The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication
Open accessAbstract
Rabbits softly swept to domestication: When people domesticate animals, they select for tameness and tolerance of humans. What else do they look for? To identify the selective pressures that led to rabbit domestication, Carneiro et al. sequenced a domestic rabbit genome and compared it to that of its wild brethren (see the Perspective by Lohmueller). Domestication did not involve a single gene changing, but rather many gene alleles changing in frequency between tame and domestic rabbits, known as a soft selective sweep. Many of these alleles have changes that may affect brain development, supporting the idea that tameness involves changes at multiple loci. Science , this issue p. 1074 ; see also p. 1000
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Recent genomic studies (Carneiro et al. 2014; Pendleton et al. 2018; Wang et al. 2018) have found evidence of selection at a few handfuls of genes that have molecular functions associated with the neural crest, but that in itself is not good evidence that neural crest cell proliferation and migration are underlying the domestication syndrome.”
From The neural crest cell hypothesis: no unified explanation for domestication (2021) · cites this paper as Carneiro et al. 2014
Experimental — accuracy not yet measuredIn the citing paper
“These results are in line with claims in other studies on domestication [49, 123–125], where categories like ‘neurological process’ frequently stand out strongly in gene ontology category enrichment analyses.”
From Self-domestication in Homo sapiens: Insights from comparative genomics (2017) · cites this paper as [125]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Basic local alignment search tool
Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990) · Journal of Molecular Biology · doi:10.1006/jmbi.1990.9999 · Cited by 98,669
The Sequence Alignment/Map format and SAMtools
Li, H., Handsaker, B., Wysoker, A., Fennell, T., Ruan, J., Homer, N., Marth, G., Abecasis, G., Durbin, R., & 1000 Genome Project Data Processing Subgroup (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp352 · Cited by 62,041
Fast and accurate short read alignment with Burrows-Wheeler transform
Li, H., & Durbin, R. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp324 · Cited by 58,607
Takahashi, K., & Yamanaka, S. (2006) · Cell · doi:10.1016/j.cell.2006.07.024 · Cited by 26,673
Full-length transcriptome assembly from RNA-Seq data without a reference genome
Grabherr, M. G., Haas, B. J., Yassour, M., Levin, J. Z., Thompson, D. A., Amit, I., Adiconis, X., Fan, L., Raychowdhury, R., Zeng, Q., et al. (2011) · Nature Biotechnology · doi:10.1038/nbt.1883 · Cited by 21,201
Self-citationESTIMATING F -STATISTICS FOR THE ANALYSIS OF POPULATION STRUCTURE
Weir, B. S., & Cockerham, C. C. (1984) · Evolution · doi:10.1111/j.1558-5646.1984.tb05657.x · Cited by 18,909
Molecular Evolutionary Genetics
Nei, M. (1987) · Columbia University Press eBooks · doi:10.7312/nei-92038 · Cited by 16,583
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
Wang, K., Li, M., & Hakonarson, H. H. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq603 · Cited by 14,724
A method and server for predicting damaging missense mutations.
Adzhubei, I. A., Schmidt, S., Peshkin, L., Ramensky, V. E., Gerasimova, A., Bork, P., Kondrashov, A. S., & Sunyaev, S. R. (2010) · Nature Methods · doi:10.1038/nmeth0410-248 · Cited by 13,194
Fast and accurate long-read alignment with Burrows-Wheeler transform.
Li, H., & Durbin, R. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btp698 · Cited by 12,063
Flagged first, then by citations
Research works printed but not linked: 2
- R. C. Soriguer “El conejo: Papel ecológico y estrategia de vida en los ecosistemas mediterráneos ” in XV Congreso Internacional de Fauna Cinegética y Silvestre (Estacion Biologica De Donana Federacion Espanola de Caza Trujillo Spain 1983) pp. 517–542.
- 10.1016/S0022-2836(05)80360-2 · DOI · Paper page
Cited by
Sorted by citations
Items 401–414 of 414
European Rabbit Oryctolagus cuniculus (Linnaeus, 1758)
López, L. I., & Mora, J. M. (2026) · Handbook of the Mammals of Middle and South America. · doi:10.1007/978-3-031-31564-0_32-1
Hubert, J.-N. (2018) · theses.fr (ABES) · doi:10.70675/d3180991zb31fz4017z9085zfac23159b0ae
Seixas, F. (2017) · theses.fr (ABES) · doi:10.70675/979b8521z416ez4ee9z84f5z361713d7ff2f · Cited by 1
Les méthyltransférases des Mononegavirales, une cible antivirale attractive
Valle, C. (2020) · theses.fr (ABES) · doi:10.70675/dd457ab8z171az4e41z97edze8a6d8359e8a
Using genomic tools to understand species differentiation and admixture in hares and mice
Marques, J. P. (2022) · theses.fr (ABES) · doi:10.70675/4a9cb331z69c9z4867z8dbezfa019b800e6b
Hybridization with wild individuals fuels reindeer feralization
Cerca, J., Ravinet, M., Flagstad, Ø., Rolandsen, C. M., Strand, O., Tørresen, O. K., Jakobsen, K. S., & Mysterud, A. (2026) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2026.1226
European Rabbit Oryctolagus cuniculus (Linnaeus, 1758)
López, L. I., & Mora, J. M. (2026) · Handbook of the Mammals of Middle and South America. · doi:10.1007/978-3-032-10769-5_32
Liu, H. (2026) · Research Square · doi:10.21203/rs.3.rs-10863387/v1
Hu, L., Wang, Y.-M., Xie, J., Gu, L., Si, S., Liu, Z.-X., Long, L., Yin, T., Esmailizadeh, A., Wu, F., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2602503123
Genome-wide host-associated population structure of Sarcoptes scabiei: One Health implications
Fang, F., Korhonen, P. K., Huang, S., Moroni, B., Rossi, L., Min, A. R. M., Hou, Z., Colella, V., Liu, Q., Guillot, J., et al. (2026) · Science in One Health · doi:10.1016/j.soh.2026.100168
Applications of Comparative Genomics in Evolutionary Biology
徐, 玉. (2026) · Bioprocess · doi:10.12677/bp.2026.163013
Hecht, E. E., & Barton, S. A. (2026) · Springer eBooks · doi:10.1007/978-3-032-31515-1_9
Metadata
- Authors
- Carneiro, M., Rubin, C.-J., Di Palma, F., Albert, F. W., Alföldi, J., Barrio, A. M., Pielberg, G., Rafati, N., Sayyab, S., Turner-Maier, J., Younis, S., Afonso, S., Aken, B., Alves, J. M., Barrell, D., Bolet, G., Boucher, S., Burbano, H. A., Campos, R., Chang, J. L., Duranthon, V., Fontanesi, L., Garreau, H., Heiman, D., Johnson, J., Mage, R. G., Peng, Z., Queney, G., Rogel-Gaillard, C., Ruffier, M., Searle, S., Villafuerte, R., Xiong, A., Young, S., Forsberg-Nilsson, K., Good, J. M., Lander, E. S., Ferrand, N., Lindblad-Toh, K., & Andersson, L.
- Affiliations
- Universidade do Porto (PT)
- Uppsala University (SE)
- Broad Institute of Harvard and Massachusetts Institute of Technology, 7 Cambridge Center, Cambridge, MA 02142, USA.
- Max Planck Institute for Evolutionary Anthropology (DE)
- Broad Institute (US)
- Science for Life Laboratory Uppsala, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
- Swedish University of Agricultural Sciences (SE)
- Ain Shams University (EG)
- European Bioinformatics Institute (GB)
- Institut National de la Recherche Agronomique (INRA), UMR1388 Génétique, Physiologie et Systèmes d’Elevage, F-31326 Castanet-Tolosan, France.
- Labovet Conseil, BP539, 85505 Les Herbiers Cedex, France.
- INRA, UMR1198 Biologie du Développement et Reproduction, F-78350 Jouy-en-Josas, France.
- University of Bologna (IT)
- Génétique Physiologie et Systèmes d'Elevage (FR)
- National Institutes of Health (US)
- Lawrence Berkeley National Laboratory (US)
- ANTAGENE, Animal Genomics Laboratory, Lyon, France.
- Génétique Animale et Biologie Intégrative (FR)
- Wellcome Sanger Institute (GB)
- Consejo Superior de Investigaciones Científicas (ES)
- Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
- ORCID
- Carneiro, Miguel
- Rubin, Carl-Johan
- Albert, Frank W.
- Alföldi, Jessica
- Pielberg, Gerli
- Rafati, Nima
- Sayyab, Shumaila
- Turner-Maier, Jason
- Younis, Shady
- Afonso, Sandra
- Aken, Bronwen
- Alves, Joel M.
- Barrell, Daniel
- Burbano, Hernán A.
- Campos, Rita
- Fontanesi, Luca
- Garreau, Hervé
- Heiman, David
- Johnson, Jeremy
- Peng, Ze
- Queney, Guillaume
- Rogel-Gaillard, Claire
- Ruffier, Magali
- Villafuerte, Rafael
- Xiong, Anqi
- Young, Sarah
- Good, Jeffrey M.
- Lander, Eric S.
- Ferrand, Nuno
- Andersson, Leif
- Venue
- Science
- Published
- 2014-08-29
- Volume
- 345
- Issue
- 6200
- Pages
- 1074-1079
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- PMC
- PMC5421586
- OpenAlex
- W2132261072
- Cited by
- 404
- References
- 63
- Citations by year
- 2026: 16 · 2025: 21 · 2024: 22 · 2023: 22 · 2022: 36 · 2021: 53 · 2020: 44 · 2019: 41 · 2018: 47 · 2017: 38 · 2016: 37 · 2015: 23 · 2014: 4
- FWCI
- 22.33
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- DSpace@MIT (Massachusetts Institute of Technology) (submittedVersion)
- HAL (submittedVersion, other-oa)
- Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
- Max Planck Digital Library (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- UEA Digital Repository (University of East Anglia) (submittedVersion)
- Funders
- National Science Foundation (WT098051, 0754461)
- Wellcome Trust (095908, WT095908, WT 098051)
- European Molecular Biology Laboratory
- Broad Institute
- Ministério da Ciência, Tecnologia e Ensino Superior
- Science for Life Laboratory
- National Institutes of Health (HG003067)
- Biotechnology and Biological Sciences Research Council (BBS/E/T/000PR5885, BBS/E/T/000PR6193)
- Fundação para a Ciência e a Tecnologia (COMPETE, SFRH/BPD/64365/2009, PTDC/BIA-EVF/115069/2009, 2007/2013, /2009)
- European Regional Development Fund (COMPETE, 2007 – 2013)
- National Human Genome Research Institute (U54HG003067, HG003067)
- National Institute of Allergy and Infectious Diseases
- Office of International Science and Engineering
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and phenotypic traits in livestock
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Human-Animal Interaction Studies
- Keywords
- selective sweeps, single nucleotide polymorphisms, brain development genes, allele frequency change, reference genome
- MeSH terms
- Animals, Animals, Domestic, Animals, Wild, Base Sequence, Behavior, Animal, Breeding, Gene Frequency, Molecular Sequence Data, Phenotype, Rabbits, Selection, Genetic, Genome, Sequence Analysis, DNA, Evolution, Molecular, Polymorphism, Single Nucleotide, Genetic Loci
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
