Partha Narayan Dey, Chiara Verpelli, Carlo Sala, Isabel Pérez‐Otaño, Christian Lüscher, Camilla Bellone · 2013 · Neuron
  15. Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury
    Enmanuel J. Perez, Stephen A. Tapanes, Zachary B. Loris, Darrick T. Balu, Thomas J. Sick, Joseph T. Coyle, Daniel J. Liebl · 2017 · Journal of Clinical Investigation
  16. Two glutamate- and pH-regulated Ca 2+ channels are required for systemic wound signaling in Arabidopsis
    Qiaolin Shao, Qifei Gao, Dhondup Lhamo, Hongsheng Zhang, Sheng Luan · 2020 · Science Signaling
  17. Neuroinflammation in Alzheimer’s disease: insights from peripheral immune cells
    Qiang Zhang, Guanhu Yang, Yuan Luo, Lai Jiang, Hao Chi, Gang Tian · 2024 · Immunity & Ageing
  18. X-ray structures of AMPA receptor–cone snail toxin complexes illuminate activation mechanism
    Lei Chen, Katharina L. Dürr, Eric Gouaux · 2014 · Science
  19. Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology
    Kevin K. Ogden, Wenjuan Chen, Sharon A. Swanger, Miranda J. McDaniel, Linlin Z. Fan, Chun Hu, Anel Tankovic, Hirofumi Kusumoto, Gabrielle J. Kosobucki, Anthony J. Schulien et al. · 2017 · PLoS Genetics
  20. Synaptic GluN2A-Containing NMDA Receptors: From Physiology to Pathological Synaptic Plasticity
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  21. Beyond the Random Coil: Stochastic Conformational Switching in Intrinsically Disordered Proteins
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  22. ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d -serine and neurodevelopment
    Eitan Kaplan, Salman Zubedat, Inna S. Radzishevsky, Alec C. Valenta, Ohad Rechnitz, Hagit Sason, Clara Sajrawi, Oded Bodner, Kohtarou Konno, Kayoko Esaki et al. · 2018 · Proceedings of the National Academy of Sciences
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  24. Glutamate Receptor Homologs in Plants: Functions and Evolutionary Origins
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  25. NMDA Receptor Function During Senescence: Implication on Cognitive Performance
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  26. Structure and organization of heteromeric AMPA-type glutamate receptors
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    Zhou, Xinyi, Xiao, Qian, Xie, Li, Yang, Fan, Wang, Liping, Tu, Jie · 2019 · Frontiers in Molecular Neuroscience
  30. The Concise Guide to PHARMACOLOGY 2013/14: Ligand‐Gated Ion Channels
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  31. NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer's Therapy
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    Anna V. Leopold, Daria M. Shcherbakova, Vladislav V. Verkhusha · 2019 · Frontiers in Cellular Neuroscience
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  34. Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
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  35. Subunit‐selective N‐terminal domain associations organize the formation of AMPA receptor heteromers
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  36. Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain
    Watson, Jake F, Ho, Hinze, Greger, Ingo H · 2017 · eLife
  37. Structure and Assembly Mechanism for Heteromeric Kainate Receptors
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  38. The NMDA receptor complex: a multifunctional machine at the glutamatergic synapse
    Xuelai Fan, Wu Yang Jin, Yu Tian Wang · 2014 · Frontiers in Cellular Neuroscience
  39. miR-191 and miR-135 are required for long-lasting spine remodelling associated with synaptic long-term depression
    Zhonghua Hu, Danni Yu, Qin-hua Gu, Yanqin Yang, Kang Tu, Jun Zhu, Zheng Li · 2014 · Nature Communications
  40. Structural Basis of Functional Transitions in Mammalian NMDA Receptors
    Tsung‐Han Chou, Nami Tajima, Annabel Romero Hernandez, Hiro Furukawa · 2020 · Cell
  41. Recent insights into the mode of action of memantine and ketamine
    Jon W. Johnson, Nathan G. Glasgow, Nadezhda V. Povysheva · 2014 · Current Opinion in Pharmacology
  42. Cholinergic connectivity: it's implications for psychiatric disorders
    Elizabeth Scarr, Andrew Stuart Gibbons, Jaclyn H Neo, Madhara Udawela, Brian Dean · 2013 · Frontiers in Cellular Neuroscience
  43. GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity
    Perszyk, Riley E., DiRaddo, John O., Strong, Katie L., Low, Chian-Ming, Ogden, Kevin K., Khatri, Alpa, Vargish, Geoffrey A., Pelkey, Kenneth A., Tricoire, Ludovic, Liotta, Dennis C. et al. · 2016 · Molecular Pharmacology
  44. Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cells
    Marzieh Zonouzi, Massimiliano Renzi, Mark Farrant, Stuart Graham Cull-Candy · 2011 · Nature Neuroscience
  45. Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry
    Jesse E. Hanson, Hongjie Yuan, Riley E. Perszyk, Tue G. Banke, Hao Xing, Ming‐Chi Tsai, Frank S. Menniti, Stephen F. Traynelis · 2023 · Neuropsychopharmacology
  46. NMDA Receptor Activation-Dependent Antidepressant-Relevant Behavioral and Synaptic Actions of Ketamine
    Zanos, Panos, Brown, Kyle A., Georgiou, Polymnia, Yuan, Peixiong, Zarate, Carlos A., Thompson, Scott M., Gould, Todd D. · 2023 · The Journal of Neuroscience
  47. Targeting of NMDA receptors in new treatments for schizophrenia
    Kenji Hashimoto · 2014 · Expert Opinion on Therapeutic Targets
  48. Architecture of fully occupied GluA2 AMPA receptor–TARP complex elucidated by cryo-EM
    Yan Zhao, Shanshuang Chen, Craig Yoshioka, Isabelle Baconguis, Eric Gouaux · 2016 · Nature
  49. AMPA receptors and their minions: auxiliary proteins in AMPA receptor trafficking
    Diane Bissen, Franziska Foss, Amparo Acker‐Palmer · 2019 · Cellular and Molecular Life Sciences
  50. Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities
    Xiaoying Jiang, Kaiyu Wu, Renren Bai, Pengfei Zhang, Yi Zhang · 2022 · European Journal of Medicinal Chemistry
  51. Phosphorylation of Ser1166 on GluN2B by PKA Is Critical to Synaptic NMDA Receptor Function and Ca2+Signaling in Spines
    Jessica A. Murphy, Ivar S. Stein, C. Geoffrey Lau, Rui T. Peixoto, Teresa K. Aman, Naoki Kaneko, Kelly A. Aromolaran, Jessica L. Saulnier, Gabriela Popescu, Bernardo Luis Sabatini et al. · 2014 · Journal of Neuroscience
  52. Signalling via glutamate and GLRs in Arabidopsis thaliana
    Matthias Weiland, Stefano Mancuso, František Baluška · 2015 · Functional Plant Biology
  53. Structural Mechanisms of Gating in Ionotropic Glutamate Receptors
    Edward C. Twomey, Alexander I. Sobolevsky · 2017 · Biochemistry
  54. γ-Aminobutyrate- and Glutamate-gated Chloride Channels as Targets of Insecticides
    Yoshihisa Ozoe · 2013 · Advances in insect physiology
  55. Activated CaMKII Couples GluN2B and Casein Kinase 2 to Control Synaptic NMDA Receptors
    Antonio Sanz-Clemente, John A. Gray, Kyle A. Ogilvie, Roger A. Nicoll, Katherine W. Roche · 2013 · Cell Reports
  56. Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: Focus on nicotine effects
    Francesco Pistillo, Francesco Clementi, Michèle Zoli, Cecilia Gotti · 2014 · Progress in Neurobiology
  57. Subunit-Selective Allosteric Inhibition of Glycine Binding to NMDA Receptors
    Kasper Bø Hansen, Kevin K. Ogden, Stephen F. Traynelis · 2012 · Journal of Neuroscience
  58. Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington’s Disease Models
    Vahri Beaumont, Sheng Zhong, Hai Lin, WenJin Xu, Amyaouch Bradaïa, Esther Steidl, Melanie Gleyzes, Kristian Wadel, Bruno Buisson, Fernando E. Padovan‐Neto et al. · 2016 · Neuron
  59. Phosphorylation-Dependent Regulation of Ca2+-Permeable AMPA Receptors During Hippocampal Synaptic Plasticity
    Alicia Purkey, Mark L. Dell’Acqua · 2020 · Frontiers in Synaptic Neuroscience
  60. Neto1 Is an Auxiliary Subunit of Native Synaptic Kainate Receptors
    Tang, M., Pelkey, K. A., Ng, D., Ivakine, E., McBain, C. J., Salter, M. W., McInnes, R. R. · 2011 · Journal of Neuroscience
  61. Structure of an agonist-bound ionotropic glutamate receptor
    Maria V. Yelshanskaya, Minfen Li, Alexander I. Sobolevsky · 2014 · Science
  62. Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition
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  63. The intersection of stress and reward: BNST modulation of aversive and appetitive states
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  64. Unmasking GluN1/GluN3A excitatory glycine NMDA receptors
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  65. Pharmacological Alternatives for the Treatment of Neurodegenerative Disorders: Wasp and Bee Venoms and Their Components as New Neuroactive Tools
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  67. A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists
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  69. Synaptic Neurotransmitter-Gated Receptors
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  70. Agonist binding to the NMDA receptor drives movement of its cytoplasmic domain without ion flow
    Kim Doré, Jonathan Aow, Roberto Malinow · 2015 · Proceedings of the National Academy of Sciences
  71. Developmental origin dictates interneuron AMPA and NMDA receptor subunit composition and plasticity
    Matta, Jose A, Pelkey, Kenneth A, Craig, Michael T, Chittajallu, Ramesh, Jeffries, Brian W, McBain, Chris J · 2013 · Nature Neuroscience
  72. NMDA-Type Glutamate Receptor Activation Promotes Vascular Remodeling and Pulmonary Arterial Hypertension
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  75. Stress-Induced Changes of Hippocampal NMDA Receptors: Modulation by Duloxetine Treatment
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  76. Hippocampal TNFα Signaling Contributes to Seizure Generation in an Infection-Induced Mouse Model of Limbic Epilepsy
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  77. Expanding Role of NMDA Receptor Antagonists in the Management of Pain
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  78. Anti-N-methyl-D-aspartate receptor encephalitis: A review of pathogenic mechanisms, treatment, prognosis
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  79. Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors
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  80. NMDA Receptors in Astrocytes: In Search for Roles in Neurotransmission and Astrocytic Homeostasis
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  81. GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine
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  82. Shaping the synaptic signal: molecular mobility inside and outside the cleft
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  83. Control of Assembly and Function of Glutamate Receptors by the Amino-Terminal Domain
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  84. Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design
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  85. Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8
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  89. Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-d-aspartate Receptor Subunit-Selective Modulators
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  100. AMPA receptor trafficking for postsynaptic potentiation
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