The DOI matches its Crossref record.
Autophagic Fungal Cell Death Is Necessary for Infection by the Rice Blast Fungus
Abstract
Rice blast is caused by the fungus Magnaporthe grisea , which elaborates specialized infection cells called appressoria to penetrate the tough outer cuticle of the rice plant Oryza sativa . We found that the formation of an appressorium required, sequentially, the completion of mitosis, nuclear migration, and death of the conidium (fungal spore) from which the infection originated. Genetic intervention during mitosis prevented both appressorium development and conidium death. Impairment of autophagy, by the targeted mutation of the MgATG8 gene, arrested conidial cell death but rendered the fungus nonpathogenic. Thus, the initiation of rice blast requires autophagic cell death of the conidium.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 18
- 10.1146/annurev.py.29.090191.002303 · DOI · Paper page
- 10.1038/nature03449 · DOI · Paper page
- 10.1042/BST0330384 · DOI
- 10.1146/annurev.micro.57.030502.090957 · DOI · Paper page
- 10.1126/science.239.4837.288 · DOI · Paper page
- 10.1139/b90-044 · DOI · Paper page
- 10.1038/38418 · DOI · Paper page
- 10.1073/pnas.88.24.11281 · DOI · Paper page
- 10.1128/EC.2.2.341-350.2003 · doi:10.1128/ec.2.2.341-350.2003
- 10.1101/gad.10.21.2696 · DOI · Paper page
- 10.1016/0014-4827(76)90480-8 · doi:10.1016/0014-4827(76)90480-8
- 10.1016/0092-8674(88)90513-2 · DOI · Paper page
- 10.1074/jbc.270.30.18110 · doi:10.1074/jbc.270.30.18110
- 10.1093/emboj/17.13.3597 · DOI · Paper page
- A. Biederbick, H. F. Kern, H. P. Elsasser, Eur. J. Cell Biol.66, 3 (1995).
- 10.1111/j.1365-313X.2005.02396.x · DOI · Paper page
- 10.1146/annurev.genet.38.072902.093051 · DOI · Paper page
- We thank J. R. Xu and S. A. Osmani for the H3:eGFP strain of M. grisea and SO6 strain of A. nidulans respectively. We thank C. Hawes and B. Martin (Oxford Brookes University Oxon UK) for cryofixation and freeze substitution work and J. Jenkinson for critical reading of the paper. This work was supported by a grant to N.J.T. from the Leverhulme Trust.
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy · doi:10.1080/15548627.2015.1100356 · Cited by 5,894
Self-citationGuidelines for the use and interpretation of assays for monitoring autophagy
Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy · doi:10.4161/auto.19496 · Cited by 3,996
Self-citationGuidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy · doi:10.1080/15548627.2020.1797280 · Cited by 2,897
Under pressure: investigating the biology of plant infection by Magnaporthe oryzae
Wilson, R. A., & Talbot, N. J. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2032 · Cited by 1,085
Self-citationArchitecture of the dynamic fungal cell wall
Gow, N. A. R., & Lenardon, M. D. (2023) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00796-9 · Cited by 447
Metadata
- Authors
- Veneault-Fourrey, C., Barooah, M., Egan, M., Wakley, G., & Talbot, N. J.
- Venue
- Science
- Published
- 2006-04-28
- Volume
- 312
- Issue
- 5773
- Pages
- 580-583
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2061414976
- Cited by
- 530
- References
- 0
- FWCI
- 8.35
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Autophagic Fungal Cell Death Is Necessary for Infection by the Rice Blast Fungus. https://app.cochat.ai/papers/10.1126/science.1124550
- The paper
- Veneault-Fourrey, C., Barooah, M., Egan, M., Wakley, G., & Talbot, N. J. (2006). Autophagic Fungal Cell Death Is Necessary for Infection by the Rice Blast Fungus. Science. https://doi.org/10.1126/science.1124550
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
