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Herpes-Type Virus and Chromosome Marker in Normal Leukocytes after Growth with Irradiated Burkitt Cells

Henle, Werner, Diehl, Volker, Kohn, Gertrude, zur Hausen, Harald, Henle, Gertrude·1967·Science

Abstract

Cultured cells derived from male patients with Burkitt's lymphoma and harboring herpes-type virus particles were lethally irradiated. These irradiated cells induced normal peripheral leukocytes of female infants to grow within 2 to 4 weeks after mixed cultivation. Cells of a line free of this agent failed to stimulate growth. If either type of cell was cultured separately, it did not survive under the experimental conditions. Herpes-type viral antigen and C-group chromosomal marker previously described in cultured Burkitt cells were found in all of the female cell cultures that were obtained.

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Metadata

Authors
Henle, W., Diehl, V., Kohn, G., zur Hausen, H., & Henle, G.
Venue
Science
Published
1967-09
Volume
157
Issue
3792
Pages
1064-1065
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2080249344
Cited by
588
References
0
FWCI
28.26
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Herpes-Type Virus and Chromosome Marker in Normal Leukocytes after Growth with Irradiated Burkitt Cells. https://app.cochat.ai/papers/10.1126/science.157.3792.1064
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Henle, W., Diehl, V., Kohn, G., zur Hausen, H., & Henle, G. (1967). Herpes-Type Virus and Chromosome Marker in Normal Leukocytes after Growth with Irradiated Burkitt Cells. Science. https://doi.org/10.1126/science.157.3792.1064

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.