The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Interaction Between Human Cyclin A and Adenovirus E1A-Associated p107 Protein
Abstract
The products of the adenovirus early region 1A (E1A) gene are potent oncoproteins when tested in standard transformation and immortalization assays. Many of the changes induced by E1A may be due to its interaction with cellular proteins. Four of these cellular proteins are the retinoblastoma protein (pRB), p107, cyclin A, and p33 cdk2 . The pRB and p107 proteins are structurally related and have several characteristics in common, including that they both bind to the SV40 large T oncoprotein as well as to E1A. Cyclin A and p33 cdk2 are thought to function in the control of the cell cycle. They bind to one another, forming a kinase that closely resembles the cell cycle-regulating complexes containing p34 cdc2 . Cyclin A is now shown to bind to p107 in the absence of E1A. The association of p107 with cyclin A suggests a direct link between cell cycle control and the function of p107.
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Cites
DeCaprio, J. A., Ludlow, J. W., Lynch, D., Furukawa, Y., Griffin, J., Piwnica-Worms, H., Huang, C.-M., & Livingston, D. M. (1989) · Cell · doi:10.1016/0092-8674(89)90507-2 · Cited by 897
Self-citation
Cited by
(1993) · Genes & Development · doi:10.1101/gad.7.3.331 · Cited by 1,264
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
Ewen, M. E., Sluss, H. K., Sherr, C. J., Matsushime, H., Kato, J.-Y., & Livingston, D. M. (1993) · Cell · doi:10.1016/0092-8674(93)90136-e · Cited by 1,010
Self-citationMammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
Wang, T. C., Cardiff, R. D., Zukerberg, L., Lees, E., Arnold, A., & Schmidt, E. V. (1994) · Nature · doi:10.1038/369669a0 · Cited by 965
Matsushime, H., Ewen, M. E., Strom, D. K., Kato, J.-Y., Hanks, S. K., Roussel, M. F., & Sherr, C. J. (1992) · Cell · doi:10.1016/0092-8674(92)90360-o · Cited by 897
Self-citationNegative Regulation of G1 in Mammalian Cells: Inhibition of Cyclin E-Dependent Kinase by TGF-β
Koff, A., Ohtsuki, M., Polyak, K., Roberts, J. M., & Massagué, J. (1993) · Science · doi:10.1126/science.8475385 · Cited by 567
Metadata
- Authors
- Faha, B., Ewen, M. E., Tsai, L.-H., Livingston, D. M., & Harlow, E.
- Venue
- Science
- Published
- 1992-01-03
- Volume
- 255
- Issue
- 5040
- Pages
- 87-90
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2035189704
- Cited by
- 210
- References
- 1
- FWCI
- 16.08
- Type
- journal article
- Language
- en
- Open access
- closed
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- Faha, B., Ewen, M. E., Tsai, L.-H., Livingston, D. M., & Harlow, E. (1992). Interaction Between Human Cyclin A and Adenovirus E1A-Associated p107 Protein. Science. https://doi.org/10.1126/science.1532458
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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