The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Complete Genome Sequence of a Virulent Isolate of Streptococcus pneumoniae
Abstract
The 2,160,837–base pair genome sequence of an isolate of Streptococcus pneumoniae , a Gram-positive pathogen that causes pneumonia, bacteremia, meningitis, and otitis media, contains 2236 predicted coding regions; of these, 1440 (64%) were assigned a biological role. Approximately 5% of the genome is composed of insertion sequences that may contribute to genome rearrangements through uptake of foreign DNA. Extracellular enzyme systems for the metabolism of polysaccharides and hexosamines provide a substantial source of carbon and nitrogen for S. pneumoniae and also damage host tissues and facilitate colonization. A motif identified within the signal peptide of proteins is potentially involved in targeting these proteins to the cell surface of low–guanine/cytosine (GC) Gram-positive species. Several surface-exposed proteins that may serve as potential vaccine candidates were identified. Comparative genome hybridization with DNA arrays revealed strain differences in S. pneumoniae that could contribute to differences in virulence and antigenicity.
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Dintilhac, A., Alloing, G., Granadel, C., & Claverys, J. (1997) · Molecular Microbiology · doi:10.1046/j.1365-2958.1997.5111879.x · Cited by 380
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Complete genome sequence of Lactobacillus plantarum WCFS1
Kleerebezem, M., Boekhorst, J., van Kranenburg, R., Molenaar, D., Kuipers, O. P., Leer, R., Tarchini, R., Peters, S. A., Sandbrink, H. M., Fiers, M. W. E. J., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337704100 · Cited by 1,472
Wu, M., Sun, L. V., Vamathevan, J., Riegler, M., Deboy, R., Brownlie, J. C., McGraw, E. A., Martin, W., Esser, C., Ahmadinejad, N., et al. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020069 · Cited by 851
“unusual nucleotide composition were performed as described previously (Tettelin et al. 2001).”
Self-citationStress responses in lactic acid bacteria
van de Guchte, M., Serror, P., Chervaux, C., Smokvina, T., Ehrlich, S. D., & Maguin, E. (2002) · Antonie van Leeuwenhoek · doi:10.1023/a:1020631532202 · Cited by 648
Streptococcus Adherence and Colonization
Nobbs, A. H., Lamont, R. J., & Jenkinson, H. F. (2009) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00014-09 · Cited by 657
Metadata
- Authors
- Tettelin, H., Nelson, K. E., Paulsen, I. T., Eisen, J. A., Read, T. D., Peterson, S., Heidelberg, J., DeBoy, R. T., Haft, D. H., Dodson, R. J., Durkin, A. S., Gwinn, M., Kolonay, J. F., Nelson, W. C., Peterson, J. D., Umayam, L. A., White, O., Salzberg, S. L., Lewis, M. R., Radune, D., Holtzapple, E., Khouri, H., Wolf, A. M., Utterback, T. R., Hansen, C. L., McDonald, L. A., Feldblyum, T. V., Angiuoli, S., Dickinson, T., Hickey, E. K., Holt, I. E., Loftus, B. J., Yang, F., Smith, H. O., Venter, J. C., Dougherty, B. A., Morrison, D. A., Hollingshead, S. K., & Fraser, C. M.
- Venue
- Science
- Published
- 2001-07-20
- Volume
- 293
- Issue
- 5529
- Pages
- 498-506
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2108360478
- Cited by
- 1,342
- References
- 1
- FWCI
- 67.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tettelin, H., Nelson, K. E., Paulsen, I. T., Eisen, J. A., Read, T. D., Peterson, S., Heidelberg, J., DeBoy, R. T., Haft, D. H., Dodson, R. J., Durkin, A. S., Gwinn, M., Kolonay, J. F., Nelson, W. C., Peterson, J. D., Umayam, L. A., White, O., Salzberg, S. L., Lewis, M. R., . . . Fraser, C. M. (2001). Complete Genome Sequence of a Virulent Isolate of Streptococcus pneumoniae. Science. https://doi.org/10.1126/science.1061217
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
