The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Opening and Closing of the Bacterial RNA Polymerase Clamp
Open accessAbstract
Clamping Down: Crystal structures of RNA polymerase show that a “clamp” region which surrounds the DNA binding site can adopt conformations ranging from a closed to an open state. Chakraborty et al. (p. 591 ) used single-molecule fluorescence energy transfer experiments to detect the clamp's conformational changes in solution during the transcription cycle. The results support a model in which a clamp opening allows DNA to be loaded into the active-center cleft and unwound. Direct interactions with DNA likely trigger clamp closure upon formation of a catalytically competent transcription initiation complex.
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Cites
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
Cramer, P., Bushnell, D. A., & Kornberg, R. D. (2001) · Science · doi:10.1126/science.1059493 · Cited by 1,247
Cited by
Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins
Lang, K., & Chin, J. W. (2014) · Chemical Reviews · doi:10.1021/cr400355w · Cited by 1,035
Mechanism of Transcriptional Bursting in Bacteria
Chong, S., Chen, C., Ge, H., & Xie, X. S. (2014) · Cell · doi:10.1016/j.cell.2014.05.038 · Cited by 428
Mechanisms of Bacterial Transcription Termination: All Good Things Must End
Ray-Soni, A., Bellecourt, M. J., & Landick, R. (2016) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060815-014844 · Cited by 351
Structural visualization of key steps in human transcription initiation
He, Y., Fang, J., Taatjes, D. J., & Nogales, E. (2013) · Nature · doi:10.1038/nature11991 · Cited by 282
Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase
Fraser, A., Sokolova, M. L., Drobysheva, A. V., Gordeeva, J. V., Borukhov, S., Jumper, J., Severinov, K. V., & Leiman, P. G. (2022) · Nature Communications · doi:10.1038/s41467-022-31214-6 · Cited by 7
Metadata
- Authors
- Chakraborty, A., Wang, D., Ebright, Y. W., Korlann, Y., Kortkhonjia, E., Kim, T., Chowdhury, S., Wigneshweraraj, S., Irschik, H., Jansen, R., Nixon, B. T., Knight, J., Weiss, S., & Ebright, R. H.
- Venue
- Science
- Published
- 2012-08-03
- Volume
- 337
- Issue
- 6094
- Pages
- 591-595
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2054901066
- Cited by
- 230
- References
- 1
- FWCI
- 12.93
- Type
- journal article
- Language
- en
- Open access
- green
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- Chakraborty, A., Wang, D., Ebright, Y. W., Korlann, Y., Kortkhonjia, E., Kim, T., Chowdhury, S., Wigneshweraraj, S., Irschik, H., Jansen, R., Nixon, B. T., Knight, J., Weiss, S., & Ebright, R. H. (2012). Opening and Closing of the Bacterial RNA Polymerase Clamp. Science. https://doi.org/10.1126/science.1218716
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
