The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients
Abstract
How do fingers know where to grow?: Most researchers today believe that each finger forms because of its unique position within the early limb bud. However, 30 years ago, developmental biologists proposed that the arrangement of fingers followed the Turing pattern, a self-organizing process during early embryo development. Raspopovic et al. provide evidence to support a Turing mechanism (see the Perspective by Zuniga and Zeller). They reveal that Bmp and Wnt signaling pathways, together with the gene Sox9, form a Turing network. The authors used this network to generate a computer model capable of accurately reproducing the patterns that cells follow as the embryo grows fingers. Science , this issue p. 566 ; see also p. 516
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Smyth, G. K. (2004) · Statistical Applications in Genetics and Molecular Biology · doi:10.2202/1544-6115.1027 · Cited by 11,829
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A comparison of background correction methods for two-colour microarrays
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The chemical basis of morphogenesis
Turing, A. M. (1990) · Bulletin of Mathematical Biology · doi:10.1007/bf02459572 · Cited by 434
Cited by
Positional Information and Pattern Formation
Wolpert, L. (2016) · Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2015.11.008 · Cited by 649
Hierarchical patterning modes orchestrate hair follicle morphogenesis
Glover, J. D., Wells, K. L., Matthäus, F., Painter, K. J., Ho, W., Riddell, J., Johansson, J. A., Ford, M. J., Jahoda, C. A. B., Klika, V., et al. (2017) · PLOS Biology · doi:10.1371/journal.pbio.2002117 · Cited by 155
Agent-based modeling of morphogenetic systems: advantages and challenges.
Glen, C. M., Kemp, M. L., & Voit, E. O. (2019) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1006577 · Cited by 116
The road to synthetic multicellularity
Solé, R., Ollé-Vila, A., Vidiella, B., Duran-Nebreda, S., & Conde-Pueyo, N. (2018) · Current Opinion in Systems Biology · doi:10.1016/j.coisb.2017.11.007 · Cited by 19
Perspectives on the mathematics of biological patterning and morphogenesis
Garikipati, K. (2017) · Journal of the Mechanics and Physics of Solids · doi:10.1016/j.jmps.2016.11.013 · Cited by 28
Metadata
- Authors
- Raspopovic, J., Marcon, L., Russo, L., & Sharpe, J.
- Venue
- Science
- Published
- 2014-08
- Volume
- 345
- Issue
- 6196
- Pages
- 566-570
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2003095799
- Cited by
- 500
- References
- 5
- FWCI
- 14.60
- Type
- journal article
- Language
- en
- Open access
- closed
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