The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
The Distribution of Active Force Generators Controls Mitotic Spindle Position
Abstract
During unequal cell divisions a mitotic spindle is eccentrically positioned before cell cleavage. To determine the basis of the net force imbalance that causes spindle displacement in one-cell Caenorhabditis elegans embryos, we fragmented centrosomes with an ultraviolet laser. Analysis of the mean and variance of fragment speeds suggests that the force imbalance is due to a larger number of force generators pulling on astral microtubules of the posterior aster relative to the anterior aster. Moreover, activation of heterotrimeric guanine nucleotide– binding protein (Gprotein) α subunits is required to generate these astral forces.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Sachs, L. (1984) · Springer Series in Statistics · doi:10.1007/978-1-4612-5246-7 · Cited by 973
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
Gönczy, P., Echeverri, C., Oegema, K., Coulson, A., Jones, S. J. M., Copley, R. R., Duperon, J., Oegema, J., Brehm, M., Cassin, E., et al. (2000) · Nature · doi:10.1038/35042526 · Cited by 867
Self-citationThe variance of sodium current fluctuations at the node of Ranvier
Sigworth, F. J. (1980) · The Journal of Physiology · doi:10.1113/jphysiol.1980.sp013426 · Cited by 775
Dynamics and mechanics of the microtubule plus end
Howard, J., & Hyman, A. A. (2003) · Nature · doi:10.1038/nature01600 · Cited by 747
Self-citationSharp, D. J., Rogers, G. C., & Scholey, J. M. (2000) · Nature · doi:10.1038/35024000 · Cited by 592
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
Horvitz, H. R., & Herskowitz, I. (1992) · Cell · doi:10.1016/0092-8674(92)90468-r · Cited by 541
Grill, S. W., Gönczy, P., Stelzer, E. H. K., & Hyman, A. A. (2001) · Nature · doi:10.1038/35054572 · Cited by 509
Self-citationFormation of the first cleavage spindle in nematode embryos
Albertson, D. G. (1984) · Developmental Biology · doi:10.1016/0012-1606(84)90117-9 · Cited by 305
Translation of Polarity Cues into Asymmetric Spindle Positioning in Caenorhabditis elegans Embryos
Colombo, K., Grill, S. W., Kimple, R. J., Willard, F. S., Siderovski, D. P., & Gönczy, P. (2003) · Science · doi:10.1126/science.1084146 · Cited by 284
Self-citationMitosis: a history of division
Mitchison, T. J., & Salmon, E. D. (2001) · Nature Cell Biology · doi:10.1038/35050656 · Cited by 275
Cited by
Asymmetric cell divisions promote stratification and differentiation of mammalian skin
Lechler, T., & Fuchs, E. (2005) · Nature · doi:10.1038/nature03922 · Cited by 998
Probing Gene Expression in Live Cells, One Protein Molecule at a Time
Yu, J., Xiao, J., Ren, X., Lao, K., & Xie, X. S. (2006) · Science · doi:10.1126/science.1119623 · Cited by 918
Control of microtubule organization and dynamics: Two ends in the limelight
Akhmanova, A., & Steinmetz, M. O. (2015) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm4084 · Cited by 895
The PAR Proteins: Fundamental Players in Animal Cell Polarization
Goldstein, B., & Macara, I. G. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.10.007 · Cited by 758
Mechanisms of asymmetric cell division: flies and worms pave the way
Gönczy, P. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2388 · Cited by 489
Metadata
- Authors
- Grill, S. W., Howard, J., Schäffer, E., Stelzer, E. H. K., & Hyman, A. A.
- Venue
- Science
- Published
- 2003-07-25
- Volume
- 301
- Issue
- 5632
- Pages
- 518-521
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2007496445
- Cited by
- 379
- References
- 22
- FWCI
- 7.70
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Distribution of Active Force Generators Controls Mitotic Spindle Position. https://app.cochat.ai/papers/10.1126/science.1086560
- The paper
- Grill, S. W., Howard, J., Schäffer, E., Stelzer, E. H. K., & Hyman, A. A. (2003). The Distribution of Active Force Generators Controls Mitotic Spindle Position. Science. https://doi.org/10.1126/science.1086560
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
