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Glucose-6-Phosphate Dehydrogenase Mosaicism: Utilization as a Cell Marker in the Study of Leiomyomas
Abstract
The sex-linked electrophoretic variants A and B of glucose-6-phosphate dehydrogenase were studied in 86 samples of myometrium and 27 leiomyomas from five heterozygous women. All but one sample of myometrium had both A and B bands in equal or nearly equal amounts. In contrast to this, all of the leiomyomas had either an A band or a B band. Both A and B tumors were found in all uteri. These findings are consistent with the hypothesis that these tumors arose from single cells.
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Citations
Cited by
Nowell, P. C. (1976) · Science · doi:10.1126/science.959840 · Cited by 6,471
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Ross, R., & Glomset, J. A. (1976) · New England Journal of Medicine · doi:10.1056/nejm197608192950805 · Cited by 1,163
Bulun, S. E. (2013) · New England Journal of Medicine · doi:10.1056/nejmra1209993 · Cited by 703
Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age
Busque, L., Mio, R., Mattioli, J., Brais, E., Blais, N., Lalonde, Y., Maragh, M., & Gilliland, D. (1996) · Blood · doi:10.1182/blood.v88.1.59.59 · Cited by 543
Paroxysmal Nocturnal Hemoglobinuria: Evidence for Monoclonal Origin of Abnormal Red Cells
ONI, S. B., OSUNKOYA, B. O., & LUZZATTO, L. (1970) · Blood · doi:10.1182/blood.v36.2.145.145 · Cited by 275
Metadata
- Authors
- Linder, D., & Gartler, S. M.
- Venue
- Science
- Published
- 1965-10
- Volume
- 150
- Issue
- 3692
- Pages
- 67-69
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2076173229
- Cited by
- 395
- References
- 0
- FWCI
- 39.36
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Glucose-6-Phosphate Dehydrogenase Mosaicism: Utilization as a Cell Marker in the Study of Leiomyomas. https://app.cochat.ai/papers/10.1126/science.150.3692.67
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- Linder, D., & Gartler, S. M. (1965). Glucose-6-Phosphate Dehydrogenase Mosaicism: Utilization as a Cell Marker in the Study of Leiomyomas. Science. https://doi.org/10.1126/science.150.3692.67
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
