The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Requirement of a Centrosomal Activity for Cell Cycle Progression Through G 1 into S Phase
Abstract
Centrosomes were microsurgically removed from BSC-1 African green monkey kidney cells before the completion of S phase. Karyoplasts (acentrosomal cells) entered and completed mitosis. However, postmitotic karyoplasts arrested before S phase, whereas adjacent control cells divided repeatedly. Postmitotic karyoplasts assembled a microtubule-organizing center containing γ-tubulin and pericentrin, but did not regenerate centrioles. These observations reveal the existence of an activity associated with core centrosomal structures—distinct from elements of the microtubule-organizing center—that is required for the somatic cell cycle to progress through G 1 into S phase. Once the cell is in S phase, these core structures are not needed for the G 2 -M phase transition.
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Citations
Cites
Centrosome-dependent exit of cytokinesis in animal cells
Piel, M., Nordberg, J., Euteneuer, U., & Bornens, M. (2001) · Science · doi:10.1126/science.1057330 · Cited by 389
Cited by
Li, J. B., Gerdes, J. M., Haycraft, C. J., Fan, Y., Teslovich, T. M., May-Simera, H., Li, H., Blacque, O. E., Li, L., Leitch, C. C., et al. (2004) · Cell · doi:10.1016/s0092-8674(04)00450-7 · Cited by 760
Centrosome aberrations: cause or consequence of cancer progression?
Nigg, E. A. (2002) · Nature Reviews Cancer · doi:10.1038/nrc924 · Cited by 732
Basto, R., Lau, J., Vinogradova, T., Gardiol, A., Woods, C. G., Khodjakov, A., & Raff, J. W. (2006) · Cell · doi:10.1016/j.cell.2006.05.025 · Cited by 686
Self-citationMeraldi, P. (2002) · The EMBO Journal · doi:10.1093/emboj/21.4.483 · Cited by 658
Centrosome Amplification Can Initiate Tumorigenesis in Flies
Basto, R., Brunk, K., Vinadogrova, T., Peel, N., Franz, A., Khodjakov, A., & Raff, J. W. (2008) · Cell · doi:10.1016/j.cell.2008.05.039 · Cited by 560
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Metadata
- Authors
- Hinchcliffe, E. H., Miller, F. J., Cham, M., Khodjakov, A., & Sluder, G.
- Venue
- Science
- Published
- 2001-02-23
- Volume
- 291
- Issue
- 5508
- Pages
- 1547-1550
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2012532095
- Cited by
- 339
- References
- 1
- FWCI
- 10.23
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hinchcliffe, E. H., Miller, F. J., Cham, M., Khodjakov, A., & Sluder, G. (2001). Requirement of a Centrosomal Activity for Cell Cycle Progression Through G 1 into S Phase. Science. https://doi.org/10.1126/science.1056866
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.