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The Genome of the Natural Genetic Engineer Agrobacterium tumefaciens C58
Abstract
The 5.67-megabase genome of the plant pathogen Agrobacterium tumefaciens C58 consists of a circular chromosome, a linear chromosome, and two plasmids. Extensive orthology and nucleotide colinearity between the genomes of A. tumefaciens and the plant symbiont Sinorhizobium meliloti suggest a recent evolutionary divergence. Their similarities include metabolic, transport, and regulatory systems that promote survival in the highly competitive rhizosphere; differences are apparent in their genome structure and virulence gene complement. Availability of the A. tumefaciens sequence will facilitate investigations into the molecular basis of pathogenesis and the evolutionary divergence of pathogenic and symbiotic lifestyles.
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Cited by
Caspi, R., Billington, R., Ferrer, L., Foerster, H., Fulcher, C. A., Keseler, I. M., Kothari, A., Krummenacker, M., Latendresse, M., Mueller, L. A., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkv1164 · Cited by 3,395
Self-citationAgrobacterium -Mediated Plant Transformation: the Biology behind the “Gene-Jockeying” Tool
Gelvin, S. B. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.1.16-37.2003 · Cited by 1,379
Buell, C. R., Joardar, V., Lindeberg, M., Selengut, J., Paulsen, I. T., Gwinn, M. L., Dodson, R. J., Deboy, R. T., Durkin, A. S., Kolonay, J. F., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1731982100 · Cited by 836
Self-citationAlegado, R. A., Brown, L. W., Cao, S., Dermenjian, R. K., Zuzow, R., Fairclough, S. R., Clardy, J., & King, N. (2012) · eLife · doi:10.7554/elife.00013 · Cited by 249
Molecular communication in the rhizosphere
Faure, D., Vereecke, D., & Leveau, J. H. J. (2009) · Plant and Soil · doi:10.1007/s11104-008-9839-2 · Cited by 199
Metadata
- Authors
- Wood, D. W., Setubal, J. C., Kaul, R., Monks, D. E., Kitajima, J. P., Okura, V. K., Zhou, Y., Chen, L., Wood, G. E., Almeida, N. F., Woo, L., Chen, Y., Paulsen, I. T., Eisen, J. A., Karp, P. D., Bovee, D., Chapman, P., Clendenning, J., Deatherage, G., Gillet, W., Grant, C., Kutyavin, T., Levy, R., Li, M.-J., McClelland, E., Palmieri, A., Raymond, C., Rouse, G., Saenphimmachak, C., Wu, Z., Romero, P., Gordon, D., Zhang, S., Yoo, H., Tao, Y., Biddle, P., Jung, M., Krespan, W., Perry, M., Gordon-Kamm, B., Liao, L., Kim, S., Hendrick, C., Zhao, Z.-Y., Dolan, M., Chumley, F., Tingey, S. V., Tomb, J.-F., Gordon, M. P., Olson, M. V., & Nester, E. W.
- Venue
- Science
- Published
- 2001-12-14
- Volume
- 294
- Issue
- 5550
- Pages
- 2317-2323
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2149184205
- Cited by
- 789
- References
- 0
- FWCI
- 69.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wood, D. W., Setubal, J. C., Kaul, R., Monks, D. E., Kitajima, J. P., Okura, V. K., Zhou, Y., Chen, L., Wood, G. E., Almeida, N. F., Woo, L., Chen, Y., Paulsen, I. T., Eisen, J. A., Karp, P. D., Bovee, D., Chapman, P., Clendenning, J., Deatherage, G., . . . Nester, E. W. (2001). The Genome of the Natural Genetic Engineer Agrobacterium tumefaciens C58. Science. https://doi.org/10.1126/science.1066804
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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