The Mechanism for Activation of GTP Hydrolysis on the Ribosome
Cited by (360)
Items 101–200 of 360
- Archaeal ribosomal stalk protein interacts with translation factors in a nucleotide-independent manner via its conserved C terminusNaoko Nomura, Takayoshi Honda, Kentaro Baba, Takao Naganuma, Takehito Tanzawa, Fumio Arisaka, Masanori Noda, Susumu Uchiyama, Isao Tanaka, Min Yao et al. · 2012 · Proceedings of the National Academy of Sciences
- Elongation factor-Tu can repetitively engage aminoacyl-tRNA within the ribosome during the proofreading stage of tRNA selectionJustin C. Morse, Dylan J. Girodat, Benjamin J. Burnett, Mikael Holm, Roger B. Altman, Karissa Y. Sanbonmatsu, Hans‐Joachim Wieden, Scott C. Blanchard · 2020 · Proceedings of the National Academy of Sciences
- The Busiest of All Ribosomal Assistants: Elongation Factor TuDarius Kavaliauskas, Poul Nissen, Charlotte Rohde Knudsen · 2012 · Biochemistry
- Crystal structure of eukaryotic ribosome and its complexes with inhibitorsGulnara Zh. Yusupova, Marat Yusupov · 2017 · Philosophical Transactions of the Royal Society B Biological Sciences
- Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting ComplexKlemens Wild, Gert Bange, Domantas Motiejunas, Judith F. Kribelbauer-Swietek, Astrid Hendricks, Bernd Segnitz, Rebecca C. Wade, Irmgard Sinning · 2016 · Journal of Molecular Biology
- Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediateAmal Seffouh, Nikhil Jain, Dushyant Jahagirdar, Kaustuv Basu, Aida Razi, Xiaodan Ni, Alba Guarné, Robert A. Britton, Joaquı́n Ortega · 2019 · Nucleic Acids Research
- Ribosome-induced tuning of GTP hydrolysis by a translational GTPaseCristina Maracci, Frank Peske, Ev Dannies, Corinna Pohl, Marina V. Rodnina · 2014 · Proceedings of the National Academy of Sciences
- The central role of protein S12 in organizing the structure of the decoding site of the ribosomeHasan DeMi̇rci̇, Leyi Wang, Frank V. Murphy, Eileen L. Murphy, Jennifer F. Carr, Scott C. Blanchard, G. Jogl, Albert E. Dahĺberg, Steven T. Gregory · 2013 · RNA
- Combining Sense and Nonsense Codon Reassignment for Site-Selective Protein Modification with Unnatural Amino AcidsZhenling Cui, Sergey Mureev, Mark E. Polinkovsky, Zakir Tnimov, Zhong Guo, Thomas Durek, Alun Jones, Kirill A. Alexandrov · 2016 · ACS Synthetic Biology
- Chimeric Plantibody Passively Protects Mice against Aerosolized Ricin ChallengeErin K. Sully, Kevin J. Whaley, Natasha Bohorova, Ognian Bohorov, Charles A. Goodman, Do H. Kim, Michael H. Pauly, Jesús Velasco, Ernie Hiatt, Josh Morton et al. · 2014 · Clinical and Vaccine Immunology
- Interaction of Ricin and Shiga Toxins with RibosomesNilgun E. Tumer, Xiao-Ping Li · 2011 · Current topics in microbiology and immunology
- Control of mRNA Translation by Versatile ATP-Driven MachinesMilan Gerovac, Robert Tampé · 2018 · Trends in Biochemical Sciences
- Elongation Factor Ts Directly Facilitates the Formation and Disassembly of the Escherichia coli Elongation Factor Tu·GTP·Aminoacyl-tRNA Ternary ComplexBenjamin J. Burnett, Roger B. Altman, Ryan Ferrao, José Luís Pérez Alejo, Navdep Kaur, Joshua Kanji, Scott C. Blanchard · 2013 · Journal of Biological Chemistry
- Dysregulation of mRNA translation and energy metabolism in cancerMatthew Leibovitch, Ivan Topisirović · 2017 · Advances in Biological Regulation
- Coarse-Grained Structure-Based Model for RNA-Protein Complexes Developed by Fluctuation MatchingNaoto Hori, Shoji Takada · 2012 · Journal of Chemical Theory and Computation
- Quality control of mRNA decoding on the bacterial ribosomeMarina V. Rodnina · 2012 · Advances in protein chemistry and structural biology
- Following movement of domain IV of elongation factor G during ribosomal translocationEnea Salsi, Elie N. Farah, Jillian Dann, Dmitri N. Ermolenko · 2014 · Proceedings of the National Academy of Sciences
- Toxins MazF and MqsR cleave Escherichia coli rRNA precursors at multiple sitesToomas Mets, Markus Lippus, David W. Schryer, Aivar Liiv, Villu Kasari, Anton Paier, Ülo Maiväli, Jaanus Rèmme, Tanel Tenson, Niilo Kaldalu · 2016 · RNA Biology
- The conserved GTPase HflX is a ribosome splitting factor that binds to the E-site of the bacterial ribosomeMackenzie L. Coatham, Harland E. Brandon, Jeffrey J. Fischer, Tobias Schümmer, Hans‐Joachim Wieden · 2016 · Nucleic Acids Research
- Arginine Residues on the Opposite Side of the Active Site Stimulate the Catalysis of Ribosome Depurination by Ricin A Chain by Interacting with the P-protein StalkXiaoping Li, Peter C. Kahn, Jennifer Nielsen Kahn, Przemysław Grela, Nilgun E. Tumer · 2013 · Journal of Biological Chemistry
- Evolutionary tuning impacts the design of bacterial tRNAs for the incorporation of unnatural amino acids by ribosomesOlke C. Uhlenbeck, Jared M. Schrader · 2018 · Current Opinion in Chemical Biology
- Small-Molecule Inhibitors of Ricin and Shiga ToxinsPaul G. Wahome, Jon D. Robertus, Nicholas John Mantis · 2011 · Current topics in microbiology and immunology
- Targeting ricin to the ribosomeKerrie L. May, Qing Yan, Nilgun E. Tumer · 2013 · Toxicon
- Structure of BipA in GTP form bound to the ratcheted ribosomeVeerendra Kumar, Yun Chen, Rya Ero, Tofayel Uddin Ahmed, Jackie Tan, Zhe Li, Andrew See Weng Wong, Shashi Bhushan, Yong‐Gui Gao · 2015 · Proceedings of the National Academy of Sciences
- Comment on “The Mechanism for Activation of GTP Hydrolysis on the Ribosome”Anders Liljas, Måns Ehrenberg, Johan Åqvist · 2011 · Science
- Flipping of the Ribosomal A-Site Adenines Provides a Basis for tRNA SelectionXiancheng Zeng, Jeetender Chugh, Anette Casiano‐Negroni, Hashim M. Al‐Hashimi, Charles L. Brooks · 2014 · Journal of Molecular Biology
- The enigmatic ribosomal stalkAnders Liljas, Suparna Sanyal · 2018 · Quarterly Reviews of Biophysics
- A Master Switch Couples Mg2+-Assisted Catalysis to Domain Motion in B. stearothermophilus Tryptophanyl-tRNA SynthetaseVioletta Weinreb, Li Li, Charles W. Carter · 2012 · Structure
- Structural basis for translation termination by archaeal RF1 and GTP-bound EF1α complexKan Kobayashi, Kazuki Saito, Ryuichiro Ishitani, Koichi Ito, Osamu Nureki · 2012 · Nucleic Acids Research
- Exceptionally large entropy contributions enable the high rates of GTP hydrolysis on the ribosomeJohan Åqvist, Shina Caroline Lynn Kamerlin · 2015 · Scientific Reports
- A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acidsKa-Weng Ieong, Michael Yu. Pavlov, Marek Kwiatkowski, Måns Ehrenberg, Anthony C. Forster · 2014 · RNA
- Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporationMalgorzata Dobosz-Bartoszek, Mark H. Pinkerton, Zbyszek Otwinowski, Srinivas Chakravarthy, Dieter G. Söll, Paul R. Copeland, Miljan Simonović · 2016 · Nature Communications
- The Selenocysteine-specific Elongation Factor Contains a Novel and Multi-functional DomainJonathan González-Flores, Nirupama Gupta, Louise W. DeMong, Paul R. Copeland · 2012 · Journal of Biological Chemistry
- The impact of the stringent response on TRAFAC GTPases and prokaryotic ribosome assembly.Bennison, Daniel J., Irving, Sophie E., Corrigan, Rebecca M. · 2019 · Cells
- Contribution of intersubunit bridges to the energy barrier of ribosomal translocationQi Liu, Kurt L. Fredrick · 2012 · Nucleic Acids Research
- Convergent evolution of AUA decoding in bacteria and archaeaTsutomu Suzuki, Tomoyuki Numata · 2014 · RNA Biology
- Structures of Eukaryotic Ribosomal Stalk Proteins and Its Complex with Trichosanthin, and Their Implications in Recruiting Ribosome-Inactivating Proteins to the RibosomesAndrew Choi, Eddie Wong, Ka-Ming Lee, Kam‐Bo Wong · 2015 · Toxins
- Characterizing and Alleviating Substrate Limitations for Improved in vitro Ribosome ConstructionYi Liu, Brian R. Fritz, Mark Joseph Anderson, Jennifer A. Schoborg, Michael C. Jewett · 2014 · ACS Synthetic Biology
- Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2Etienne Dubiez, Alexey V. Aleksandrov, Christine Lazennec‐Schurdevin, Yves Méchulam, Emmanuelle Schmitt · 2015 · Nucleic Acids Research
- The P 1/ P 2 proteins of the human ribosomal stalk are required for ribosome binding and depurination by ricin in human cellsKerrie L. May, Xiao‐Ping Li, Francisco Martínez‐Azorín, Juan P. G. Ballesta, Przemysław Grela, Marek Tchórzewski, Nilgun E. Tumer · 2012 · FEBS Journal
- Characterization of a new toxin from the entomopathogenic fungus Metarhizium anisopliae: the ribotoxin anisoplinMiriam Olombrada, Pilar Medina, Flor Budia, José G. Gavilanes, Álvaro Martínez‐del‐Pozo, Lucía Garciá‐Ortega · 2016 · Biological Chemistry
- Extensions, Extra Factors, and Extreme Complexity: Ribosomal Structures Provide Insights into Eukaryotic TranslationMelanie Bianca Weisser, Nenad Ban · 2019 · Cold Spring Harbor Perspectives in Biology
- The space between notes: emerging roles for translationally silent ribosomesPatrick R. Smith, Sapna C. Pandit, Sarah Loerch, Zachary T. Campbell · 2022 · Trends in Biochemical Sciences
- The Conformation of a Catalytic Loop Is Central to GTPase Activity on the RibosomeJohan Åqvist, Shina Caroline Lynn Kamerlin · 2014 · Biochemistry
- Multiplication of Ribosomal P-Stalk Proteins Contributes to the Fidelity of TranslationLeszek Wawiórka, Eliza Molestak, Monika Szajwaj, Barbara Michalec‐Wawiórka, Mateusz Mołoń, Lidia Borkiewicz, Przemysław Grela, Aleksandra Boguszewska, Marek Tchórzewski · 2017 · Molecular and Cellular Biology
- Roles of elusive translational GTPases come to light and inform on the process of ribosome biogenesis in bacteriaMichelle R. Gibbs, Kurt L. Fredrick · 2017 · Molecular Microbiology
- Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomesManuel F. Juette, Jordan D. Carelli, Emily J. Rundlet, Alan Brown, Sichen Shao, Angelica Ferguson, Michael R. Wasserman, Mikael Holm, Jack Taunton, Scott C. Blanchard · 2022 · eLife
- Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound stateCrystal E. Fagan, J.A. Dunkle, Tatsuya Maehigashi, Mai N. Dang, Aishwarya Devaraj, Stacey J. Miles, Daoming Qin, Kurt L. Fredrick, Christine M. Dunham · 2013 · Proceedings of the National Academy of Sciences
- High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocationMiglė Kišonaitė, Klemens Wild, Karine Lapouge, Thomas Ruppert, Irmgard Sinning · 2022 · Nature Communications
- RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocketJorge Pedro López-Alonso, Tatsuya Kaminishi, Takeshi Kikuchi, Yuya Hirata, Idoia Iturrioz, Neha Dhimole, Andreas Schedlbauer, Yoichi Hase, Simon Goto, Daisuke Kurita et al. · 2017 · Nucleic Acids Research
- A monovalent cation acts as structural and catalytic cofactor in translational GTPasesBernhard Kuhle, Ralf Ficner · 2014 · The EMBO Journal
- Crystal structure analysis of the translation factor RF3 (release factor 3)Kiyohito Kihira, Yoshihiro Shimizu, Yasuhito Shomura, Naoki Shibata, Masaya Kitamura, Atsushi Nakagawa, Takuya Ueda, Kozo Ochi, Yoshiki Higuchi · 2012 · FEBS Letters
- Role of a ribosomal RNA phosphate oxygen during the EF-G–triggered GTP hydrolysisMiriam Koch, Sara Flür, Christoph Kreutz, Eric Ennifar, Ronald Micura, Norbert Polacek · 2015 · Proceedings of the National Academy of Sciences
- Ribosome engineering to promote new crystal formsM. Selmer, Yong‐Gui Gao, Albert Weixlbaumer, Venki Ramakrishnan · 2012 · Acta Crystallographica Section D Biological Crystallography
- Natural products as drugs and tools for influencing core processes of eukaryotic mRNA translationLuisa D. Burgers, Robert Fürst · 2021 · Pharmacological Research
- Common Mechanism of Activated Catalysis in P-loop Fold Nucleoside Triphosphatases—United in DiversityMaria I. Kozlova, Daria N. Shalaeva, Daria V. Dibrova, Armen Y. Mulkidjanian · 2022 · Biomolecules
- 38 Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndromeAndrew J. Finch, Christine Hilcenko, Nicolas Basse, Lesley F. Drynan, Beatriz Goyenechea, Tobias Menne, Á. González Fernández, Peter J. Simpson, Clive S. D’Santos, Mark Johan Arends et al. · 2011 · Leukemia Research
- SmpB as the handyman of tmRNA during trans-translationBrice Felden, Reynald Gillet · 2011 · RNA Biology
- Human ribosomal P1-P2 heterodimer represents an optimal docking site for ricin A chain with a prominent role for P1 C-terminusPrzemysław Grela, Xiaoping Li, Patrycja Horbowicz‐Drożdżal, Monika Dźwierzyńska, Marek Tchórzewski, Nilgun E. Tumer · 2017 · Scientific Reports
- Single-Molecule Fluorescence Applied to TranslationArjun Prabhakar, Elisabetta Viani Puglisi, Joseph Daniel Puglisi · 2018 · Cold Spring Harbor Perspectives in Biology
- Catalytic promiscuity in Pseudomonas aeruginosa arylsulfatase as an example of chemistry‐driven protein evolutionJinghui Luo, Bert van Loo, Shina Caroline Lynn Kamerlin · 2012 · FEBS Letters
- Close proximity of phosphorylation sites to ligand in the phosphoproteome of the extreme thermophile T hermus thermophilus HB 8Yoshio Takahata, Masao Inoue, Kwang Jin Kim, Yota Iio, Masaaki Miyamoto, Ryoji Masui, Yasushi Ishihama, Seiki Kuramitsu · 2012 · PROTEOMICS
- Elucidating the GTP Hydrolysis Mechanism in FeoB: A Hydrophobic Amino-Acid Substituted GTPaseNeha Vithani, Sahil Batra, Balaji Prakash, Nisanth N. Nair · 2016 · ACS Catalysis
- Challenges and advances in the computational modeling of biological phosphate hydrolysisDušan Petrović, Klaudia Szeler, Shina Caroline Lynn Kamerlin · 2018 · Chemical Communications
- One molecule at a timeMikael Käll · 2012 · Nature Nanotechnology
- Sordarin— An anti‐fungal antibiotic with a unique modus operandiYutian Shao, Eliza Molestak, Weike Su, M. Stankevič, Marek Tchórzewski · 2021 · British Journal of Pharmacology
- Structure of the ciliogenesis-associated CPLANE complexGerasimos Langousis, Simone Cavadini, Niels Boegholm, Esben Lorentzen, Georg Kempf, Patrick Matthias · 2022 · Science Advances
- Recognition of 3′ nucleotide context and stop codon readthrough are determined during mRNA translation elongationNikita Biziaev, Elizaveta Sokolova, Dmitry V. Yanvarev, I. Yu. Toropygin, Alexey V. Shuvalov, Tatiana Egorova, Elena Z. Alkalaeva · 2022 · Journal of Biological Chemistry
- A conserved histidine in switch-II of EF-G moderates release of inorganic phosphateRavi Kiran Koripella, Mikael Holm, Daniel F. A. R. Dourado, Chandra Sekhar Mandava, Samuel Coulbourn Flores, Suparna Sanyal · 2015 · Scientific Reports
- E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound formJesper Johansen, Darius Kavaliauskas, Shawn H. Pfeil, Mickaël Blaise, Barry S. Cooperman, Yale E. Goldman, Søren Thirup, Charlotte Rohde Knudsen · 2018 · Nucleic Acids Research
- Mutational analysis of the ribosome assembly GTPase RbgA provides insight into ribosome interaction and ribosome-stimulated GTPase activationMegha Gulati, Nikhil Jain, Baskaran Anand, Balaji Prakash, Robert A. Britton · 2013 · Nucleic Acids Research
- Conserved Motifs in Different Classes of GTPases Dictate their Specific Modes of CatalysisJohan Åqvist, Shina Caroline Lynn Kamerlin · 2016 · ACS Catalysis
- EF-Tu dynamics during pre-translocation complex formation: EF-Tu·GDP exits the ribosome via two different pathwaysWei Liu, Chunlai Chen, Darius Kavaliauskas, Charlotte Rohde Knudsen, Yale E. Goldman, Barry S. Cooperman · 2015 · Nucleic Acids Research
- Distortion of tRNA upon Near-cognate Codon Recognition on the RibosomeJoerg Mittelstaet, Andrey L. Konevega, Marina V. Rodnina · 2011 · Journal of Biological Chemistry
- Mechanism of activation of elongation factor Tu by ribosome: Catalytic histidine activates GTP by protonationAlexey V. Aleksandrov, Martin J. Field · 2013 · RNA
- The ribotoxin α-sarcin can cleave the sarcin/ricin loop on late 60S pre-ribosomesMiriam Olombrada, Cohue Peña, Olga Rodríguez‐Galán, Purnima Klingauf‐Nerurkar, Daniela Portugal-Calisto, Michaela Oborská‐Oplová, Martin Altvater, José G. Gavilanes, Álvaro Martínez‐del‐Pozo, Jesús de la Cruz et al. · 2020 · Nucleic Acids Research
- Bridging the gap between ribosome structure and biochemistry by mechanistic computationsJohan Åqvist, Christoffer Lind, Johan Sund, Göran Wallin · 2012 · Current Opinion in Structural Biology
- Selenocysteine Insertion Sequence (SECIS)-binding Protein 2 Alters Conformational Dynamics of Residues Involved in tRNA Accommodation in 80 S RibosomesKelvin Caban, Paul R. Copeland · 2012 · Journal of Biological Chemistry
- Response to Comment on “The Mechanism for Activation of GTP Hydrolysis on the Ribosome”R.M. Voorhees, T.M. Schmeing, Ann C. Kelley, Venki Ramakrishnan · 2011 · Science
- The mechanics of ribosomal translocationJohn Achenbach, Knud H. Nierhaus · 2014 · Biochimie
- Revelation of a Catalytic Calcium-Binding Site Elucidates Unusual Metal Dependence of a Human ApyraseDavid W. Rooklin, Min Lu, Yingkai Zhang · 2012 · Journal of the American Chemical Society
- Crystal structure of the full-length bacterial selenocysteine-specific elongation factor SelBYuzuru Itoh, Shun‐ichi Sekine, Shigeyuki Yokoyama · 2015 · Nucleic Acids Research
- Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiationBridget Y. Huang, Israel S. Fernández · 2020 · Proceedings of the National Academy of Sciences
- Frameshifting dynamicsIgnacio Tinoco, Hee‐Kyung Kim, Shannon Yan · 2013 · Biopolymers
- On elongation factor eEFSec, its role and mechanism during selenium incorporation into nascent selenoproteinsMiljan Simonović, Anupama K. Puppala · 2018 · Biochimica et Biophysica Acta (BBA) - General Subjects
- tRNA Dissociation from EF-Tu after GTP Hydrolysis: Primary Steps and Antibiotic InhibitionMalte Warias, Helmut Grubmüller, Lars V. Bock · 2019 · Biophysical Journal
- Examining the promiscuous phosphatase activity of Pseudomonas aeruginosa arylsulfatase: A comparison to analogous phosphatasesJinghui Luo, Bert van Loo, Shina Caroline Lynn Kamerlin · 2011 · Proteins Structure Function and Bioinformatics
- Stability and Function at High Temperature. What Makes a Thermophilic GTPase Different from Its Mesophilic HomologueMarina Katava, Maria Kalimeri, Guillaume Stirnemann, Fabio Sterpone · 2016 · The Journal of Physical Chemistry B
- Maintaining mitochondrial ribosome function: The role of ribosome rescue and recycling factorsFranziska Nadler, Elena Lavdovskaia, Ricarda Richter‐Dennerlein · 2021 · RNA Biology
- A Sixty-Year Research and Development of Trichosanthin, a Ribosome-Inactivating ProteinJiaqi Lü, Kam‐Bo Wong, Pang‐Chui Shaw · 2022 · Toxins
- Role of aIF5B in archaeal translation initiationRamy Kazan, Gabrielle Bourgeois, Christine Lazennec‐Schurdevin, Éric Larquet, Yves Méchulam, Pierre‐Damien Coureux, Emmanuelle Schmitt · 2022 · Nucleic Acids Research
- Structural Basis Unifying Diverse GTP Hydrolysis MechanismsBaskaran Anand, Soneya Majumdar, Balaji Prakash · 2013 · Biochemistry
- The effect of magnesium ions on triphosphate hydrolysisAlexandre Hernandes Barrozo, David Blaha-Nelson, Nicholas H. Williams, Shina Caroline Lynn Kamerlin · 2017 · Pure and Applied Chemistry
- Divalent ions tune the kinetics of a bacterial GTPase center rRNA folding transition from secondary to tertiary structureRobb S. Welty, Suzette A. Pabit, Andrea M. Katz, George D. Calvey, Lois Pollack, Kathleen B. Hall · 2018 · RNA
- Functional analysis of the uL11 protein impact on translational machineryLeszek Wawiórka, Eliza Molestak, Monika Szajwaj, Barbara Michalec‐Wawiórka, Aleksandra Boguszewska, Lidia Borkiewicz, Vladyslava Liudkovska, Joanna Kufel, Marek Tchórzewski · 2016 · Cell Cycle
- Mechanism of Translation Termination: RF1 Dissociation Follows Dissociation of RF3 from the RibosomeXinying Shi, Simpson Joseph · 2016 · Biochemistry
- EF-Tu and EF-G are activated by allosteric effectsDibyendu Mondal, Arieh Warshel · 2018 · Proceedings of the National Academy of Sciences
- Translation initiation without IF2-dependent GTP hydrolysisAttilio Fabbretti, Letizia Brandi, Pohl Milón, Roberto Spurio, Cynthia L. Pon, Claudio Orlando Gualerzi · 2012 · Nucleic Acids Research
- Similarity and diversity of translational GTPase factors EF-G, EF4, and BipA: From structure to functionRya Ero, Veerendra Kumar, Yun Chen, Yong‐Gui Gao · 2016 · RNA Biology
- Interaction of tRNA with Eukaryotic RibosomeD. M. Graifer, Galina G. Karpova · 2015 · International Journal of Molecular Sciences