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Cited by 464

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Chromosome Choreography: The Meiotic Ballet

Page, Scott L., Hawley, R. Scott·2003·Science

Abstract

The separation of homologous chromosomes during meiosis in eukaryotes is the physical basis of Mendelian inheritance. The core of the meiotic process is a specialized nuclear division (meiosis I) in which homologs pair with each other, recombine, and then segregate from each other. The processes of chromosome alignment and pairing allow for homolog recognition. Reciprocal meiotic recombination ensures meiotic chromosome segregation by converting sister chromatid cohesion into mechanisms that hold homologous chromosomes together. Finally, the ability of sister kinetochores to orient to a single pole at metaphase I allows the separation of homologs to two different daughter cells. Failures to properly accomplish this elegant chromosome dance result in aneuploidy, a major cause of miscarriage and birth defects in human beings.

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Metadata

Authors
Page, S. L., & Hawley, R. S.
Venue
Science
Published
2003-08-08
Volume
301
Issue
5634
Pages
785-789
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2001396107
Cited by
464
References
1
FWCI
9.27
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Chromosome Choreography: The Meiotic Ballet. https://app.cochat.ai/papers/10.1126/science.1086605
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Page, S. L., & Hawley, R. S. (2003). Chromosome Choreography: The Meiotic Ballet. Science. https://doi.org/10.1126/science.1086605

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