Aerolysin nanopores decode digital information stored in tailored macromolecular analytes
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Informational polymers are deciphered by aerolysin pores.
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First experiments reading single-stranded synthetic biopolymers indicate that the reading step can be performed with biological nanopores without the use of an enzyme slowing down the translocation.
“First experiments reading single-stranded synthetic biopolymers indicate that the reading step can be performed with biological nanopores without the use of an enzyme slowing down the translocation.132”
From Emerging Approaches to DNA Data Storage: Challenges and Prospects (2022) · cites this paper as [132]
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References 43 · Cited by 97
- Authors
- Cao, C., Krapp, L. F., Al Ouahabi, A., König, N. F., Cirauqui, N., Radenovic, A., Lutz, J.-F., & Peraro, M. D.
- Affiliations
- SIB Swiss Institute of Bioinformatics (CH)
- Université de Strasbourg, Centre national de la recherche scientifique (CNRS), Institute Charles Sadron UPR22, 23 rue du Loess, 67034 Strasbourg Cedex 2, France.
- Centre National de la Recherche Scientifique (FR)
- Universidade Federal do Rio de Janeiro (BR)
- Institute of Bioengineering, School of Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
- Corresponding author
- Lutz, Jean-François
- Peraro, Matteo Dal
- ORCID
- Venue
- Science Advances
- Published
- 2020-12-11
- Volume
- 6
- Issue
- 50
- Pages
- eabc2661
- ISSN
- 2375-2548 (ISSN-L)
- PMC
- PMC7725454
- OpenAlex
- W3111689995
- Cited by
- 97
- References
- 43
- Citations by year
- 2026: 11 · 2025: 20 · 2024: 17 · 2023: 21 · 2022: 18 · 2021: 10
- FWCI
- 3.85
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Science Advances (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
- Funders
- Swiss National Science Foundation
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Nanopore and Nanochannel Transport Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Biological Computing
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Molecular Junctions and Nanostructures
- Keywords
- nanopore sequencing, digital data storage, synthetic polymers, biological data storage, anti-counterfeiting
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