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Cited by 818

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis

Open access
Carlton, Jane M., Hirt, Robert P., Silva, Joana C., Delcher, Arthur L., Schatz, Michael, Zhao, Qi, Wortman, Jennifer R., Bidwell, Shelby L., Alsmark, U. Cecilia M., Besteiro, Sébastien, Sicheritz-Ponten, Thomas, Noel, Christophe J., Dacks, Joel B., Foster, Peter G., Simillion, Cedric, Van de Peer, Yves, Miranda-Saavedra, Diego, Barton, Geoffrey J., Westrop, Gareth D., Müller, Sylke, Dessi, Daniele, Fiori, Pier Luigi, Ren, Qinghu, Paulsen, Ian, Zhang, Hanbang, Bastida-Corcuera, Felix D., Simoes-Barbosa, Augusto, Brown, Mark T., Hayes, Richard D., Mukherjee, Mandira, Okumura, Cheryl Y., Schneider, Rachel, Smith, Alias J., Vanacova, Stepanka, Villalvazo, Maria, Haas, Brian J., Pertea, Mihaela, Feldblyum, Tamara V., Utterback, Terry R., Shu, Chung-Li, Osoegawa, Kazutoyo, de Jong, Pieter J., Hrdy, Ivan, Horvathova, Lenka, Zubacova, Zuzana, Dolezal, Pavel, Malik, Shehre-Banoo, Logsdon, John M., Henze, Katrin, Gupta, Arti, Wang, Ching C., Dunne, Rebecca L., Upcroft, Jacqueline A., Upcroft, Peter, White, Owen, Salzberg, Steven L., Tang, Petrus, Chiu, Cheng-Hsun, Lee, Ying-Shiung, Embley, T. Martin, Coombs, Graham H., Mottram, Jeremy C., Tachezy, Jan, Fraser-Liggett, Claire M., Johnson, Patricia J.·2007·Science
DOI 10.1126/science.1132894
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Abstract

We describe the genome sequence of the protist Trichomonas vaginalis , a sexually transmitted human pathogen. Repeats and transposable elements comprise about two-thirds of the ∼160-megabase genome, reflecting a recent massive expansion of genetic material. This expansion, in conjunction with the shaping of metabolic pathways that likely transpired through lateral gene transfer from bacteria, and amplification of specific gene families implicated in pathogenesis and phagocytosis of host proteins may exemplify adaptations of the parasite during its transition to a urogenital environment. The genome sequence predicts previously unknown functions for the hydrogenosome, which support a common evolutionary origin of this unusual organelle with mitochondria.

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Metadata

Authors
Carlton, J. M., Hirt, R. P., Silva, J. C., Delcher, A. L., Schatz, M., Zhao, Q., Wortman, J. R., Bidwell, S. L., Alsmark, U. C. M., Besteiro, S., Sicheritz-Ponten, T., Noel, C. J., Dacks, J. B., Foster, P. G., Simillion, C., Van de Peer, Y., Miranda-Saavedra, D., Barton, G. J., Westrop, G. D., Müller, S., Dessi, D., Fiori, P. L., Ren, Q., Paulsen, I., Zhang, H., Bastida-Corcuera, F. D., Simoes-Barbosa, A., Brown, M. T., Hayes, R. D., Mukherjee, M., Okumura, C. Y., Schneider, R., Smith, A. J., Vanacova, S., Villalvazo, M., Haas, B. J., Pertea, M., Feldblyum, T. V., Utterback, T. R., Shu, C.-L., Osoegawa, K., de Jong, P. J., Hrdy, I., Horvathova, L., Zubacova, Z., Dolezal, P., Malik, S.-B., Logsdon, J. M., Henze, K., Gupta, A., Wang, C. C., Dunne, R. L., Upcroft, J. A., Upcroft, P., White, O., Salzberg, S. L., Tang, P., Chiu, C.-H., Lee, Y.-S., Embley, T. M., Coombs, G. H., Mottram, J. C., Tachezy, J., Fraser-Liggett, C. M., & Johnson, P. J.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2007-01-12
Volume
315
Issue
5809
Pages
207-212
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.1132894
OpenAlex
W2163524749
Cited by
818
References
2
FWCI
56.09
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis. https://app.cochat.ai/papers/10.1126/science.1132894
The paper
Carlton, J. M., Hirt, R. P., Silva, J. C., Delcher, A. L., Schatz, M., Zhao, Q., Wortman, J. R., Bidwell, S. L., Alsmark, U. C. M., Besteiro, S., Sicheritz-Ponten, T., Noel, C. J., Dacks, J. B., Foster, P. G., Simillion, C., Van de Peer, Y., Miranda-Saavedra, D., Barton, G. J., Westrop, G. D., . . . Johnson, P. J. (2007). Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis. Science. https://doi.org/10.1126/science.1132894

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.