Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis

Cited by (293)

Items 201–293 of 293

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2. Myeloid-associated lipin-1 transcriptional co-regulatory activity is atheroprotective
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3. Multiple functions of MLKL in liver fibrosis, from necroptosis to hepatic stellate cell activation
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5. Targeting Programmed Cell Death as an Innovative Strategy Against Atherosclerosis: Potential of Natural Compound Supplements
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6. The Role of Macrophages in Atherosclerosis: Participants and Therapists
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7. Exploration and bioinformatic prediction for profile of mRNA bound to circular RNA BTBD7_hsa_circ_0000563 in coronary artery disease
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8. Metal–organic framework-based nanoplatforms for synergistic anti-atherosclerosis therapy by regulating the PI3K/AKT/MSR1 pathway in macrophages
   Chenlin Zeng, Zhiyou Peng, Sida Huang, Zhijue Xu, Zhaoxi Peng, Zhaoyu Wu, Jiahao Lei, Xing Zhang, Jinbao Qin, Kaichuang Ye et al. · 2024 · Nanoscale
9. Mixed Lineage Kinase Domain-Like Pseudokinase (MLKL) Gene Expression in Human Atherosclerosis with and without Type 2 Diabetes Mellitus
   Amany M. Kamal, Samer Ahmed Sebak, Eman F. Sanad · 2021 · Iranian Biomedical Journal
10. Data on leukocyte PDZK1 deficiency affecting macrophage apoptosis but not monocyte recruitment, cell proliferation, macrophage abundance or ER stress in atherosclerotic plaques of LDLR deficient mice
    Pei Yu, Alexander S. Qian, Kevin M. Chathely, Bernardo L. Trigatti · 2018 · Data in Brief
11. Necroptosis in obesity: a complex cell death event
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12. Determining the Significance of Coronary Plaque Lesions: Physiological Stenosis Severity and Plaque Characteristics
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13. 5-((7-Chloro-6-fluoro-1h-indol-3-yl) methyl)-3-methylimidazolidine-2,4-dione as a RIP1 inhibitor protects LPS/D-galactosamine-induced liver failure
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14. Apoptosis and Efferocytosis in Inflammatory Diseases
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15. Macrophage cannibalism: efferocytosis in atherosclerosis
    Amy A. Baxter, Ivan K. H. Poon, Denuja Karunakaran · 2025 · Current Opinion in Lipidology
16. The role of ZBP1 in eccentric exercise-induced skeletal muscle necroptosis
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17. Phosphoglycerate Mutase 5 Is Important Mediator for Instigating Arterial Lipid Accumulation and Aggravating Atherosclerosis
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18. The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease
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19. Distinct types of regulated cell death in atherosclerosis
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20. Dysregulated Lipid Metabolism as a Central Driver of Atherosclerotic Plaque Pathology
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21. Ligand-dependent interactions between SR-B1 and S1PR1 in macrophages and atherosclerotic plaques
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22. Apolipoprotein A1 deficiency increases macrophage apoptosis and necrotic core development in atherosclerotic plaques in a Bim-dependent manner
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23. AQP1 Affects Necroptosis by Targeting RIPK1 in Endothelial Cells of Atherosclerosis
    Ping Wang, Lin Zheng, Yusi Yang, Xinyang Yue, Jie Liu, Keyi Fan, Haonan Zhou, Honglin Dong · 2025 · Vascular Health and Risk Management
24. The antipsychotic drug thiothixene stimulates macrophages to clear pathogenic cells by inducing arginase 1 and continual efferocytosis
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25. Multifaceted cell death in atherosclerosis: Mechanisms, pathological impact, and therapeutic targeting
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26. PANoptosis and cardiovascular disease: The preventive role of exercise training
    Negin Kordi, Masoumeh Sanaei, Peyman Akraminia, Sajad Yavari, Ali Saydi, Fatemeh Khamis Abadi, Naser Heydari, Friedrich Jung, Sajad Karami · 2024 · Clinical Hemorheology and Microcirculation
27. Fine-tuning inflammation-resolution programs
    Gabrielle Fredman, Sudeshna Sadhu, Nicholas Rymut · 2016 · Current Opinion in Clinical Nutrition & Metabolic Care
28. Changes in plasma levels of RIPK1, RIPK3, and MLKL in patients with coronary atherosclerotic heart disease and its clinical predictive value.
    Zhen Xiao, Yinzhuang Zhang, Yuanyuan Kuang, Qilin Ma · 2020 · PubMed
29. Nontargeted Metabolomic Profiling of Huo-Tan-Chu-Shi Decoction in the Treatment of Coronary Heart Disease with Phlegm-damp Syndrome
    Zhaoying Liang, Qiaohuang Zeng, Xiaomin Ou, Jing Cai, Tao-Hua Lan, Weihui Lu · 2022 · Cardiology Research and Practice
30. Identification of necroptosis-related gene TRAF5 as potential target of diagnosing atherosclerosis and assessing its stability
    Zhanli Peng, Kangjie Wang, Shenming Wang, Ridong Wu, Yao Chen · 2023 · BMC Medical Genomics
31. Research Progress on Histone Deacetylases Regulating Programmed Cell Death in Atherosclerosis
    Gang Zhou, Yanfang Liu, Hui Wu, Dong Zhang, Qingzhuo Yang, Yi Li · 2023 · Journal of Cardiovascular Translational Research
32. Novel diagnostic biomarkers related to necroptosis and immune infiltration landscape in acute myocardial infarction
    Wenfa Wu, Hongxing Fan, Junlin Cen, Pei Huang, Guidong Li, Yanping Tan, Gen Liu, Baoshan Hong · 2024 · PeerJ
33. Zbp1 promotes atherosclerosis and lesion necrosis in mice
    Juying Han, Emmanuel Opoku, Gregory Brubaker, Jonathan D. Smith · 2025 · Atherosclerosis
34. Long non-coding RNA AK023617 orchestrates atherosclerosis by regulating the circadian rhythm of immunity-related GTPase family M protein in macrophages
    Rongzhe Lu, Hengxuan Cai, Yige Liu, Guanpeng Ma, Jiaxin Wang, Miao Yan, Zhenming Zhang, Bo Yu, Zhaoying Li, Shaohong Fang · 2024 · Non-coding RNA Research
35. Identification of potential therapeutic targets from bioinformatics analysis of necroptosis and immune infiltration in acute myocardial infarction
    Likang Ma, Keyuan Chen, Jiakang Li, Linfeng Xie, Zhaofeng Zhang, Mohammad Zarif, Tianci Chai, Qingsong Wu, Liangwan Chen, Zhihuang Qiu · 2024 · Journal of Cardiothoracic Surgery
36. Bibliometric analysis of publications on necroptosis from 2001 to 2021
    Yang Liu, Xiaojiang Zhou, Fangfei Wang, Cong Liu, Jun Xie, Le Luo Guan, Yong Xie · 2022 · Frontiers in Cell and Developmental Biology
37. MicroRNA Let-7g and Atherosclerosis Plaque Stabilization
    Rongping Yin, Chenlin Zhang, Yunying Hou, Xiaohua Wang · 2017 · World Journal of Cardiovascular Diseases
38. Microglial Necroptosis Mediated by RIPK3 Leads to Retinal Ganglion Cell Apoptosis Through the Release of FGF2 After Ischemia/Reperfusion
    Jianjun Liu, Anping Ma, Guangyi Huang, Wen Hu, Xin Yun Xu, Rong Huang, Yaguang Hu, Qiaochu Cheng, Yanlin Feng, Dan Ye et al. · 2025 · Journal of Molecular Neuroscience
39. From Single Cells to Targetable Immune Mechanisms in Congenital Heart Disease, Ischemic Heart Disease, and Abdominal Aortic Aneurysm
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40. Small-molecule modulators of the necroptotic pathway: A medicinal chemistry perspective
    De-Chang Li, Nannan Chen, Qi-Dong You, Xiaoli Xu · 2026 · European Journal of Medicinal Chemistry
41. Macrophage-associated kinase signaling in atherosclerosis – a systematic review
    Jana S. Müller, Emiel P. C. van der Vorst · 2026 · Cell Communication and Signaling
42. Macrophage extracellular traps accelerate atherosclerosis progression via Rap1 pathway-mediated necroptosis and phenotypic switching in vascular smooth muscle cells
    Suli Wang, Yajing Tang, Xinyi Yu, Zhenxing Liang, Dashuai Wang, Mingjie Xie, Liangjing Lu, Hai Liu · 2026 · Journal of Translational Medicine
43. CRISPR deletions in cell lines for reconstitution studies of pseudokinase function
    Annette V. Jacobsen, James M. Murphy · 2022 · Methods in enzymology on CD-ROM/Methods in enzymology
44. The Changing Face of Atherosclerosis
    Anna Meiliana, Andi Wijaya · 2023 · The Indonesian Biomedical Journal
45. SerpinA3N inhibits mitochondrial complex I activity to prevent neuron ferroptosis following cerebral ischemic stroke
    Xiansheng Liu, Gan Li, Yunlu Guo, Ruqi Li, Shilin Yi, Shenghao Ding, Jieqing Wan · 2025 · Experimental Neurology
46. Beyond cholesterol homeostasis: A novel role for PDZK1 in macrophage apoptosis and atherosclerosis
    Denuja Karunakaran · 2018 · Atherosclerosis
47. Fine Mapping of the Mouse Ath28 Locus Yields Three Atherosclerosis Modifying Sub-Regions
    Juying Han, Brian Ritchey, Emmanuel Opoku, Jonathan D. Smith · 2021 · Genes
48. Loss of MLKL Decreases Necrotic Core but Increases Macrophage Lipid Accumulation In Atherosclerosis
    A. Rasheed, S. Robichaud, My-anh Nguyen, M. Geoffrion, Mary Lynn Cottee, Taylor Dennison, A. Pietrangelo, Richard G. Lee, M. Ouimet, Katey J. Rayner · 2019 · bioRxiv
49. Nanoparticle endocytosis is driven by monocyte phenotype rather than nanoparticle size under high shear flow conditions
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50. A Novel Class of RIP1/RIP3 Dual Inhibitors
    Ting Zhou, Bo Liu · 2020 · Journal of Cellular Immunology
51. Membrane contact sites orchestrate cholesterol homeostasis that is central to vascular aging
    Wenjing Li, Yiyun Pang, Kehan Jin, Yuru Wang, Yujie Wu, Jichang Luo, Wenlong Xu, Xiao Zhang, Ran Xu, Tao Wang et al. · 2023 · WIREs Mechanisms of Disease
52. Macrophage senescence and programmed cell death in atherosclerosis: Mechanisms, cross-talk, and emerging therapeutic strategies
    Chenqin Xu, Chuang Ke, Yi-lang Zhong, Xiao-hui Yang, Miao-Miao Wang, Yongbing Cao, Jian Chen · 2026 · Ageing Research Reviews
53. Relationship between non-alcoholic fatty liver disease and cardiovascular disease
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54. Apoptosis Cellular Models in Cancer Therapeutics
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55. Dissection of TLR4-Induced Necroptosis Using Specific Inhibitors of Endocytosis and P38 MAPK
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56. Biology and pathology of atherosclerosis
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57. Inflammation and Atherosclerotic Cardiovascular Disease
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58. Macrophages in cardiovascular diseases
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59. A proposed enzyme-linked hydrogen peroxide radical assay system (HORAS)
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61. C1q/TNF-related protein 9 alleviates atherosclerosis by inhibiting ox-LDL-induced VSMC-derived foam cell necroptosis via the AMPK pathway
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62. Identification of potential therapeutic targets from bioinformatic analysis of necroptosis and immune infiltration in acute myocardial infarction
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63. Research Progress of Triglyceride-Glucose (TyG) Index in Atherosclerotic Cerebral Infarction
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64. Pitavastatin in the Prevention of Cardiovascular Disease in People Living with HIV: A Review
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65. Development and evolution of nuclear cardiology and cardiac PET in Canada
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66. Targeting SARS-CoV-2-Induced Cardiovascular Injury: Exploring the Potential of Ponatinib in Mitigating Cardiovascular Necroptosis in COVID-19
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67. Receptor-Interacting Protein Kinase 3 Augments Neuroinflammation by Facilitating Neutrophil Infiltration during an Ischemic Stroke
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68. The Process of Atheroma Growth, Vulnerability, and Rupture
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69. RIPK1, MLKL are Potential Biomarkers for Large Artery Atherosclerotic Acute Ischemic Stroke
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70. Integrative bioinformatics and cellular validation identify necroptosis-related genes as prognostic biomarkers in skin cutaneous melanoma
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71. Additional file 1 of Exploration and bioinformatic prediction for profile of mRNA bound to circular RNA BTBD7_hsa_circ_0000563 in coronary artery disease
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72. Additional file 1 of Identification of necroptosis-related gene TRAF5 as potential target of diagnosing atherosclerosis and assessing its stability
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73. Additional file 2 of Identification of necroptosis-related gene TRAF5 as potential target of diagnosing atherosclerosis and assessing its stability
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74. Additional file 1 of Targeted delivery of MerTK protein via cell membrane engineered nanoparticle enhances efferocytosis and attenuates atherosclerosis in diabetic ApoE−/− Mice
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75. Fusobacterium nucleatum exacerbates atherosclerosis progression via ceRNA network-mediated epigenetic reprogramming
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88. PANoptosis links gut dysbiosis to obstructive sleep apnea-associated atherosclerosis: a gut-vascular inflammatory axis
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