The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
A Dynamical-Systems View of Stem Cell Biology
Abstract
During development, cells undergo a unidirectional course of differentiation that progressively decreases the number of cell types they can potentially become. Stem cells, however, keep their potential to both proliferate and differentiate. A very important issue then is to understand the characteristics that distinguish stem cells from other cell types and allow them to conduct stable proliferation and differentiation. Here, we review relevant dynamical-systems approaches to describe the state transition between stem and differentiated cells, with an emphasis on fluctuating and oscillatory gene expression levels, as these represent the specific properties of stem cells. Relevance between recent experimental results and dynamical-systems descriptions of stem cell differentiation is also discussed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Origins of Order: Self-Organization and Selection in Evolution
Kauffman, S. A. (1993) · doi:10.1093/oso/9780195079517.001.0001 · Cited by 7,855
Cell Fates as High-Dimensional Attractor States of a Complex Gene Regulatory Network
Huang, S., Eichler, G., Bar-Yam, Y., & Ingber, D. E. (2005) · Physical Review Letters · doi:10.1103/physrevlett.94.128701 · Cited by 775
Biological Physics of the Developing Embryo
Forgacs, G., & Newman, S. A. (2005) · doi:10.1017/cbo9780511755576 · Cited by 339
Inferring rules of lineage commitment in haematopoiesis
Pina, C., Fugazza, C., Tipping, A. J., Brown, J., Soneji, S., Teles, J., Peterson, C., & Enver, T. (2012) · Nature Cell Biology · doi:10.1038/ncb2442 · Cited by 162
Cited by
Lloyd-Price, J., Abu-Ali, G., & Huttenhower, C. (2016) · Genome Medicine · doi:10.1186/s13073-016-0307-y · Cited by 1,891
‘Big data’, Hadoop and cloud computing in genomics
O’Driscoll, A., Daugelaite, J., & Sleator, R. D. (2013) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2013.07.001 · Cited by 431
Glioblastoma Stem Cells: Driving Resilience through Chaos
Prager, B. C., Bhargava, S., Mahadev, V., Hubert, C. G., & Rich, J. N. (2020) · Trends in Cancer · doi:10.1016/j.trecan.2020.01.009 · Cited by 401
Cell Fate Decision as High-Dimensional Critical State Transition
Mojtahedi, M., Skupin, A., Zhou, J., Castaño, I. G., Leong-Quong, R. Y. Y., Chang, H., Trachana, K., Giuliani, A., & Huang, S. (2016) · PLOS Biology · doi:10.1371/journal.pbio.2000640 · Cited by 350
Data based identification and prediction of nonlinear and complex dynamical systems
Wang, W.-X., Lai, Y.-C., & Grebogi, C. (2016) · Physics Reports · doi:10.1016/j.physrep.2016.06.004 · Cited by 299
Metadata
- Authors
- Furusawa, C., & Kaneko, K.
- Venue
- Science
- Published
- 2012-10-12
- Volume
- 338
- Issue
- 6104
- Pages
- 215-217
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1978217382
- Cited by
- 194
- References
- 4
- FWCI
- 6.51
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A Dynamical-Systems View of Stem Cell Biology. https://app.cochat.ai/papers/10.1126/science.1224311
- The paper
- Furusawa, C., & Kaneko, K. (2012). A Dynamical-Systems View of Stem Cell Biology. Science. https://doi.org/10.1126/science.1224311
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
