The Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels: From Biophysics to Pharmacology of a Unique Family of Ion Channels

Sartiani, Laura, Mannaioni, Guido, Masi, Alessio, Novella Romanelli, Maria, Cerbai, Elisabetta·2017·Pharmacological Reviews

Cites (497)

Items 401–491 of 491

  1. Propofol suppresses a hyperpolarization-activated inward current in rat hippocampal CA1 neurons
    Makoto Funahashi, Hitoshi Higuchi, Takuya Miyawaki, Masahiko Shimada, Ryuji Matsuo · 2001 · Neuroscience Letters
  2. Investigations into the bradycardic effects of UL-FS 49 (1,3,4,5-tetrahydro-7,8-dimethoxy-3-[3-[[2-(3,4-dimethoxyphenyl)ethyl] methylimino]propyl]-2H-3-benzazepin-2-on-hydrochloride) in isolated guinea pig atria.
    Christian Lillie, Walter Kobinger · 1986 · PubMed
  3. Methamphetamine blunts Ca2+currents and excitatory synaptic transmission through D1/5 receptor-mediated mechanisms in the mouse medial prefrontal cortex
    Betina González, María Celeste Rivero‐Echeto, Javier Andrés Muñiz, Jean Lud Cadet, Edgar García‐Rill, Francisco J. Urbano, Verónica Bisagno · 2015 · Addiction Biology
  4. Discovery of a novel series of selective HCN1 blockers
    Kelly J. McClure, Michael P. Maher, Nancy Wu, Sandra R. Chaplan, William A. Eckert, Dong Hyun Lee, Alan D. Wickenden, Michelle Hermann, Brett D. Allison, Natalie A. Hawryluk et al. · 2011 · Bioorganic & Medicinal Chemistry Letters
  5. Filamin A Promotes Dynamin-dependent Internalization of Hyperpolarization-activated Cyclic Nucleotide-gated Type 1 (HCN1) Channels and Restricts Ih in Hippocampal Neurons
    Yoav Noam, Markus U. Ehrengruber, Annie Koh, Paul Feyen, Erik M. M. Manders, Geoffrey Winston Abbott, Wytse Jan Wadman, Tallie Z. Baram · 2014 · Journal of Biological Chemistry
  6. Mathematical modelling of the action potential of human embryonic stem cell derived cardiomyocytes
    Michelangelo Paci, Laura Sartiani, Martina Del Lungo, Marisa E. Jaconi, Alessandro Mugelli, Elisabetta Cerbai, Stefano Severi · 2012 · BioMedical Engineering OnLine
  7. Cyclic Nucleotide Mapping of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels
    Stefan Möller, Andrea Alfieri, Daniela Bertinetti, Marco Aquila, Frank Schwede, Marco Lolicato, Holger Rehmann, Anna Moroni, Friedrich W. Herberg · 2014 · ACS Chemical Biology
  8. Hyperpolarization‐activated and cyclic nucleotide‐gated cation channel subunit 2 ion channels modulate synaptic transmission from nociceptive primary afferents containing substance P to secondary sensory neurons in laminae I–IIo of the rodent spinal dorsal horn
    Ildikó Papp, Péter Szűcs, Krisztina Holló, Ferenc Erdélyi, Gábor Szabó, Miklós Antal · 2006 · European Journal of Neuroscience
  9. Tramadol-induced block of hyperpolarization-activated cation current in rat pituitary lactotrophs
    Yen‐Chin Liu, Ya-Jean Wang, Peï-Yu Wu, Sheng‐Nan Wu · 2008 · Naunyn-Schmiedeberg s Archives of Pharmacology
  10. MPP+ ‐dependent inhibition of Ih reduces spontaneous activity and enhances EPSP summation in nigral dopamine neurons
    Alessio Masi, Roberto Narducci, Elisa Landucci, Flavio Moroni, Guido Mannaioni · 2013 · British Journal of Pharmacology
  11. Effect of Chronic Changes in Heart Rate on Congestive Heart Failure
    Krishnamurti Rao, Michael L. Fisher, Shawn Robinson, Stephen Ross Shorofsky, Stephen S. Gottlieb · 2007 · Journal of Cardiac Failure
  12. The case for the funny current and the calcium clock
    Michael R. Rosen, Joël Nargeot, Guy Salama · 2011 · Heart Rhythm
  13. Multiple inhibitory effects of zatebradine (UL-FS 49) on the electrophysiological properties of retinal rod photoreceptors
    Tomo-Oki Satoh, Masahiro Yamada · 2001 · Pflügers Archiv - European Journal of Physiology
  14. Functional characterization of hyperpolarization-activated cyclic nucleotide-gated channels in rat pancreatic β cells
    Yi Zhang, Yunfeng Liu, Jihong Qu, Alexandre B. Hardy, Nina Zhang, Jingyu Diao, Paul J. L. M. Strijbos, Robert G. Tsushima, Richard B. Robinson, Herbert Y. Gaisano et al. · 2009 · Journal of Endocrinology
  15. Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia
    Christian Schön, Sabrina Asteriti, Susanne Koch, Vithiyanjali Sothilingam, Marina Garcia Garrido, Naoyuki Tanimoto, Jochen Wolfgang Herms, Mathias W. Seeliger, Lorenzo Cangiano, Martin Biel et al. · 2016 · Human Molecular Genetics
  16. Dexmedetomidine: A Review of its Use for the Management of Pain, Agitation, and Delirium in the Intensive Care Unit
    Kevin E. Anger · 2013 · Current Pharmaceutical Design
  17. Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels and Pain
    John Dunlop, D. Vasilyev, P. Lu, Terri A. Cummons, Mark R. Bowlby · 2009 · Current Pharmaceutical Design
  18. Functional remodeling in post-myocardial infarcted rats: focus on beta-adrenoceptor subtypes
    Laura Sartiani, Petra DePaoli, Francesca Stillitano, Franck Aimond, Guy Vassort, A. Mugelli, Elisabetta Cerbai · 2006 · Journal of Molecular and Cellular Cardiology
  19. Suppression of the hyperpolarization-activated inward current contributes to the inhibitory actions of propofol on rat CA1 and CA3 pyramidal neurons
    Hitoshi Higuchi, Makoto Funahashi, Takuya Miyawaki, Yoshihiro Mitoh, Atsushi Kohjitani, Masahiko Shimada, Ryuji Matsuo · 2003 · Neuroscience Research
  20. The enhancement of HCN channel instantaneous current facilitated by slow deactivation is regulated by intracellular chloride concentration
    Pavel Mistrík, Alexander Pfeifer, Martin Biel · 2006 · Pflügers Archiv - European Journal of Physiology
  21. Minocycline inhibits hyperpolarization-activated currents in rat substantia gelatinosa neurons
    Nana Liu, Daying Zhang, Mengye Zhu, Shiwen Luo, Tao Liu · 2015 · Neuropharmacology
  22. Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure
    Yuko Yamada, Hideyuki Kinoshita, Koichiro Kuwahara, Yasuaki Nakagawa, Yoshihiro Kuwabara, Takeya Minami, Chinatsu Yamada, Junko Shibata, Kazuhiro Nakao, Kosai Cho et al. · 2014 · Cardiovascular Research
  23. High dendritic expression of Ih in the proximity of the axon origin controls the integrative properties of nigral dopamine neurons
    Dominique Engel, Vincent Seutin · 2015 · The Journal of Physiology
  24. Mechanisms of block of a human cloned potassium channel by the enantiomers of a new bradycardic agent: S‐16257‐2 and S‐16260‐2
    Eva Delpón, Carmen Valenzuela, Onésima Pérez, Laura Franqueza, Pilar Gay, Dirk J. Snyders, Juan Luis Tamargo · 1996 · British Journal of Pharmacology
  25. Updates on HCN Channels in the Heart: Function, Dysfunction and Pharmacology
    Laura Sartiani, María Novella Romanelli, Alessandro Mugelli, Elisabetta Cerbai · 2015 · Current Drug Targets
  26. Role of Dynamics in the Autoinhibition and Activation of the Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) Ion Channels
    Bryan VanSchouwen, Madoka Akimoto, Maryam Sayadi, Federico Fogolari, Giuseppe Melacini · 2015 · Journal of Biological Chemistry
  27. Use‐dependent block of Ih in mouse dorsal root ganglion neurons by sinus node inhibitors
    Adam L. Raes, Gerda Van de Vijver, Marnix Goethals, P.‐P. VAN BOGAERT · 1998 · British Journal of Pharmacology
  28. Investigation of Hyperpolarization-activated Cyclic Nucleotide-gated Channels in Interstitial Cells of Cajal of Human Bladder
    Xue Li, Yuxin Li, Xiujuan Han, Liping Yao, Jianlin Yuan, Weijun Qin, Fei Liu, He Wang · 2012 · Urology
  29. Age-associated expression of HCN channel isoforms in rat sinoatrial node
    Xin S. Huang, Pei Yang, Zhao Yang, Hong Zhang, Aiqun Ma · 2015 · Experimental Biology and Medicine
  30. Proteolytic Processing of HCN2 and Co-assembly with HCN4 in the Generation of Cardiac Pacemaker Channels
    Bin Ye, Jeanne M. Nerbonne · 2009 · Journal of Biological Chemistry
  31. Pharmacological modulation of the hyperpolarization-activated current (I f) in human atrial myocytes: focus on G protein-coupled receptors.
    G. Lonardo, E. Cerbai, S. Casini, G. Giunti, M. Bonacchi, F. Battaglia, B. Fiorani, P. Stefàno, G. Sani, A. Mugelli · 2005 · Journal of Molecular and Cellular Cardiology
  32. Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel
    Xinping Xu, Farzana Marni, Shengjun Wu, Zhuocheng Su, Faik N. Musayev, Sabisha Shrestha, Changan Xie, Weihua Gao, Qinglian Liu, Lei Zhou · 2012 · Structure
  33. Association between Reversal in the Expression of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channel and Age-Related Atrial Fibrillation
    Baopeng Tang · 2014 · Medical Science Monitor
  34. Molecular Regulation and Pharmacology of Pacemaker Channels
    Patrick Bois, Romain Guinamard, Antoun El Chemaly, Jean‐François Faivre, Jocelyn Bescond · 2007 · Current Pharmaceutical Design
  35. Quantitative Trait Loci and a Novel Genetic Candidate for Fear Learning
    Allison T. Knoll, Lindsay R. Halladay, Andrew Holmes, Pat R. Levitt · 2016 · Journal of Neuroscience
  36. Emerging role of ivabradine for rate control in atrial fibrillation
    Sarah L. Turley, Kerry E. Francis, Denise Lowe, William D. Cahoon · 2016 · Therapeutic Advances in Cardiovascular Disease
  37. HCN1 channels reduce the rate of exocytosis from a subset of cortical synaptic terminals
    Zhuo Huang, Gengyu Li, Carolina Aguado, Rafael Luján, Mala M. Shah · 2017 · Scientific Reports
  38. Ionic mechanisms underlying the negative chronotropic action of propofol on sinoatrial node automaticity in guinea pig heart
    Akiko Kojima, Yuki Ito, Hirotoshi Kitagawa, Hiroshi Matsuura · 2014 · British Journal of Pharmacology
  39. Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect
    Corinna Mattusch, Stephan Kratzer, Martina Buerge, Matthias Kreuzer, Tatiana Engel, Claudia Kopp, Martin Biel, Verena Hammelmann, Shui‐Wang Ying, Peter A. Goldstein et al. · 2015 · Anesthesiology
  40. Effect of HCN Channel Inhibition on Retinal Morphology and Function in Normal and Dystrophic Rodents
    Luca Della Santina, Muriel Bouly, A Asta, Gian Carlo Demontis, Luigi Cervetto, Claudia Gargini · 2010 · Investigative Ophthalmology & Visual Science
  41. Interstitial cell modulation of pyeloureteric peristalsis in the mouse renal pelvis examined using FIBSEM tomography and calcium indicators
    Hikaru Hashitani, Michael J. Nguyen, Haruka Noda, Retsu Mitsui, Ryuhei Higashi, Keisuke Ohta, Kei‐ichiro Nakamura, Richard J. Lang · 2017 · Pflügers Archiv - European Journal of Physiology
  42. Presence of functional hyperpolarisation-activated cyclic nucleotide-gated channels in clonal alpha cell lines and rat islet alpha cells
    Yaoyu Zhang, N. Zhang, Armen V. Gyulkhandanyan, Elaine Xu, Herbert Y. Gaisano, Michael B. Wheeler, Q. Wang · 2008 · Diabetologia
  43. Changes in hyperpolarization-activated cyclic nucleotide-gated channel expression and activity in bladder interstitial cells of Cajal from rats with detrusor overactivity
    Tianxing Deng, Qian Zhang, Qingqing Wang, Xiao Zhong, Longkun Li · 2015 · International Urogynecology Journal
  44. Inhibition of If in the atrioventricular node as a mechanism for dronedarone’s reduction in ventricular rate during atrial fibrillation
    Richard L. Verrier, Marcel Faraco Sobrado, Vitor Penteado Figueiredo Pagotto, Alexandre Fligelman Kanas, Ananda Dianni Machado, Bruno Butturi Varone, Lucas Faraco Sobrado, Bruce D. Nearing, Dewan Zeng, Luiz Belardinelli · 2013 · Heart Rhythm
  45. Cocaine sensitization inhibits the hyperpolarization-activated cation current Ih and reduces cell size in dopamine neurons of the ventral tegmental area
    Francisco Arencibia‐Albite, Rafael Vázquez, María Carolina Velásquez-Martínez, Carlos A. Jiménez‐Rivera · 2012 · Journal of Neurophysiology
  46. Lidocaine Inhibits HCN Currents in Rat Spinal Substantia Gelatinosa Neurons
    Tao Hu, Nana Liu, Minhua Lv, Long‐Xian Ma, Huizhen Peng, Sicong Peng, Tao Liu · 2016 · Anesthesia & Analgesia
  47. Spironolactone Regulates HCN Protein Expression Through Micro-RNA-1 in Rats With Myocardial Infarction
    Hua-Dong Yu, Shuang Xia, Zha Chengqin, Songbai Deng, Jianlin Du, Qiang She · 2015 · Journal of Cardiovascular Pharmacology
  48. Angiotensin II-NADPH oxidase-derived superoxide mediates diabetes-attenuated cell excitability of aortic baroreceptor neurons
    Yu‐Long Li, Hong Zheng · 2011 · American Journal of Physiology-Cell Physiology
  49. Preferential Inhibition of I h in Rat Trigeminal Ganglion Neurons by an Organic Blocker
    Damir Janigro, Melissa E. Martenson, Thomas Baumann · 1997 · The Journal of Membrane Biology
  50. Lidocaine Blocks the Hyperpolarization-activated Mixed Cation Current, I h, in Rat Thalamocortical Neurons
    Igor Putrenko, Stephan K. W. Schwarz · 2011 · Anesthesiology
  51. SK- and h-current contribute to the generation of theta-like resonance of rat substantia nigra pars compacta dopaminergic neurons at hyperpolarized membrane potentials
    Weining Xue, Yuan Wang, Shiming He, Xuelian Wang, Jun-Ling Zhu, Guodong Gao · 2011 · Brain Structure and Function
  52. Novel Role of KT5720 on Regulating Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Activity and Dorsal Root Ganglion Neuron Excitability
    Qiuping Cheng, Yanhong Zhou · 2013 · DNA and Cell Biology
  53. A Novel High-Throughput Screening Assay for HCN Channel Blocker Using Membrane Potential–Sensitive Dye and FLIPR
    Dmitry V. Vasilyev, Qin J. Shan, Yan T. Lee, Veronica Soloveva, Stanley P. Nawoschik, Edward J. Kaftan, John Dunlop, Scott C. Mayer, Mark R. Bowlby · 2009 · SLAS DISCOVERY
  54. Nedd4‐2 regulates surface expression and may affect N ‐glycosylation of hyperpolarization‐activated cyclic nucleotide‐gated (HCN)‐1 channels
    Wiebke Wilkars, Jessica Wollberg, Evita Mohr, Mieri Han, Dane M. Chetkovich, Robert Bähring, Roland A. Bender · 2014 · The FASEB Journal
  55. Hyperpolarization-activated, cyclic nucleotide-gated cation channels in Aplysia : Contribution to classical conditioning
    Qizong Yang, Pavlo Kuzyk, Igor Antonov, Caleb J. Bostwick, Andrea B. Kohn, Leonid L. Moroz, Robert D. Hawkins · 2015 · Proceedings of the National Academy of Sciences
  56. Treatment With Irbesartan Counteracts the Functional Remodeling of Ventricular Myocytes From Hypertensive Rats
    Elisabetta Cerbai, Petra De Paoli, Laura Sartiani, Giuseppe Lonardo, Alessandro Mugelli · 2003 · Journal of Cardiovascular Pharmacology
  57. Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening
    Leo C. T. Ng, Igor Putrenko, Victoria A. Baronas, Filip Van Petegem, Eric A. Accili · 2016 · Structure
  58. Modulation of the hyperpolarization-activated inward current (If) by antiarrhythmic agents in isolated human atrial myocytes
    Uta Charlotte Hoppe, Dirk J. Beuckelmann · 1998 · Naunyn-Schmiedeberg s Archives of Pharmacology
  59. Prenatal exposure to carbon monoxide delays postnatal cardiac maturation
    Laura Sartiani, Francesca Stillitano, Cristina Luceri, Silvia Suffredini, Simona Toti, Carlotta De Filippo, V. Cuomo, Maria Tattoli, Piero Dolara, Alessandro Mugelli et al. · 2010 · Laboratory Investigation
  60. Modulation of the pacemaker current If by β-adrenoceptor subtypes in ventricular myocytes isolated from hypertensive and normotensive rats
    Elisabetta Cerbai · 1999 · Cardiovascular Research
  61. Hyperpolarization-activated Cyclic Nucleotide-gated Channels May Contribute to Regional Anesthetic Effects of Lidocaine
    Cheng Zhou, Bowen Ke, Yi Zhao, Peng Liang, Daqing Liao, Tao Li, Jin Liu, Xiangdong Chen · 2014 · Anesthesiology
  62. PKA-independent activation of Ifby cAMP in mouse sinoatrial myocytes
    Joshua R. St. Clair, Zhandi Liao, Eric D. Larson, Catherine Proenza · 2013 · Channels
  63. SUMOylation of the Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 Increases Surface Expression and the Maximal Conductance of the Hyperpolarization-Activated Current
    Anna R. Parker, Meghyn A. Welch, Lori A. Forster, Sarah M. Tasneem, Janhavi Dubhashi, Deborah J. Baro · 2017 · Frontiers in Molecular Neuroscience
  64. Flavonoid Regulation of HCN2 Channels
    Anne E. Carlson, Joel C. Rosenbaum, Tinatin I. Brelidze, Rachel E. Klevit, William N. Zagotta · 2013 · Journal of Biological Chemistry
  65. Pharmacological characterization of the heartbeat in an extant vertebrate ancestor, the Pacific hagfish, Eptatretus stoutii
    Christopher M. Wilson, Anthony P. Farrell · 2012 · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
  66. Architecture of the HCN selectivity filter and control of cation permeation
    Vincenzo Macri, Damiano Angoli, Eric A. Accili · 2012 · Scientific Reports
  67. hERG potassium channel inhibition by ivabradine may contribute to QT prolongation and risk of torsades de pointes
    Jules C. Hancox, Dario Melgari, Christopher E. Dempsey, Kieran E. Brack, John S. Mitcheson, G. André Ng · 2015 · Therapeutic Advances in Drug Safety
  68. Dronedarone's Inhibition of If Current Is the Primary Mechanism Responsible for Its Bradycardic Effect
    Lucas Faraco Sobrado, Bruno Butturi Varone, Ananda Dianni Machado, Bruce D. Nearing, Dewan Zeng, Luiz Belardinelli, Richard L. Verrier · 2013 · Journal of Cardiovascular Electrophysiology
  69. The sensitivity of hyperpolarization-activated cation current (Ih) to propofol in rat area postrema neurons
    Makoto Funahashi, Yoshihiro Mitoh, Ryuji Matsuo · 2004 · Brain Research
  70. Developmental increase in hyperpolarization-activated current regulates intrinsic firing properties in rat vestibular ganglion cells
    Ryoichi Yoshimoto, Shinichi Iwasaki, Hideki Takago, Toshiaki Nakajima, Yoshinori Sahara, K Kitamura · 2014 · Neuroscience
  71. A hyperpolarization-activated, cyclic nucleotide-gated, (Ih-like) cationic current and HCN gene expression in renal inner medullary collecting duct cells
    Juan J. Bolívar, Dagoberto Tapia, Gabina Arenas-López, Mauricio Castañón-Arreola, Haydee Torres, Elvira Galarraga · 2008 · American Journal of Physiology-Cell Physiology
  72. Class III antiarrhythmic drugs (amiodarone, bretylium and sotalol) on action potentials and membrane currents in rabbit sino-atrial node preparations
    Hiroyasu Satoh · 1991 · Naunyn-Schmiedeberg s Archives of Pharmacology
  73. Effects of ZD7288, a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker, on term-pregnant rat uterine contractility in vitro
    Mohammed Alotaibi, Karima Kahlat, Taoufik Nedjadi, Laiche Djouhri · 2016 · Theriogenology
  74. Electromechanical Effects of Zatebradine on Isolated Guinea Pig Cardiac Preparations
    Onésima Pérez, Pilar Gay, Laura Franqueza, Rosalı́a Carrón, Carmen Valenzuela, Eva Delpón, Juan Luis Tamargo · 1995 · Journal of Cardiovascular Pharmacology
  75. Frequency dependence of CA3 spike phase response arising from h-current properties
    Mélodie Borel, Simone Guadagna, Hyun Jae Jang, Jeehyun Kwag, Ole Paulsen · 2013 · Frontiers in Cellular Neuroscience
  76. Lidocaine Inhibition of the Hyperpolarization-Activated Current (If) in Sinoatrial Myocytes
    Marcella Rocchetti, Alessandra Armato, Barbara Cavalieri, Maria Micheletti, Antonio Zaza · 1999 · Journal of Cardiovascular Pharmacology
  77. Mapping Ligand Interactions with the Hyperpolarization Activated Cyclic Nucleotide Modulated (HCN) Ion Channel Binding Domain Using a Soluble Construct
    Sean‐Patrick Scott, Patrick W. Shea, Stuart E. Dryer · 2007 · Biochemistry
  78. Probing the bradycardic drug binding receptor of HCN-encoded pacemaker channels
    Yau-Chi Chan, Kai Wang, Ka Wing Au, Chu-Pak Lau, Hung‐Fat Tse, Ronald A. Li · 2009 · Pflügers Archiv - European Journal of Physiology
  79. Cocaine sensitization increases subthreshold activity in dopamine neurons from the ventral tegmental area
    Francisco Arencibia‐Albite, Rafael Vázquez‐Torres, Carlos A. Jiménez‐Rivera · 2016 · Journal of Neurophysiology
  80. The membrane current (I(f)) in human atrial cells: implications for atrial arrhythmias
    Tobias Opthof A · 1998 · Data Archiving and Networked Services (DANS)
  81. Immunolocalization of hyperpolarization-activated cationic HCN1 and HCN3 channels in the rat nephron: regulation of HCN3 by potassium diets
    Zinaeli López-González, Cosete Ayala-Aguilera, Flavio Martínez-Morales, Othir Gidalti Galicia-Cruz, Carolina Salvador-Hernández, José Pedraza‐Chaverrí, Mara Medeiros-Domingo, Ana Hernández, Laura I. Escobar · 2015 · Histochemistry and Cell Biology
  82. Patch-clamp fluorometry–based channel counting to determine HCN channel conductance
    Chang Liu, Changan Xie, Khade Grant, Zhuocheng Su, Weihua Gao, Qinglian Liu, Lei Zhou · 2016 · The Journal of General Physiology
  83. A Leucine Zipper Motif Essential for Gating of Hyperpolarization-activated Channels
    Konstantin Wemhöner, Nicole Silbernagel, Stefanie Marzian, Michael F. Netter, Susanne Rinné, Phillip James Stansfeld, Niels Decher · 2012 · Journal of Biological Chemistry
  84. Dual effects of amiodarone on pacemaker currents in hypertrophied ventricular myocytes isolated from spontaneously hypertensive rats
    Hongxia Li, Yafeng Zhou, Bin Jiang, Xin Zhao, Xun Li, Xiangjun Yang, Wenping Jiang · 2014 · Clinical and Experimental Pharmacology and Physiology
  85. Novel electropharmacological activity of amiodarone on human HCN channels heterologously expressed in the Xenopus oocytes
    Xinrong Fan, Yongjun Chen, Pan Wu, Junlian Xing, Hui Chen, Tao Song, Jing Yang, Jun Zhang, Congxin Huang · 2011 · European Journal of Pharmacology
  86. Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Currents in Neurons
    Mala M. Shah · 2016 · Cold Spring Harbor Protocols
  87. Electrophysiology meets geometry
    Antonio Zaza · 2015 · EP Europace
  88. Editorial: History of 'specific bradycardic agents'
    Walter Kobinger · 1987 · European Heart Journal
  89. Local Loperamide Injection Reduces Mechanosensitivity of Rat Cutaneous, Nociceptive C-Fibers
    Matthias Ringkamp, Michael Tal, Timothy V. Hartke, Matthew Wooten, Alvin D. McKelvy, Brian P. Turnquist, Yun Guan, Richard A. Meyer, Srinivasa Naga Raja · 2012 · PLoS ONE
  90. Need for further studies on ivabradine in patients with persistent atrial fibrillation
    Jędrzej Kosiuk, Frank Lindemann, Gerhard Hindricks, Andreas Bollmann · 2016 · International Journal of Cardiology
  91. Propofol postsynaptically suppresses stellate neuron excitability in the entorhinal cortex by influencing the HCN and TREK-2 channels
    Xiaojun Li, Ke Pan, Dan Zhu, Yuping Li, Guocai Tao · 2016 · Neuroscience Letters