The DOI matches its Crossref record.
FKF1 F-Box Protein Mediates Cyclic Degradation of a Repressor of CONSTANS in Arabidopsis
Abstract
The temporal control of CONSTANS (CO) expression and activity is a key mechanism in photoperiodic flowering in Arabidopsis . FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1) protein regulates CO transcription, although the molecular mechanism is unknown. We demonstrate here that FKF1 controls the stability of a Dof transcription factor, CYCLING DOF FACTOR 1 (CDF1). FKF1 physically interacts with CDF1, and CDF1 protein is more stable in fkf1 mutants. Plants with elevated levels of CDF1 flower late and have reduced expression of CO. CDF1 and CO are expressed in the same tissues, and CDF1 binds to the CO promoter. Thus, FKF1 controls daily CO expression in part by degrading CDF1, a repressor of CO transcription.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Phototropin Blue-Light Receptors
Christie, J. M. (2007) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.58.032806.103951 · Cited by 937
Seasonal and developmental timing of flowering
Amasino, R. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04148.x · Cited by 894
Stomatal Patterning and Differentiation by Synergistic Interactions of Receptor Kinases
Shpak, E. D., McAbee, J. M., Pillitteri, L. J., & Torii, K. U. (2005) · Science · doi:10.1126/science.1109710 · Cited by 586
Decoding of Light Signals by Plant Phytochromes and Their Interacting Proteins
Bae, G., & Choi, G. (2008) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.59.032607.092859 · Cited by 490
Phytochrome Interacting Factors: central players in phytochrome-mediated light signaling networks
Castillon, A., Shen, H., & Huq, E. (2007) · Trends in Plant Science · doi:10.1016/j.tplants.2007.10.001 · Cited by 470
Metadata
- Authors
- Imaizumi, T., Schultz, T. F., Harmon, F. G., Ho, L. A., & Kay, S. A.
- Venue
- Science
- Published
- 2005-07-08
- Volume
- 309
- Issue
- 5732
- Pages
- 293-297
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1967008937
- Cited by
- 777
- References
- 0
- FWCI
- 41.30
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: FKF1 F-Box Protein Mediates Cyclic Degradation of a Repressor of CONSTANS in Arabidopsis. https://app.cochat.ai/papers/10.1126/science.1110586
- The paper
- Imaizumi, T., Schultz, T. F., Harmon, F. G., Ho, L. A., & Kay, S. A. (2005). FKF1 F-Box Protein Mediates Cyclic Degradation of a Repressor of CONSTANS in Arabidopsis. Science. https://doi.org/10.1126/science.1110586
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
