The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
RNA Polymerase IV Directs Silencing of Endogenous DNA
Abstract
Plants encode subunits for a fourth RNA polymerase (Pol IV) in addition to the well-known DNA-dependent RNA polymerases I, II, and III. By mutation of the two largest subunits (NRPD1a and NRPD2), we show that Pol IV silences certain transposons and repetitive DNA in a short interfering RNA pathway involving RNA-dependent RNA polymerase 2 and Dicer-like 3. The existence of this distinct silencing polymerase may explain the paradoxical involvement of an RNA silencing pathway in maintenance of transcriptional silencing.
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Citations
Cites
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
Initiative, T. A. G. (2000) · Nature · doi:10.1038/35048692 · Cited by 9,301
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
Cramer, P., Bushnell, D. A., & Kornberg, R. D. (2001) · Science · doi:10.1126/science.1059493 · Cited by 1,247
Cited by
MicroRNAs AND THEIR REGULATORY ROLES IN PLANTS
Jones-Rhoades, M. W., Bartel, D. P., & Bartel, B. (2006) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105218 · Cited by 2,686
Transposable elements and the epigenetic regulation of the genome
Slotkin, R. K., & Martienssen, R. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2072 · Cited by 2,044
Gardening the genome: DNA methylation in Arabidopsis thaliana
Chan, S. W.-L., Henderson, I. R., & Jacobsen, S. E. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1601 · Cited by 891
Small RNAs as Guardians of the Genome
Malone, C. D., & Hannon, G. J. (2009) · Cell · doi:10.1016/j.cell.2009.01.045 · Cited by 836
Epigenetic inheritance in plants
Henderson, I. R., & Jacobsen, S. E. (2007) · Nature · doi:10.1038/nature05917 · Cited by 835
Metadata
- Authors
- Herr, A. J., Jensen, M. B., Dalmay, T., & Baulcombe, D. C.
- Venue
- Science
- Published
- 2005-04
- Volume
- 308
- Issue
- 5718
- Pages
- 118-120
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2019471731
- Cited by
- 717
- References
- 2
- FWCI
- 70.74
- Type
- journal article
- Language
- en
- Open access
- closed
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- Herr, A. J., Jensen, M. B., Dalmay, T., & Baulcombe, D. C. (2005). RNA Polymerase IV Directs Silencing of Endogenous DNA. Science. https://doi.org/10.1126/science.1106910
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.