The DOI matches its Crossref record.
BZR1 Is a Transcriptional Repressor with Dual Roles in Brassinosteroid Homeostasis and Growth Responses
Open accessAbstract
Brassinosteroid (BR) homeostasis and signaling are crucial for normal growth and development of plants. BR signaling through cell-surface receptor kinases and intracellular components leads to dephosphorylation and accumulation of the nuclear protein BZR1. How BR signaling regulates gene expression, however, remains unknown. Here we show that BZR1 is a transcriptional repressor that has a previously unknown DNA binding domain and binds directly to the promoters of feedback-regulated BR biosynthetic genes. Microarray analyses identified additional potential targets of BZR1 and illustrated, together with physiological studies, that BZR1 coordinates BR homeostasis and signaling by playing dual roles in regulating BR biosynthesis and downstream growth responses.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Kim, T.-W., Guan, S., Sun, Y., Deng, Z., Tang, W., Shang, J.-X., Sun, Y., Burlingame, A. L., & Wang, Z.-Y. (2009) · Nature Cell Biology · doi:10.1038/ncb1970 · Cited by 693
Self-citationGlobal Analysis of DELLA Direct Targets in Early Gibberellin Signaling in Arabidopsis
Zentella, R., Zhang, Z.-L., Park, M., Thomas, S. G., Endo, A., Murase, K., Fleet, C. M., Jikumaru, Y., Nambara, E., Kamiya, Y., et al. (2007) · The Plant Cell · doi:10.1105/tpc.107.054999 · Cited by 678
Wang, X., & Chory, J. (2006) · Science · doi:10.1126/science.1127593 · Cited by 549
Brassinosteroids control meristem size by promoting cell cycle progression in Arabidopsis roots
González-García, M.-P., Vilarrasa-Blasi, J., Zhiponova, M., Divol, F., Mora-García, S., Russinova, E., & Caño-Delgado, A. I. (2011) · Development · doi:10.1242/dev.057331 · Cited by 522
Brassinosteroid Signaling Network and Regulation of Photomorphogenesis
Wang, Z.-Y., Bai, M.-Y., Oh, E., & Zhu, J.-Y. (2012) · Annual Review of Genetics · doi:10.1146/annurev-genet-102209-163450 · Cited by 490
Self-citation
Metadata
- Authors
- He, J.-X., Gendron, J. M., Sun, Y., Gampala, S. S. L., Gendron, N., Sun, C. Q., & Wang, Z.-Y.
- Venue
- Science
- Published
- 2005-03-11
- Volume
- 307
- Issue
- 5715
- Pages
- 1634-1638
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2049195203
- Cited by
- 864
- References
- 0
- FWCI
- 26.00
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: BZR1 Is a Transcriptional Repressor with Dual Roles in Brassinosteroid Homeostasis and Growth Responses. https://app.cochat.ai/papers/10.1126/science.1107580
- The paper
- He, J.-X., Gendron, J. M., Sun, Y., Gampala, S. S. L., Gendron, N., Sun, C. Q., & Wang, Z.-Y. (2005). BZR1 Is a Transcriptional Repressor with Dual Roles in Brassinosteroid Homeostasis and Growth Responses. Science. https://doi.org/10.1126/science.1107580
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
