CoChat
Sign Up
Cited by 233melanin and skin pigmentationDevelopmental Biology and Gene RegulationHair Growth and Disorders

The Developmental Role of Agouti in Color Pattern Evolution

Open access
Manceau, Marie, Domingues, Vera S., Mallarino, Ricardo, Hoekstra, Hopi E.·2011·Science
DOI 10.1126/science.1200684
Open this paper in CoChat — free account

Abstract

A regulatory mutation affecting expression of the Agouti gene shows color-specific selection in beach mice.

Integrity signals

Registry

Crossref · 10.1126/science.1200684

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Asip1 and the orthologous protein of mammals, Asip, are Melanocortin-1 receptor (Mc1r) antagonists and their ventral expression inhibits differentiation of melanophores and melanocytes, respectively, resulting in light bellies.

    “Asip1 and the orthologous protein of mammals, Asip, are Melanocortin-1 receptor (Mc1r) antagonists and their ventral expression inhibits differentiation of melanophores and melanocytes, respectively, resulting in light bellies (24–27).”

    From Agouti and BMP signaling drive a naturally occurring fate conversion of melanophores to leucophores in zebrafish (2025) · cites this paper as [25]

Cited by

Sorted by citations

Authors
Manceau, M., Domingues, V. S., Mallarino, R., & Hoekstra, H. E.
Affiliations
Harvard University (US)
Corresponding author
Hoekstra, Hopi E.
ORCID
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2011-02-25
Volume
331
Issue
6020
Pages
1062-1065
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.1200684
OpenAlex
W2106981394
Cited by
233
References
0
Citations by year
2026: 5 · 2025: 10 · 2024: 13 · 2023: 8 · 2022: 9 · 2021: 7 · 2020: 13 · 2019: 20 · 2018: 45 · 2017: 18 · 2016: 16 · 2015: 8 · 2014: 16 · 2013: 21 · 2012: 15
FWCI
8.80
Type
journal article
Language
en
Open access
Licence
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
  • Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
  • HAL (submittedVersion)
Funders
National Science Foundation (DEB-0919190)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
  • Health Sciences › Medicine › Urology › Hair Growth and Disorders
Keywords
agouti, color pattern evolution, Peromyscus, melanocyte differentiation, natural selection, adaptive coloration
MeSH terms
Epidermal Cells, Alleles, Animals, Cell Differentiation, Embryo, Mammalian, Epidermis, Biological Evolution, Female, Fetus, Hair Color, Male, Melanocytes, Mutation, Peromyscus, Skin, Gene Expression, Gene Expression Regulation, Developmental, Hair Follicle, Body Patterning, Dermis, Cell Proliferation, Agouti Signaling Protein

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review