The DOI matches its Crossref record.
Calcium Transient in Presynaptic Terminal of Squid Giant Synapse: Detection with Aequorin
Abstract
Microinjection of aequorin, a bioluminescent protein sensitive to calcium, into the presynaptic terminal of the squid giant synapse demonstrated an increase in intracellular calcium ion concentration during repetitive synaptic transmission. Although no light flashes synchronous with individual presynaptic action potentials were detected, the results are considered consistent with the hypothesis that entry of calcium into the presynaptic terminal triggers release of the synaptic transmitter substance.
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Citations
Cited by
Changeux, J.-P., & Danchin, A. (1976) · Nature · doi:10.1038/264705a0 · Cited by 1,448
Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts
Stewart, M. P., Langer, R., & Jensen, K. F. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00678 · Cited by 747
Blaustein, M. P. (1975) · The Journal of Physiology · doi:10.1113/jphysiol.1975.sp010950 · Cited by 553
Knight, D. E., & Baker, P. F. (1982) · The Journal of Membrane Biology · doi:10.1007/bf01872259 · Cited by 489
Relation between mitochondrial calcium transport and control of energy metabolism
Hansford, R. G. (1985) · Reviews of Physiology, Biochemistry and Pharmacology · doi:10.1007/bfb0034084 · Cited by 370
Metadata
- Authors
- Llinás, R., Blinks, J. R., & Nicholson, C.
- Venue
- Science
- Published
- 1972-06-09
- Volume
- 176
- Issue
- 4039
- Pages
- 1127-1129
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1974730578
- Cited by
- 171
- References
- 0
- FWCI
- 5.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Calcium Transient in Presynaptic Terminal of Squid Giant Synapse: Detection with Aequorin. https://app.cochat.ai/papers/10.1126/science.176.4039.1127
- The paper
- Llinás, R., Blinks, J. R., & Nicholson, C. (1972). Calcium Transient in Presynaptic Terminal of Squid Giant Synapse: Detection with Aequorin. Science. https://doi.org/10.1126/science.176.4039.1127
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
