The DOI matches its Crossref record.
Resistance to an Herbivore Through Engineered Cyanogenic Glucoside Synthesis
Abstract
The entire pathway for synthesis of the tyrosine-derived cyanogenic glucoside dhurrin has been transferred from Sorghum bicolor to Arabidopsis thaliana . Here, we document that genetically engineered plants are able to synthesize and store large amounts of new natural products. The presence of dhurrin in the transgenic A. thaliana plants confers resistance to the flea beetle Phyllotreta nemorum , which is a natural pest of other members of the crucifer group, demonstrating the potential utility of cyanogenic glucosides in plant defense.
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Cited by
From waste products to ecochemicals: Fifty years research of plant secondary metabolism
Hartmann, T. (2007) · Phytochemistry · doi:10.1016/j.phytochem.2007.09.017 · Cited by 798
Plant resistance towards insect herbivores: a dynamic interaction
Gatehouse, J. A. (2002) · New Phytologist · doi:10.1046/j.1469-8137.2002.00519.x · Cited by 704
Tyrosine biosynthesis, metabolism, and catabolism in plants
Schenck, C. A., & Maeda, H. A. (2018) · Phytochemistry · doi:10.1016/j.phytochem.2018.02.003 · Cited by 286
Metabolon formation in dhurrin biosynthesis.
Nielsen, K. A., Tattersall, D. B., Jones, P. R., & Møller, B. L. (2008) · Phytochemistry · doi:10.1016/j.phytochem.2007.06.033 · Cited by 142
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Metadata
- Authors
- Tattersall, D. B., Bak, S., Jones, P. R., Olsen, C. E., Nielsen, J. K., Hansen, M. L., Høj, P. B., & Møller, B. L.
- Venue
- Science
- Published
- 2001-09-07
- Volume
- 293
- Issue
- 5536
- Pages
- 1826-1828
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2046499121
- Cited by
- 308
- References
- 0
- FWCI
- 16.78
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tattersall, D. B., Bak, S., Jones, P. R., Olsen, C. E., Nielsen, J. K., Hansen, M. L., Høj, P. B., & Møller, B. L. (2001). Resistance to an Herbivore Through Engineered Cyanogenic Glucoside Synthesis. Science. https://doi.org/10.1126/science.1062249
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