Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets

Neff, Ryan A., Wang, Minghui, Vatansever, Sezen, Guo, Lei, Ming, Chen, Wang, Qian, Wang, Erming, Horgusluoglu-Moloch, Emrin +16 more·2021·Science Advances
DOI 10.1126/sciadv.abb5398

Cited by (320)

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  40. Additional file 6 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis
    Yuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
  41. Additional file 5 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis
    Yuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
  42. Additional file 2 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis
    Yuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
  43. Additional file 4 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis
    Yuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
  44. Additional file 3 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis
    Yuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
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  63. Additional file 2 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  64. Additional file 4 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  65. Additional file 8 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis
    Yuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
  66. Additional file 11 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  67. Additional file 1 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease
    Kelley C. Larson, Lauren Herl Martens, Marconi, Michael, Christopher Dejesus, Suzanne Bruhn, Thomas A. Miller, Barbara A. Tate, Jonathan M. Levenson · 2024 · Figshare
  68. Additional file 6 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  69. Additional file 3 of Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity
    Elizabeth E. Evans, Mishra, Vikas, Crystal L. Mallow, Elaine M. Gersz, Leslie Balch, Alan P. Howell, Christine A. Reilly, Ernest Smith, Terrence Lee Fisher, Maurice Zauderer · 2022 · Figshare
  70. Additional file 10 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  71. Additional file 2 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease
    Kelley C. Larson, Lauren Herl Martens, Marconi, Michael, Christopher Dejesus, Suzanne Bruhn, Thomas A. Miller, Barbara A. Tate, Jonathan M. Levenson · 2024 · Figshare
  72. Additional file 8 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  73. Additional file 1 of Modulation of C5a–C5aR1 signaling alters the dynamics of AD progression
    Klébea Carvalho, Nicole D. Schartz, Gabriela Balderrama-Gutierrez, Liang, Heidi Y., Chu, Shu-Hui, Purnika Selvan, Ángela Gómez-Arboledas, Tiffany J. Petrisko, Fonseca, Maria I., Mortazavi, Ali et al. · 2022 · Figshare
  74. Additional file 5 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  75. Additional file 9 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis
    Yuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
  76. Additional file 4 of Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity
    Elizabeth E. Evans, Mishra, Vikas, Crystal L. Mallow, Elaine M. Gersz, Leslie Balch, Alan P. Howell, Christine A. Reilly, Ernest Smith, Terrence Lee Fisher, Maurice Zauderer · 2022 · Figshare
  77. Additional file 1 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  78. Additional file 1 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis
    Yuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
  79. Additional file 9 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  80. Additional file 3 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease
    Kelley C. Larson, Lauren Herl Martens, Marconi, Michael, Christopher Dejesus, Suzanne Bruhn, Thomas A. Miller, Barbara A. Tate, Jonathan M. Levenson · 2024 · Figshare
  81. Additional file 7 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesis
    Yuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
  82. Additional file 1 of Human brain organoids containing microglia that have arisen innately adapt to a β-amyloid challenge better than those in which microglia are integrated by co-culture
    Tyler J. Wenzel, Joseph D. Desjarlais, Darrell D. Mousseau · 2024 · Figshare
  83. Additional file 12 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  84. Additional file 3 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  85. Additional file 4 of Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease
    Kelley C. Larson, Lauren Herl Martens, Marconi, Michael, Christopher Dejesus, Suzanne Bruhn, Thomas A. Miller, Barbara A. Tate, Jonathan M. Levenson · 2024 · Figshare
  86. Additional file 7 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
  87. Additional file 2 of Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity
    Elizabeth E. Evans, Mishra, Vikas, Crystal L. Mallow, Elaine M. Gersz, Leslie Balch, Alan P. Howell, Christine A. Reilly, Ernest Smith, Terrence Lee Fisher, Maurice Zauderer · 2022 · Figshare
  88. Additional file 1 of Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity
    Elizabeth E. Evans, Mishra, Vikas, Crystal L. Mallow, Elaine M. Gersz, Leslie Balch, Alan P. Howell, Christine A. Reilly, Ernest Smith, Terrence Lee Fisher, Maurice Zauderer · 2022 · Figshare
  89. Additional file 13 of Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
    Alicia J. Barber, Carmen L. del Genio, Anna Beth Swain, Elizabeth M. Pizzi, Sarah C. Watson, Vedant N. Tapiavala, George J. Zanazzi, Arti B Gaur · 2024 · Figshare
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