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Placebo Effect in the Rat
Abstract
Scopolamine hydrobromide disrupts the learned behavior of rats in a predictable manner. Physiological saline mimics to some extent the effect of the drug when the two substances are alternately administered in a series of injections. This placebo effect appears to be an instance of simple Pavlovian conditioning.
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Citations
Cited by
Amanzio, M., & Benedetti, F. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-01-00484.1999 · Cited by 899
Response expectancy as a determinant of experience and behavior.
Kirsch, I. (1985) · American Psychologist · doi:10.1037/0003-066x.40.11.1189 · Cited by 801
Benedetti, F., Pollo, A., Lopiano, L., Lanotte, M., Vighetti, S., & Rainero, I. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-10-04315.2003 · Cited by 788
The Placebo Effect: Dissolving the Expectancy Versus Conditioning Debate.
Stewart-Williams, S., & Podd, J. (2004) · Psychological Bulletin · doi:10.1037/0033-2909.130.2.324 · Cited by 664
Placebo and the New Physiology of the Doctor-Patient Relationship
Benedetti, F. (2013) · Physiological Reviews · doi:10.1152/physrev.00043.2012 · Cited by 492
Metadata
- Authors
- Herrnstein, R. J.
- Venue
- Science
- Published
- 1962-11-09
- Volume
- 138
- Issue
- 3541
- Pages
- 677-678
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2081518255
- Cited by
- 190
- References
- 0
- FWCI
- 2.23
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Placebo Effect in the Rat. https://app.cochat.ai/papers/10.1126/science.138.3541.677
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- Herrnstein, R. J. (1962). Placebo Effect in the Rat. Science. https://doi.org/10.1126/science.138.3541.677
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.