The DOI matches its Crossref record.
Sickle-Cell Trait in Human Biological and Cultural Evolution: Development of agriculture causing increased malaria is bound to gene-pool changes causing malaria reduction.
Abstract
The particular agricultural adaptation we have been considering is the ultimate determinant of the presence of malaria parasites in the intracellular environment of the human red blood cell. This change in the cellular environment is deleterious for normal individuals, but individuals with the sickle-cell gene are capable of changing their red-cell environment so that intense parasitism never develops. Normal individuals suffer higher mortality rates and lower fertility rates in a malarious environment than individuals with the sickle-cell trait do, so the latter contribute proportionately more people to succeeding generations.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Tishkoff, S. A., Varkonyi, R., Cahinhinan, N., Abbes, S., Argyropoulos, G., Destro-Bisol, G., Drousiotou, A., Dangerfield, B., Lefranc, G., Loiselet, J., et al. (2001) · Science · doi:10.1126/science.1061573 · Cited by 630
The Anthropology of Infectious Disease
Inhorn, M. C., & Brown, P. J. (1990) · Annual Review of Anthropology · doi:10.1146/annurev.an.19.100190.000513 · Cited by 264
From Stagnation to Growth: Unified Growth Theory
Galor, O. (2005) · SSRN Electronic Journal · doi:10.2139/ssrn.651526 · Cited by 257
Adams, J., & Ward, R. H. (1973) · Science · doi:10.1126/science.180.4091.1137 · Cited by 121
Laval, G., Peyrégne, S., Zidane, N., Harmant, C., Renaud, F., Patin, E., Prugnolle, F., & Quintana-Murci, L. (2019) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2019.02.007 · Cited by 55
Metadata
- Authors
- Wiesenfeld, S. L.
- Venue
- Science
- Published
- 1967-09-08
- Volume
- 157
- Issue
- 3793
- Pages
- 1134-1140
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2073718116
- Cited by
- 159
- References
- 0
- FWCI
- 6.02
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Sickle-Cell Trait in Human Biological and Cultural Evolution: Development of agriculture causing increased malaria is bound to gene-pool changes causing malaria reduction. https://app.cochat.ai/papers/10.1126/science.157.3793.1134
- The paper
- Wiesenfeld, S. L. (1967). Sickle-Cell Trait in Human Biological and Cultural Evolution: Development of agriculture causing increased malaria is bound to gene-pool changes causing malaria reduction. Science. https://doi.org/10.1126/science.157.3793.1134
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
