The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Crystal Structure of the Rabies Virus Nucleoprotein-RNA Complex
Abstract
Negative-strand RNA viruses condense their genome into a helical nucleoprotein-RNA complex, the nucleocapsid, which is packed into virions and serves as a template for the RNA-dependent RNA polymerase complex. The crystal structure of a recombinant rabies virus nucleoprotein-RNA complex, organized in an undecameric ring, has been determined at 3.5 angstrom resolution. Polymerization of the nucleoprotein is achieved by domain exchange between protomers, with flexible hinges allowing nucleocapsid formation. The two core domains of the nucleoprotein clamp around the RNA at their interface and shield it from the environment. RNA sequestering by nucleoproteins is likely a common mechanism used by negative-strand RNA viruses to protect their genomes from the innate immune response directed against viral RNA in human host cells at certain stages of an infectious cycle.
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Cites
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Self-citation
Cited by
Current status of rabies and prospects for elimination
Fooks, A. R., Banyard, A. C., Horton, D. L., Johnson, N., McElhinney, L. M., & Jackson, A. C. (2014) · The Lancet · doi:10.1016/s0140-6736(13)62707-5 · Cited by 579
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Sequence-specific binding of single-stranded RNA: is there a code for recognition?
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RNA interference against viruses: strike and counterstrike
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Structure Unifies the Viral Universe
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Metadata
- Authors
- Albertini, A. A. V., Wernimont, A. K., Muziol, T., Ravelli, R. B. G., Clapier, C. R., Schoehn, G., Weissenhorn, W., & Ruigrok, R. W. H.
- Venue
- Science
- Published
- 2006-07-21
- Volume
- 313
- Issue
- 5785
- Pages
- 360-363
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2021527318
- Cited by
- 332
- References
- 13
- FWCI
- 13.28
- Type
- journal article
- Language
- en
- Open access
- closed
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- Albertini, A. A. V., Wernimont, A. K., Muziol, T., Ravelli, R. B. G., Clapier, C. R., Schoehn, G., Weissenhorn, W., & Ruigrok, R. W. H. (2006). Crystal Structure of the Rabies Virus Nucleoprotein-RNA Complex. Science. https://doi.org/10.1126/science.1125280
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