The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation
Abstract
Limiting Tumor Initiation: What is the competitive advantage of cells with frequently occurring mutations during tumor development? Vermeulen et al. (p. 995 ; see the Perspective by Bozic and Nowak ) quantified the advantages of Apc -loss, Kras activation, and P53 mutation during tumor initiation in the mouse intestine. The mutations conferred only a limited clonal advantage. Indeed, many mutated stem cells were stochastically replaced by wild-type stem cells, helping to limit tumor initiation.
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ggplot2: Elegant Graphics for Data Analysis
Wickham, H. (2009) · doi:10.1007/978-0-387-98141-3 · Cited by 14,447
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
Madisen, L., Zwingman, T. A., Sunkin, S. M., Oh, S. W., Zariwala, H. A., Gu, H., Ng, L. L., Palmiter, R. D., Hawrylycz, M. J., Jones, A. R., et al. (2010) · Nature Neuroscience · doi:10.1038/nn.2467 · Cited by 6,907
Nowell, P. C. (1976) · Science · doi:10.1126/science.959840 · Cited by 6,471
Identification of stem cells in small intestine and colon by marker gene Lgr5
Barker, N., van Es, J. H., Kuipers, J., Kujala, P., van den Born, M., Cozijnsen, M., Haegebarth, A., Korving, J., Begthel, H., Peters, P. J., et al. (2007) · Nature · doi:10.1038/nature06196 · Cited by 5,687
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
Olive, K. P., Tuveson, D. A., Ruhe, Z. C., Yin, B., Willis, N. A., Bronson, R. T., Crowley, D., & Jacks, T. (2004) · Cell · doi:10.1016/j.cell.2004.11.004 · Cited by 1,308
Intestinal label-retaining cells are secretory precursors expressing Lgr5
Buczacki, S. J. A., Zecchini, H. I., Nicholson, A. M., Russell, R., Vermeulen, L., Kemp, R., & Winton, D. J. (2013) · Nature · doi:10.1038/nature11965 · Cited by 761
Self-citationKozar, S., Morrissey, E., Nicholson, A. M., van der Heijden, M., Zecchini, H. I., Kemp, R., Tavaré, S., Vermeulen, L., & Winton, D. J. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2013.08.001 · Cited by 214
Self-citationUsing the R Package crlmm for Genotyping and Copy Number Estimation
Scharpf, R. B., Irizarry, R. A., Ritchie, M. E., Carvalho, B., & Ruczinski, I. (2011) · Journal of Statistical Software · doi:10.18637/jss.v040.i12 · Cited by 52
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From tumour heterogeneity to advances in precision treatment of colorectal cancer
Punt, C. J. A., Koopman, M., & Vermeulen, L. (2017) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2016.171 · Cited by 654
Self-citationTetteh, P. W., Basak, O., Farin, H. F., Wiebrands, K., Kretzschmar, K., Begthel, H., van den Born, M., Korving, J., de Sauvage, F., van Es, J. H., et al. (2016) · Cell stem cell · doi:10.1016/j.stem.2016.01.001 · Cited by 575
Tumor Organoids as a Pre-clinical Cancer Model for Drug Discovery
Weeber, F., Ooft, S. N., Dijkstra, K. K., & Voest, E. E. (2017) · Cell Chemical Biology · doi:10.1016/j.chembiol.2017.06.012 · Cited by 486
Tumor initiation and early tumorigenesis: molecular mechanisms and interventional targets
Zhang, S., Xiao, X., Yi, Y., Wang, X., Zhu, L., Shen, Y., Lin, D., & Wu, C. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01848-7 · Cited by 399
Metadata
- Authors
- Vermeulen, L., Morrissey, E., van der Heijden, M., Nicholson, A. M., Sottoriva, A., Buczacki, S., Kemp, R., Tavaré, S., & Winton, D. J.
- Venue
- Science
- Published
- 2013-11-22
- Volume
- 342
- Issue
- 6161
- Pages
- 995-998
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1968969468
- Cited by
- 397
- References
- 8
- FWCI
- 16.76
- Type
- journal article
- Language
- en
- Open access
- closed
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- Vermeulen, L., Morrissey, E., van der Heijden, M., Nicholson, A. M., Sottoriva, A., Buczacki, S., Kemp, R., Tavaré, S., & Winton, D. J. (2013). Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation. Science. https://doi.org/10.1126/science.1243148
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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