Dangers In and Out
Abstract
The immune system relies on specific signaling molecules to dampen its response to injury while maintaining the capacity to fight infection.
Integrity signals
Registry
Cites
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Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Inflammatory cell recruitment and activation at wound sites are driven by multiple signals, including factors released by degranulating platelets and by DAMPs and PAMPs from damaged cells and microbes.
“Inflammatory cell recruitment and activation are a consequence of many signals that occur at the wound site. Some of the earliest signals include factors released by degranulating platelets (23) and by damage- and pathogen-associated molecular patterns (DAMPs and PAMPs, respectively) where cells are damaged and microbes gain access (107).”
From Wound repair and regeneration: Mechanisms, signaling, and translation (2014) · cites this paper as [107]
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References 13 · Cited by 117
- Authors
- Bianchi, M. E., & Manfredi, A. A.
- Affiliations
- Vita-Salute San Raffaele University (IT)
- Venue
- Science
- Published
- 2009-03-27
- Volume
- 323
- Issue
- 5922
- Pages
- 1683-1684
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1495991289
- Cited by
- 117
- References
- 13
- Citations by year
- 2024: 5 · 2023: 2 · 2022: 1 · 2021: 5 · 2020: 5 · 2019: 4 · 2018: 5 · 2017: 6 · 2016: 8 · 2015: 9 · 2014: 15 · 2013: 14 · 2012: 12
- FWCI
- 5.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Health Sciences › Medicine › Oncology › Cytokine Signaling Pathways and Interactions
- Life Sciences › Immunology and Microbiology › Immunology › Inflammation biomarkers and pathways
- Keywords
- immune regulation, injury response, infection immunity, immune tolerance
- MeSH terms
- Animals, Immunity, Immunity, Innate, Infections, Inflammation, Liver, Necrosis, Receptors, Antigen, B-Cell, Wounds and Injuries, Signal Transduction, Autoimmunity, HMGB1 Protein, Lectins, Receptors, Pattern Recognition, Mice, CD24 Antigen, Sialic Acid Binding Immunoglobulin-like Lectins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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