The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Active DNA Demethylation in Plant Companion Cells Reinforces Transposon Methylation in Gametes
Open accessAbstract
Intergenerational Transposable Shutdown: Transposable elements (TEs) are a potential threat, especially to the germline genome. In many eukaryotes, TEs are shut down by DNA methylation and/or small-RNA–mediated silencing. Therefore, it seems counterintuitive that results obtained by Ibarra et al. (p. 1360 ) on Arabidopsis showed that in the cells of this plant's sexual apparatus, many small TEs are demethylated by DEMETER (DME) DNA glycosylase and become activated. But it turns out that activation of the TEs triggers the formation of small-interfering RNAs, which in these experiments were seen to travel from the surrounding cells to the egg. Thus, activation of TEs in the companion cells “immunizes” the gametes via the interfering RNAs that shutdown the TEs in the gametes permanently.
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Cites
Early flower development in Arabidopsis.
Smyth, D. R., Bowman, J. L., & Meyerowitz, E. M. (1990) · The Plant Cell · doi:10.1105/tpc.2.8.755 · Cited by 2,155
Bernatavichute, Y. V., Zhang, X., Cokus, S., Pellegrini, M., & Jacobsen, S. E. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003156 · Cited by 333
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Deniz, Ö., Frost, J. M., & Branco, M. R. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-019-0106-6 · Cited by 486
DNA methylation dynamics during early plant life
Bouyer, D., Kramdi, A., Kassam, M., Heese, M., Schnittger, A., Roudier, F., & Colot, V. (2017) · Genome Biology · doi:10.1186/s13059-017-1313-0 · Cited by 239
Dynamics of dna methylation and its functions in plant growth and development
Kumar, S., & Mohapatra, T. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.596236 · Cited by 227
EPIGENETIC VARIATION IN ASEXUALLY REPRODUCING ORGANISMS: SPECIAL SECTION
Verhoeven, K. J. F., & Preite, V. (2014) · Evolution · doi:10.1111/evo.12320 · Cited by 216
Metadata
- Authors
- Ibarra, C. A., Feng, X., Schoft, V. K., Hsieh, T.-F., Uzawa, R., Rodrigues, J. A., Zemach, A., Chumak, N., Machlicova, A., Nishimura, T., Rojas, D., Fischer, R. L., Tamaru, H., & Zilberman, D.
- Venue
- Science
- Published
- 2012-09-14
- Volume
- 337
- Issue
- 6100
- Pages
- 1360-1364
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2018249152
- Cited by
- 498
- References
- 2
- FWCI
- 12.90
- Type
- journal article
- Language
- en
- Open access
- green
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- Ibarra, C. A., Feng, X., Schoft, V. K., Hsieh, T.-F., Uzawa, R., Rodrigues, J. A., Zemach, A., Chumak, N., Machlicova, A., Nishimura, T., Rojas, D., Fischer, R. L., Tamaru, H., & Zilberman, D. (2012). Active DNA Demethylation in Plant Companion Cells Reinforces Transposon Methylation in Gametes. Science. https://doi.org/10.1126/science.1224839
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